(Q62513281)

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5-Aminoimidazole-4-carboxamide ribonucleotide-transformylase and inosine-triphosphate-pyrophosphatase genes variants predict remission rate during methotrexate therapy in patients with juvenile idiopathic arthritis

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240429%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

5-Aminoimidazole-4-carboxamide ribonucleotide-transformylase and inosine-triphosphate-pyrophosphatase genes variants predict remission rate during methotrexate therapy in patients with juvenile idiopathic arthritis (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240429%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

juvenile rheumatoid arthritis

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240429%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Gabriele Stocco

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240429%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Valentina Moressa

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240429%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Giuliana Decorti

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240429%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Alessandro Ventura

9

1 reference

Europe PubMed Central

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16 February 2020

author name string

Luigi Zandonà

4

1 reference

Europe PubMed Central

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16 February 2020

Diego Favretto

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240429%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Noelia Malusà

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240429%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Loredana Lepore

8

1 reference

Europe PubMed Central

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16 February 2020

publication date

21 September 2014

1 reference

Europe PubMed Central

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16 February 2020

Rheumatology International

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25240429%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

35

1 reference

Europe PubMed Central

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16 February 2020

619-627

1 reference

Europe PubMed Central

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16 February 2020

4

1 reference

Europe PubMed Central

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16 February 2020

https://scigraph.springernature.com/pub.10.1007/s00296-014-3131-y

0 references

PACSIN2 polymorphism influences TPMT activity and mercaptopurine-related gastrointestinal toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A randomized trial of parenteral methotrexate comparing an intermediate dose with a higher dose in children with juvenile idiopathic arthritis who failed to respond to standard doses of methotrexate

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetic and metabolite measurements are associated with clinical status in patients with rheumatoid arthritis treated with methotrexate: results of a multicentred cross sectional observational study

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Juvenile idiopathic arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Current developments in the use of biomarkers for juvenile idiopathic arthritis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preliminary definition of improvement in juvenile arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development and validation of a composite disease activity score for juvenile idiopathic arthritis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of erythrocyte inosine triphosphate pyrophosphohydrolase (ITPA) activity by HPLC and correlation of ITPA genotype-phenotype in a Caucasian population

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic polymorphisms in key methotrexate pathway genes are associated with response to treatment in rheumatoid arthritis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigation of candidate polymorphisms and disease activity in rheumatoid arthritis patients on methotrexate

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomized, placebo-controlled, crossover trial of low-dose oral methotrexate in children with extended oligoarticular or systemic arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase, adenosine deaminase and 5'-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PharmGKB summary: methotrexate pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimization of pediatric rheumatology therapeutics

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preliminary criteria for clinical remission for select categories of juvenile idiopathic arthritis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced folate carrier-1 80G>A polymorphism affects methotrexate treatment outcome in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene-gene interactions in folate and adenosine biosynthesis pathways affect methotrexate efficacy and tolerability in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of novel pharmacogenomic candidates in response to methotrexate in juvenile idiopathic arthritis: correlation between gene expression and genotype.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and safety of oral and parenteral methotrexate therapy in children with juvenile idiopathic arthritis: an observational study with patients from the German Methotrexate Registry

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The estimation and significance of the logarithm of a ratio of frequencies

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of common polymorphisms in reduced folate carrier and gamma-glutamylhydrolase to methotrexate polyglutamate levels in patients with rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate polyglutamates in erythrocytes are associated with lower disease activity in juvenile idiopathic arthritis patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of polymorphisms within the methotrexate pathway genes on the toxicity and efficacy of methotrexate in patients with juvenile idiopathic arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABCB1 and ABCC3 gene polymorphisms are associated with first-year response to methotrexate in juvenile idiopathic arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patterns of interaction between genetic and nongenetic attributes and methotrexate efficacy in rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate in resistant juvenile rheumatoid arthritis. Results of the U.S.A.-U.S.S.R. double-blind, placebo-controlled trial. The Pediatric Rheumatology Collaborative Study Group and The Cooperative Children's Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trial of early aggressive therapy in polyarticular juvenile idiopathic arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25240429

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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