(Q62666886)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

title

ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

Roundabout guidance receptor 4

4 May 2020

main subject

1 reference

establishment of endothelial barrier

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

bicuspid aortic valve

1 reference

inferred from title

thoracic aortic aneurysm

1 reference

inferred from title

author

Manuel A Seman-Senderos

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Florian Wünnemann

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Ilse Luyckx

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Aline Verstraeten

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Vinod Jaskula-Ranga

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Henrik Lauridsen

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Patrick T Ellinor

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Honghuang Lin

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Christian Lino Cardenas

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Jonathan T Butcher

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Judith Verhagen

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Seema Mital

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Gregor Andelfinger

43

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Andrew S McCallion

44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Harry C Dietz

45

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

31

Mark E Lindsay

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

41

Lut Van Laer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

42

Bart L Loeys

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

author name string

Russell A Gould

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Hamza Aziz

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Courtney E Woods

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Elizabeth Sparks

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Christoph Preuss

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Djahida Bedja

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Cassandra R Moats

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Sarah A McClymont

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Rebecca Rose

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Nara Sobreira

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Hua Ling

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Gretchen MacCarrick

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Ajay Anand Kumar

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Elyssa Cannaerts

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Hanna M Björk

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Ann-Cathrin Lehsau

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Asad A Shah

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Christopher L Bennett

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Eric M Isselbacher

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

G Chad Hughes

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Luc Mertens

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Anders Franco-Cereceda

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Marja Wessels

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Salah A Mohamed

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Baylor-Hopkins Center for Mendelian Genomics

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

MIBAVA Leducq Consortium

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

Per Eriksson

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

language of work or name

English

0 references

publication date

19 November 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

volume

51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

page(s)

42-50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

4 May 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6309588/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/s41588-018-0265-y

0 references

cites work

Clinical and pathophysiological implications of a bicuspid aortic valve.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Aortic and pulmonary stenosis

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Clinical significance of the bicuspid aortic valve

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Ascending aortic dilatation associated with bicuspid aortic valve: pathophysiology, molecular biology, and clinical implications

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Bicuspid aortic valve is heritable

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Mutations in NOTCH1 cause aortic valve disease

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Novel NOTCH1 mutations in patients with bicuspid aortic valve disease and thoracic aortic aneurysms

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Nonsynonymous variants in the SMAD6 gene predispose to congenital cardiovascular malformation

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Familial congenital bicuspid aortic valve: a disorder of uncertain inheritance

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

A prospective study to assess the frequency of familial clustering of congenital bicuspid aortic valve

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Association of aortic valvular disease and cystic medial necrosis of the ascending aorta; report of four instances

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Familial thoracic aortic dilation and bicommissural aortic valve: A prospective analysis of natural history and inheritance

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Thoracic and abdominal aortic aneurysms

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

The Loeys-Dietz syndrome: an update for the clinician

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Mutations in smooth muscle alpha-actin (ACTA2) lead to thoracic aortic aneurysms and dissections.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Targetting of the gene encoding fibrillin-1 recapitulates the vascular aspect of Marfan syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Mutations in myosin light chain kinase cause familial aortic dissections

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Phenotypic spectrum of the SMAD3-related aneurysms–osteoarthritis syndrome

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Aneurysm syndromes caused by mutations in the TGF-beta receptor

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Robo4 is a vascular-specific receptor that inhibits endothelial migration

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Roundabout 4 regulates blood-tumor barrier permeability through the modulation of ZO-1, Occludin, and Claudin-5 expression

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

roundabout4 is essential for angiogenesis in vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Fibrinolytic activity is associated with presence of cystic medial degeneration in aneurysms of the ascending aorta.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Mesenchymal state of intimal cells may explain higher propensity to ascending aortic aneurysm in bicuspid aortic valves

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Notch-dependent EMT is attenuated in patients with aortic aneurysm and bicuspid aortic valve

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Angiotensin II blockade and aortic-root dilation in Marfan's syndrome

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Fast and accurate short read alignment with Burrows-Wheeler transform

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

The Sequence Alignment/Map format and SAMtools

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

A framework for variation discovery and genotyping using next-generation DNA sequencing data

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Integrative genomics viewer

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Multi-scale biomechanical remodeling in aging and genetic mutant murine mitral valve leaflets: insights into Marfan syndrome

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Transforming growth factor β, bone morphogenetic protein, and vascular endothelial growth factor mediate phenotype maturation and tissue remodeling by embryonic valve progenitor cells: relevance for heart valve tissue engineering

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Cyclic strain anisotropy regulates valvular interstitial cell phenotype and tissue remodeling in three-dimensional culture.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Zinc Finger Targeter (ZiFiT): an engineered zinc finger/target site design tool.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

ZiFiT (Zinc Finger Targeter): an updated zinc finger engineering tool

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Genome engineering using the CRISPR-Cas9 system

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0265-Y

7 January 2021

Early surgical experience with Loeys-Dietz: a new syndrome of aggressive thoracic aortic aneurysm disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30455415

12 December 2020

inferred from PubMed ID database lookup

Sch 36605, structure of a novel nucleoside

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.41.123

Identifiers

DOI

10.1038/S41588-018-0265-Y

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30455415%20AND%20SRC:MED&resulttype=core&format=json

4 May 2020

PubMed publication ID

30455415

1 reference