(Q62572413)

English

Structural elements of primary CCR5-using HIV-1 gp120 proteins influencing sensitivity and resistance to the broadly neutralizing monoclonal antibody b12

article

In more languages

default values for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22818780%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Structural elements of primary CCR5-using HIV-1 gp120 proteins influencing sensitivity and resistance to the broadly neutralizing monoclonal antibody b12 (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22818780%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Jasminka Sterjovski

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22818780%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Paul A. Ramsland

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22818780%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Steven L Wesselingh

4

object named as

Steve L Wesselingh

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22818780%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

author name string

Anne Ellett

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22818780%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Melissa J Churchill

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22818780%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Paul R Gorry

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22818780%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

language of work or name

0 references

publication date

19 July 2012

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22818780%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

number of pages

11

1 reference

based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22818780%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

432

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22818780%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22818780%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

394-404

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22818780%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Computational prediction of the cross-reactive neutralizing epitope corresponding to the [corrected] monclonal [corrected] antibody b12 specific for HIV-1 gp120.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Alternative coreceptor requirements for efficient CCR5- and CXCR4-mediated HIV-1 entry into macrophages

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Core structure of gp41 from the HIV envelope glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Single-molecule analysis of human immunodeficiency virus type 1 gp120-receptor interactions in living cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Identification of a major co-receptor for primary isolates of HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Characterization of human immunodeficiency virus type 1 monomeric and trimeric gp120 glycoproteins stabilized in the CD4-bound state: antigenicity, biophysics, and immunogenicity

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Natural resistance of human immunodeficiency virus type 1 to the CD4bs antibody b12 conferred by a glycan and an arginine residue close to the CD4 binding loop

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Determinants flanking the CD4 binding loop modulate macrophage tropism of human immunodeficiency virus type 1 R5 envelopes

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Loss of the N-linked glycosylation site at position 386 in the HIV envelope V4 region enhances macrophage tropism and is associated with dementia.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Envelope glycoprotein determinants of increased fusogenicity in a pathogenic simian-human immunodeficiency virus (SHIV-KB9) passaged in vivo

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Genetic and functional analysis of R5X4 human immunodeficiency virus type 1 envelope glycoproteins derived from two individuals homozygous for the CCR5delta32 allele

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Tissue-specific sequence alterations in the human immunodeficiency virus type 1 envelope favoring CCR5 usage contribute to persistence of dual-tropic virus in the brain

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Inference of macromolecular assemblies from crystalline state

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Mechanism of neutralization by the broadly neutralizing HIV-1 monoclonal antibody VRC01.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Molecular architecture of native HIV-1 gp120 trimers

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

V2 loop glycosylation of the human immunodeficiency virus type 1 SF162 envelope facilitates interaction of this protein with CD4 and CCR5 receptors and protects the virus from neutralization by anti-V3 loop and anti-CD4 binding site antibodies

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

N-linked glycosylation of the V3 loop and the immunologically silent face of gp120 protects human immunodeficiency virus type 1 SF162 from neutralization by anti-gp120 and anti-gp41 antibodies

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

A human IgG1 (b12) specific for the CD4 binding site of HIV-1 neutralizes by inhibiting the virus fusion entry process, but b12 Fab neutralizes by inhibiting a postfusion event

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Intrapatient alterations in the human immunodeficiency virus type 1 gp120 V1V2 and V3 regions differentially modulate coreceptor usage, virus inhibition by CC/CXC chemokines, soluble CD4, and the b12 and 2G12 monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Rapid evolution of the neutralizing antibody response to HIV type 1 infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

HIV-1 predisposed to acquiring resistance to maraviroc (MVC) and other CCR5 antagonists in vitro has an inherent, low-level ability to utilize MVC-bound CCR5 for entry

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

HIV-1 escape from the CCR5 antagonist maraviroc associated with an altered and less-efficient mechanism of gp120-CCR5 engagement that attenuates macrophage tropism

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Comparative protein modelling by satisfaction of spatial restraints

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

HIV gp120: double lock strategy foils host defences

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Human immunodeficiency virus type 1 neutralization is determined by epitope exposure on the gp120 oligomer

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Mobility of the human immunodeficiency virus (HIV) receptor CD4 and coreceptor CCR5 in living cells: implications for HIV fusion and entry events

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

CD4-binding site alterations in CCR5-using HIV-1 envelopes influencing gp120-CD4 interactions and fusogenicity

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

An altered and more efficient mechanism of CCR5 engagement contributes to macrophage tropism of CCR5-using HIV-1 envelopes

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Antibody neutralization and escape by HIV-1

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Mechanism of human immunodeficiency virus type 1 resistance to monoclonal antibody B12 that effectively targets the site of CD4 attachment

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

The antigenic structure of the HIV gp120 envelope glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Stoichiometry of antibody neutralization of human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Characterization of the outer domain of the gp120 glycoprotein from human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Improved elicitation of neutralizing antibodies against primary human immunodeficiency viruses by soluble stabilized envelope glycoprotein trimers

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Structural definition of a conserved neutralization epitope on HIV-1 gp120

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Molecular features of the broadly neutralizing immunoglobulin G1 b12 required for recognition of human immunodeficiency virus type 1 gp120.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Neutralization of human immunodeficiency virus type 1 by antibody to gp120 is determined primarily by occupancy of sites on the virion irrespective of epitope specificity

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

Diminished production of human immunodeficiency virus type 1 in astrocytes results from inefficient translation of gag, env, and nef mRNAs despite efficient expression of Tat and Rev

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

based on heuristic

inferred from DOI database lookup

Cross-neutralizing activity against divergent human immunodeficiency virus type 1 isolates induced by the gp41 sequence ELDKWAS.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

based on heuristic

inferred from DOI database lookup

Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

based on heuristic

inferred from DOI database lookup

Cross-clade neutralization of primary isolates of human immunodeficiency virus type 1 by human monoclonal antibodies and tetrameric CD4-IgG.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

based on heuristic

inferred from DOI database lookup

Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.024

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/J.VIROL.2012.06.024

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22818780%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22818780%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q62572413&oldid=1772541244"