(Q44429351)

2 December 2017

title

Functional characterization of human UDP-glucuronosyltransferase 1A9 variant, D256N, found in Japanese cancer patients (English)

1 reference

2 December 2017

Functional Characterization of Human UDP-Glucuronosyltransferase 1A9 Variant, D256N, Found in Japanese Cancer Patients (English)

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

30 December 2023

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

30 December 2023

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

30 December 2023

11

Atsushi Ohtsu

1 reference

2 December 2017

9

Kuniaki Shirao

1 reference

2 December 2017

10

Hironobu Minami

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12730278

30 December 2023

author name string

Hideto Jinno

1

1 reference

2 December 2017

Mayumi Saeki

2

1 reference

2 December 2017

Yoshiro Saito

3

1 reference

2 December 2017

Toshiko Tanaka-Kagawa

4

1 reference

2 December 2017

Nobumitsu Hanioka

5

1 reference

2 December 2017

Kimie Sai

6

1 reference

2 December 2017

Nahoko Kaniwa

7

1 reference

2 December 2017

Masanori Ando

8

1 reference

2 December 2017

Teruhiko Yoshida

12

1 reference

2 December 2017

Nagahiro Saijo

13

1 reference

2 December 2017

Shogo Ozawa

14

1 reference

2 December 2017

Jun-ichi Sawada

15

1 reference

2 December 2017

language of work or name

English

0 references

publication date

1 May 2003

1 reference

full work available at URL

2 December 2017

https://syndication.highwire.org/content/doi/10.1124/jpet.103.051250

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Journal of Pharmacology and Experimental Therapeutics

30 December 2023

published in

1 reference

2 December 2017

volume

306

1 reference

2 December 2017

issue

2

1 reference

2 December 2017

page(s)

688-693

1 reference

Genetic polymorphisms of the UDP-glucuronosyltransferase 1A7 gene and irinotecan toxicity in Japanese cancer patients

2 December 2017

cites work

2

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

The UDP-glucuronosyltransferase 1A9 enzyme is a peroxisome proliferator-activated receptor alpha and gamma target gene

30 December 2023

4

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism?

30 December 2023

5

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome

30 December 2023

6

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38) by the human UDP-glucuronosyltransferases encoded at the UGT1 locus

30 December 2023

7

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

UDP glucuronosyltransferase mRNA levels in human liver disease

30 December 2023

8

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9

30 December 2023

9

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Drug Metabolism and Disposition

30 December 2023

11

21

50

1993

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank

30 December 2023

12

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38).

30 December 2023

13

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus

30 December 2023

14

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus: functional consequences of three novel missense mutations in the human UGT1A7 gene

30 December 2023

15

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

High-performance liquid chromatographic assay for glucuronidation activity of 7-ethyl-10-hydroxycamptothecin (SN-38), the active metabolite of irinotecan (CPT-11), in human liver microsomes

30 December 2023

17

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothecin

30 December 2023

18

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity

30 December 2023

19

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes

30 December 2023

20

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38), an active metabolite of irinotecan (CPT-11), by human UGT1A1 variants, G71R, P229Q, and Y486D.

30 December 2023

21

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Drug glucuronidation by human renal UDP-glucuronosyltransferases.

30 December 2023

23

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Genetic susceptibility to adverse drug reactions

30 December 2023

24

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Irinotecan dosing: does the CPT in CPT-11 stand for "Can't Predict Toxicity"?

30 December 2023

25

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Expression and inducibility of the human bilirubin UDP-glucuronosyltransferase UGT1A1 in liver and cultured primary hepatocytes: evidence for both genetic and environmental influences

30 December 2023

26

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxycamptothecin (SN-38), by Human Liver Carboxylesterase

30 December 2023

27

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Irinotecan (CPT-11): recent developments and future directions--colorectal cancer and beyond

30 December 2023

28

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8

30 December 2023

29

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR.

30 December 2023

31

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Human UDP-glucuronosyltransferases: metabolism, expression, and disease

30 December 2023

32

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity

30 December 2023

33

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene

30 December 2023

34

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Involvement of the xenobiotic response element (XRE) in Ah receptor-mediated induction of human UDP-glucuronosyltransferase 1A1.

30 December 2023

35

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk

30 December 2023

36

1 reference

https://api.crossref.org/works/10.1124/JPET.103.051250

30 December 2023

Identifiers

1 reference

2 December 2017

1 reference