(Q62836306)

English

The Impact of UGT1A8, UGT1A9, and UGT2B7 Genetic Polymorphisms on the Pharmacokinetic Profile of Mycophenolic Acid After a Single Oral Dose in Healthy Volunteers

scientific article published on 01 March 2007

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scholarly article

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17339869%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

The impact of UGT1A8, UGT1A9, and UGT2B7 genetic polymorphisms on the pharmacokinetic profile of mycophenolic acid after a single oral dose in healthy volunteers (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17339869%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

pharmacokinetics

1 reference

based on heuristic

inferred from title

Chantal Guillemette

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17339869%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

author name string

Lévesque E

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17339869%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Delage R

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17339869%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Benoit-Biancamano MO

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17339869%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Caron P

4

1 reference

Europe PubMed Central

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26 December 2019

Bernard O

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17339869%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Couture F

6

1 reference

Europe PubMed Central

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26 December 2019

language of work or name

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publication date

1 March 2007

1 reference

Europe PubMed Central

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26 December 2019

Clinical Pharmacology & Therapeutics

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17339869%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

81

1 reference

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26 December 2019

3

1 reference

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26 December 2019

392-400

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17339869%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Mycophenolates in transplantation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Mycophenolate mofetil and its mechanisms of action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Intraindividual and interindividual variations in the pharmacokinetics of mycophenolic acid in liver transplant patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacokinetics of mycophenolate mofetil are influenced by concomitant immunosuppression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacokinetics help optimizing mycophenolate mofetil dosing in kidney transplant patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Relationship of mycophenolic acid exposure to clinical outcome after hematopoietic cell transplantation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Mycophenolate mofetil for solid organ transplantation: does the evidence support the need for clinical pharmacokinetic monitoring?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

The kinetics of mycophenolic acid and its glucuronide metabolite in adult kidney transplant recipients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

The rationale for and limitations of therapeutic drug monitoring for mycophenolate mofetil in transplantation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Mycophenolic acid 12-h trough level monitoring in renal transplantation: association with acute rejection and toxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of glucoside and carboxyl-linked glucuronide conjugates of mycophenolic acid in plasma of transplant recipients treated with mycophenolate mofetil

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacokinetics and protein adduct formation of the pharmacologically active acyl glucuronide metabolite of mycophenolic acid in pediatric renal transplant recipients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

The main role of UGT1A9 in the hepatic metabolism of mycophenolic acid and the effects of naturally occurring variants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and functional characterization of UDP-glucuronosyltransferases UGT1A8*1, UGT1A8*2 and UGT1A8*3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional Characterization of Human UDP-Glucuronosyltransferase 1A9 Variant, D256N, Found in Japanese Cancer Patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Three novel single nucleotide polymorphisms in UGT1A9

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel functional polymorphism in the uridine diphosphate-glucuronosyltransferase 2B7 promoter with significant impact on promoter activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

The impact of uridine diphosphate-glucuronosyltransferase 1A9 (UGT1A9) gene promoter region single-nucleotide polymorphisms T-275A and C-2152T on early mycophenolic acid dose-interval exposure in de novo renal allograft recipients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacokinetics and concentration-control investigations of mycophenolic acid in adults after transplantation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunosuppression with mycophenolic acid: one size does not fit all.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

The pharmacokinetic-pharmacodynamic relationship for mycophenolate mofetil in renal transplantation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparison of mycophenolic acid pharmacokinetic parameters in kidney transplant patients within the first 3 months post-transplant.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Mycophenolic acid: measurement and relationship to pharmacologic effects.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

A new acute inflammatory syndrome related to the introduction of mycophenolate mofetil in patients with Wegener's granulomatosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacokinetics and bioavailability of mycophenolate mofetil in healthy subjects after single-dose oral and intravenous administration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

A New Statistical Method for Haplotype Reconstruction from Population Data

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100073

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.CLPT.6100073

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17339869%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17339869%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

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