(Q61810414)

English

Differential Expression Patterns of Glycolytic Enzymes and Mitochondria-Dependent Apoptosis in PCOS Patients with Endometrial Hyperplasia, an Early Hallmark of Endometrial Cancer, and the Impact of Metformin

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scholarly article

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Differential Expression Patterns of Glycolytic Enzymes and Mitochondria-Dependent Apoptosis in PCOS Patients with Endometrial Hyperplasia, an Early Hallmark of Endometrial Cancer, and the Impact of Metformin (English)

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endometrial hyperplasia

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endometrial cancer

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Mats Brännström

9

object named as

Mats Brännström

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author name string

Tao Wang

1

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Jiao Zhang

2

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Min Hu

3

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Yuehui Zhang

4

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Peng Cui

5

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Xin Li

6

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Juan Li

7

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Edvin Vestin

8

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Linus R Shao

10

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Håkan Billig

11

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language of work or name

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publication date

2019

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International Journal of Biological Sciences

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15

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3

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714-725

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Enzymes of glucose metabolism in carcinoma of the cervix and endometrium of the human uterus

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dating the endometrial biopsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histological changes in the genital tract in transsexual women following androgen therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogenic regulation of uterine pyruvate kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin reduction with metformin increases luteal phase serum glycodelin and insulin-like growth factor-binding protein 1 concentrations and enhances uterine vascularity and blood flow in the polycystic ovary syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Obesity, endogenous hormones, and endometrial cancer risk: a synthetic review

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polycystic ovary syndrome and endometrial carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS).

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of atypical endometrial hyperplasia with an insulin-sensitizing agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in human endometrium and endometriosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of glycolysis-role of insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uterine effects of metformin administration in anovulatory women with polycystic ovary syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of metformin and rosiglitazone, alone and in combination, on the ovary and endometrium in polycystic ovary syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced Expression of Nuclear-Encoded Genes Involved in Mitochondrial Oxidative Metabolism in Skeletal Muscle of Insulin-Resistant Women With Polycystic Ovary Syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metformin for the treatment of the polycystic ovary syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reverse of progestin-resistant atypical endometrial hyperplasia by metformin and oral contraceptives

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence-based and potential benefits of metformin in the polycystic ovary syndrome: a comprehensive review

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional profiling with a pathway-oriented analysis identifies dysregulated molecular phenotypes in the endometrium of patients with polycystic ovary syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hormone receptor dynamics in a receptive human endometrium.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polycystic ovary syndrome and the risk of gynaecological cancer: a systematic review

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metformin reverses hexokinase and 6-phosphofructo-1-kinase inhibition in skeletal muscle, liver and adipose tissues from streptozotocin-induced diabetic mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polycystic ovary syndrome increases the risk of endometrial cancer in women aged less than 50 years: an Australian case-control study

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polycystic ovary syndrome: etiology, pathogenesis and diagnosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prospective evaluation of insulin resistance among endometrial cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose transporters in the uterus: an analysis of tissue distribution and proposed physiological roles

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of Oxidative Stress and Human Leukocyte/Endothelial Cell Interactions in Polycystic Ovary Syndrome Patients with Insulin Resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of TFAM-associated proteins in mitochondrial RNA metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aerobic glycolysis: meeting the metabolic requirements of cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coordinate regulation of heterogeneous nuclear ribonucleoprotein dynamics by steroid hormones in the human fallopian tube and endometrium in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metformin reverses hexokinase and phosphofructokinase downregulation and intracellular distribution in the heart of diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological roles of mitochondrial reactive oxygen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fertility-preserving treatment and pregnancy outcomes in the early stage of endometrial carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sites of reactive oxygen species generation by mitochondria oxidizing different substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Looking at nuclear receptors from a new angle

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metformin use and endometrial cancer survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metformin is associated with improved survival in endometrial cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of pyruvate metabolism and human disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progesterone receptor isoforms A and B: new insights into the mechanism of progesterone resistance for the treatment of endometrial carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endometrial progesterone resistance and PCOS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estradiol-17β upregulates pyruvate kinase M2 expression to coactivate estrogen receptor-α and to integrate metabolic reprogramming with the mitogenic response in endometrial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PCOS and obesity: insulin resistance might be a common etiology for the development of type I endometrial carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination of Diane-35 and Metformin to Treat Early Endometrial Carcinoma in PCOS Women with Insulin Resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct effects of metformin in the endometrium: a hypothetical mechanism for the treatment of women with PCOS and endometrial carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metformin in reproductive health, pregnancy and gynaecological cancer: established and emerging indications

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversing the reduced level of endometrial GLUT4 expression in polycystic ovary syndrome: a mechanistic study of metformin action.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism alteration in follicular niche: The nexus among intermediary metabolism, mitochondrial function, and classic polycystic ovary syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic options for management of endometrial hyperplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Promising clinical practices of metformin in women with PCOS and early-stage endometrial cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of cyclical fluctuations of endometrial GLUT4 expression in women with polycystic ovary syndrome: Evidence for direct regulation of GLUT4 by steroid hormones

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of Androgen Receptor Expression Alters AMPK Phosphorylation in the Endometrium: In Vivo and In Vitro Studies in Women with Polycystic Ovary Syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polycystic ovary syndrome: Endometrial markers

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Criteria, prevalence, and phenotypes of polycystic ovary syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular characterization of insulin resistance and glycolytic metabolism in the rat uterus

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polycystic ovary syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PKM2, cancer metabolism, and the road ahead

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New concepts for an old problem: the diagnosis of endometrial hyperplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective progesterone receptor modulator (SPRM) ulipristal acetate (UPA) and its effects on the human endometrium.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metformin Ameliorates Uterine Defects in a Rat Model of Polycystic Ovary Syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic syndrome enhances endoplasmic reticulum, oxidative stress and leukocyte-endothelium interactions in PCOS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin action and resistance in obesity and type 2 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic Pathways of the Warburg Effect in Health and Disease: Perspectives of Choice, Chain or Chance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress in granulosa cells contributes to poor oocyte quality and IVF-ET outcomes in women with polycystic ovary syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uterine progesterone signaling is a target for metformin therapy in PCOS-like rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local Cortisol Elevation Contributes to Endometrial Insulin Resistance in Polycystic Ovary Syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endometrial progesterone receptor isoforms in women with polycystic ovary syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beyond fertility: polycystic ovary syndrome and long-term health

1 reference

https://pubmed.ncbi.nlm.nih.gov/30745857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary extraosseous Ewing sarcoma of the lung in children

1 reference

12 January 2024

https://opencitations.net/index/api/v1/citations/10.3332/ECANCER.2013.312

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10.7150/IJBS.31425

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