(Q61660819)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21344648%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

New huprine derivatives functionalized at position 9 as highly potent acetylcholinesterase inhibitors (English)

1 reference

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23 January 2020

1

1 reference

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23 January 2020

Ludovic Jean

6

1 reference

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23 January 2020

Pierre-Yves Renard

7

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23 January 2020

author name string

Richard Foucault

2

1 reference

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23 January 2020

Emilie Gillon

3

1 reference

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23 January 2020

Pierre Bohn

4

1 reference

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23 January 2020

Florian Nachon

5

1 reference

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23 January 2020

publication date

23 February 2011

1 reference

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23 January 2020

number of pages

13

1 reference

inferred from page(s)

published in

ChemMedChem

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23 January 2020

volume

6

1 reference

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23 January 2020

page(s)

876-888

1 reference

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23 January 2020

issue

5

1 reference

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Deciphering the molecular basis of memory failure in Alzheimer's disease

23 January 2020

cites work

1 reference

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7 January 2021

The cholinergic hypothesis of Alzheimer's disease: a review of progress

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7 January 2021

Editorial [Hot Topic: Alzheimer Drug Design Based on the Amyloid Hypothesis (Executive Editors: D. Munoz-Torrero and P. Camps)]

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7 January 2021

Targeting beta-amyloid pathogenesis through acetylcholinesterase inhibitors

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7 January 2021

Selective loss of central cholinergic neurons in Alzheimer's disease

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7 January 2021

Current Treatment for Alzheimer Disease and Future Prospects

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7 January 2021

Medicinal chemistry approaches for the treatment and prevention of Alzheimer's disease

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7 January 2021

Treatment of Alzheimer's disease

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7 January 2021

Safety of tacrine: clinical trials, treatment IND, and postmarketing experience

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7 January 2021

Synthesis, in Vitro Pharmacology, and Molecular Modeling of Very Potent Tacrine−Huperzine A Hybrids as Acetylcholinesterase Inhibitors of Potential Interest for the Treatment of Alzheimer's Disease

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7 January 2021

New tacrine-huperzine A hybrids (huprines): highly potent tight-binding acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's disease

1 reference

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7 January 2021

Synthesis and evaluation of tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease.

1 reference

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7 January 2021

Binding of 13-Amidohuprines to Acetylcholinesterase: Exploring the Ligand-Induced Conformational Change of the Gly117-Gly118 Peptide Bond in the Oxyanion Hole

1 reference

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7 January 2021

Effects of (+/-)-huprine Y and (+/-)-huprine Z, two new anticholinesterasic drugs, on muscarinic receptors

1 reference

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7 January 2021

Synthesis and structure-activity relationship of Huprine derivatives as human acetylcholinesterase inhibitors

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7 January 2021

Neuroprotective effects of (+/-)-huprine Y on in vitro and in vivo models of excitoxicity damage

1 reference

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7 January 2021

Synthesis and pharmacological evaluation of huprine-tacrine heterodimers: subnanomolar dual binding site acetylcholinesterase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000523

7 January 2021

Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.

1 reference

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7 January 2021

Novel huprine derivatives with inhibitory activity toward β-amyloid aggregation and formation as disease-modifying anti-Alzheimer drug candidates

1 reference

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7 January 2021

Synthesis and antibacterial activity of 5-substituted oxazolidinones

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7 January 2021

3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 A resolution: kinetic and molecular dynamic correlates

1 reference

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7 January 2021

In situ selection of lead compounds by click chemistry: target-guided optimization of acetylcholinesterase inhibitors

1 reference

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7 January 2021

In situ click chemistry: enzyme inhibitors made to their own specifications

1 reference

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7 January 2021

Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks

1 reference

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7 January 2021

NMR Chemical Shifts of Common Laboratory Solvents as Trace Impurities

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000523

7 January 2021

A new and rapid colorimetric determination of acetylcholinesterase activity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000523

7 January 2021

Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000523

7 January 2021

Nonequilibrium analysis alters the mechanistic interpretation of inhibition of acetylcholinesterase by peripheral site ligands

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000523

7 January 2021

PHENIX: building new software for automated crystallographic structure determination

1 reference

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7 January 2021

GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

1 reference

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7 January 2021

Comparison of multiple Amber force fields and development of improved protein backbone parameters

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7 January 2021

UCSF Chimera--a visualization system for exploratory research and analysis

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7 January 2021

Development and testing of a general amber force field

1 reference

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7 January 2021

Identifiers

DOI

10.1002/CMDC.201000523

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21344648%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference