(Q62272734)

English

Evaluation of Nigrostriatal Neurodegeneration and Neuroinflammation Following Repeated Intranasal 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) Administration in Mice, an Experimental Model of Parkinson’s Disease

scientific article published on 21 May 2013

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scholarly article

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23690159%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Evaluation of nigrostriatal neurodegeneration and neuroinflammation following repeated intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in mice, an experimental model of Parkinson's disease (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23690159%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

0 references

neurodegeneration

1 reference

based on heuristic

inferred from title

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23690159%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23690159%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Rui Daniel Prediger

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23690159%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

author name string

Majid Amar

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23690159%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Ines Latrous

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23690159%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Fabrine S M Tristão

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23690159%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Rita Raisman-Vozari

7

1 reference

Europe PubMed Central

PubMed publication ID

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1 March 2020

publication date

21 May 2013

1 reference

Europe PubMed Central

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1 March 2020

Neurotoxicity Research

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23690159%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

25

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23690159%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23690159%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

24-32

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23690159%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

https://scigraph.springernature.com/pub.10.1007/s12640-013-9401-8

0 references

In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intranasal administration of neurotoxicants in animals: support for the olfactory vector hypothesis of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiology of neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: implications for Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice with genetic deletion of the heparin-binding growth factor midkine exhibit early preclinical features of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rate of cell death in parkinsonism indicates active neuropathological process

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of nuclear transcription factor kappa B (NF-kappaB) for MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahyropyridine)-induced apoptosis in nigral neurons of mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lithium and valproate prevent olfactory discrimination and short-term memory impairments in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) rat model of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The olfactory vector hypothesis of neurodegenerative disease: is it viable?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate uptake

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of hepatic microsomal metabolism as an in vivo detoxication pathway of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intranasal delivery of erythropoietin plus insulin-like growth factor-I for acute neuroprotection in stroke. Laboratory investigation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

VMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diagnosis and treatment of Parkinson disease: molecules to medicine

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium transients in astrocyte endfeet cause cerebrovascular constrictions

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Theaflavin ameliorates behavioral deficits, biochemical indices and monoamine transporters expression against subacute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mouse model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model: a tool to explore the pathogenesis of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of neuroinflammation on the pathogenesis of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animal models of Parkinson's disease: limits and relevance to neuroprotection studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The MPTP model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The impact of age and gender on the striatal astrocytes activation in murine model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The risk is in the air: Intranasal administration of MPTP to rats reproducing clinical features of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proanthocyanidin-rich fraction from Croton celtidifolius Baill confers neuroprotection in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine rat model of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurochemical and behavioral effects of systematic and intranigral administration of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences between subacute and chronic MPTP mice models: investigation of dopaminergic neuronal degeneration and alpha-synuclein inclusions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in cytokines and neurotrophins in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of NMDA receptors in both MPTP-induced neuroinflammation and deficits in episodic-like memory in Wistar rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional differences in astrocyte activation in HIV-associated dementia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Permanent human parkinsonism due to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): seven cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Doxycycline restrains glia and confers neuroprotection in a 6-OHDA Parkinson model

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent penetration of MPTP through the nasal route induces Parkinson's disease in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aspirin and salicylate protect against MPTP-induced dopamine depletion in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxin-based models of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxin-induced models of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue concentrations of MPTP and MPP+ after administration of lethal and sublethal doses of MPTP to mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 mice models early preclinical phase of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MPTP lesion causes neuroinflammation and deficits in object recognition in Wistar rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of intranasal infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) upon catecholamine concentrations within olfactory bulbs and corpus striatum of male mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The activities of butyrylcholinesterase and carbonic anhydrase, the rate of anaerobic glycolysis, and the question of a constant density of glial cells in cerebral cortices of various mammalian species from mouse to whale

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathology of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modeling PD pathogenesis in mice: advantages of a chronic MPTP protocol

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkin-knockout mice did not display increased vulnerability to intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity with blood-brain barrier monoamine oxidase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain metabolism dictates the polarity of astrocyte control over arterioles

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MPTP susceptibility in the mouse: behavioral, neurochemical, and histological analysis of gender and strain differences.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkinson's disease: mechanisms and models

1 reference

https://pubmed.ncbi.nlm.nih.gov/23690159

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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