(Q63246643)

1

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Annette B Vogel

2

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Søren Buus

3

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Stephanie Erbar

4

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Edmund G Wee

5

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Tomáš Hanke

Molecular Therapy. Methods & Clinical Development

7

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language of work or name

English

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publication date

15 March 2019

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published in

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volume

12

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page(s)

32-46

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cites work

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12 December 2020

Self-replicating Semliki Forest virus RNA as recombinant vaccine

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12 December 2020

Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection

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12 December 2020

Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

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12 December 2020

Membrane tumor necrosis factor (TNF) induced cooperative signaling of TNFR60 and TNFR80 favors induction of cell death rather than virus production in HIV-infected T cells

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12 December 2020

Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

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12 December 2020

Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques

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12 December 2020

Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA

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12 December 2020

Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes

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12 December 2020

HLA and HIV-1: heterozygote advantage and B*35-Cw*04 disadvantage

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12 December 2020

Evolution and transmission of stable CTL escape mutations in HIV infection

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12 December 2020

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

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12 December 2020

The influence of HLA genotype on AIDS

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12 December 2020

Signalling pathways of the TNF superfamily: a double-edged sword

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12 December 2020

Ex vivo identification, isolation and analysis of tumor-cytolytic T cells.

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12 December 2020

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

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12 December 2020

T cell cross-reactivity and conformational changes during TCR engagement

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12 December 2020

Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA

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12 December 2020

Tenofovir-associated acute and chronic kidney disease: a case of multiple drug interactions

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12 December 2020

HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

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12 December 2020

Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

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12 December 2020

Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells.

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12 December 2020

CD8+ T-cell responses to different HIV proteins have discordant associations with viral load

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12 December 2020

A whole-genome association study of major determinants for host control of HIV-1

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12 December 2020

Innate recognition of viruses

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12 December 2020

Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover

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12 December 2020

Design and pre-clinical evaluation of a universal HIV-1 vaccine

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12 December 2020

Increased Antigen Presentation Efficiency by Coupling Antigens to MHC Class I Trafficking Signals

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12 December 2020

Broad and Gag-biased HIV-1 epitope repertoires are associated with lower viral loads

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12 December 2020

Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability

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12 December 2020

Distinct genetic loci control plasma HIV-RNA and cellular HIV-DNA levels in HIV-1 infection: the ANRS Genome Wide Association 01 study

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12 December 2020

Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge

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12 December 2020

The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection

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12 December 2020

Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection

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12 December 2020

Direct injection of protamine-protected mRNA: results of a phase 1/2 vaccination trial in metastatic melanoma patients.

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12 December 2020

Risk of myocardial infarction in patients with HIV infection exposed to specific individual antiretroviral drugs from the 3 major drug classes: the data collection on adverse events of anti-HIV drugs (D:A:D) study

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12 December 2020

Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo

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12 December 2020

Long peptides induce polyfunctional T cells against conserved regions of HIV-1 with superior breadth to single-gene vaccines in macaques.

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12 December 2020

Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

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12 December 2020

High prevalence of and progression to low bone mineral density in HIV-infected patients: a longitudinal cohort study

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12 December 2020

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

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12 December 2020

Protective efficacy of serially up-ranked subdominant CD8+ T cell epitopes against virus challenges

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12 December 2020

Definition of the viral targets of protective HIV-1-specific T cell responses

1 reference

12 December 2020

Superior induction of T cell responses to conserved HIV-1 regions by electroporated alphavirus replicon DNA compared to that with conventional plasmid DNA vaccine

1 reference

12 December 2020

Lessons learned from HIV-1 vaccine trials: new priorities and directions

1 reference

12 December 2020

Antiviral inhibitory capacity of CD8+ T cells predicts the rate of CD4+ T-cell decline in HIV-1 infection

1 reference

12 December 2020

HIV and HLA class I: an evolving relationship

1 reference

12 December 2020

Type I IFN counteracts the induction of antigen-specific immune responses by lipid-based delivery of mRNA vaccines.

1 reference

12 December 2020

High acceptability of HIV pre-exposure prophylaxis but challenges in adherence and use: qualitative insights from a phase I trial of intermittent and daily PrEP in at-risk populations in Kenya

1 reference

12 December 2020

Cytomegalovirus vectors violate CD8+ T cell epitope recognition paradigms

1 reference

12 December 2020

Absence of systemic toxicity changes following intramuscular administration of novel pSG2.HIVconsv DNA, ChAdV63.HIVconsv and MVA.HIVconsv vaccines to BALB/c mice

1 reference

12 December 2020

Immune clearance of highly pathogenic SIV infection

1 reference

12 December 2020

Safety, adherence and acceptability of intermittent tenofovir/emtricitabine as HIV pre-exposure prophylaxis (PrEP) among HIV-uninfected Ugandan volunteers living in HIV-serodiscordant relationships: a randomized, clinical trial

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12 December 2020

Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1.

1 reference

12 December 2020

Staufen1 senses overall transcript secondary structure to regulate translation

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12 December 2020

Conserved immunogens in prime-boost strategies for the next-generation HIV-1 vaccines

1 reference

12 December 2020

Safety and tolerability of conserved region vaccines vectored by plasmid DNA, simian adenovirus and modified vaccinia virus ankara administered to human immunodeficiency virus type 1-uninfected adults in a randomized, single-blind phase I trial.

1 reference

12 December 2020

A cationic nanoemulsion for the delivery of next-generation RNA vaccines.

1 reference

12 December 2020

Optimizing parallel induction of HIV type 1-specific antibody and T-cell responses by multicomponent subunit vaccines

1 reference

12 December 2020

Characterization of T-cell responses to conserved regions of the HIV-1 proteome in BALB/c mice

1 reference

12 December 2020

mRNA-based therapeutics--developing a new class of drugs

1 reference

12 December 2020

Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses

1 reference

12 December 2020

Clinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved Epitopes

1 reference

12 December 2020

Transient IL-10 receptor blockade can enhance CD8(+) T cell responses to a simian adenovirus-vectored HIV-1 conserved region immunogen

1 reference

12 December 2020

Humoral responses to HIVconsv induced by heterologous vaccine modalities in rhesus macaques

1 reference

12 December 2020

Increased Valency of Conserved-mosaic Vaccines Enhances the Breadth and Depth of Epitope Recognition

1 reference

12 December 2020

Novel Conserved-region T-cell Mosaic Vaccine With High Global HIV-1 Coverage Is Recognized by Protective Responses in Untreated Infection

1 reference

12 December 2020

Broadly targeted CD8⁺ T cell responses restricted by major histocompatibility complex E.

1 reference

12 December 2020

Assessment of the Safety and Immunogenicity of 2 Novel Vaccine Platforms for HIV-1 Prevention: A Randomized Trial

1 reference

12 December 2020

HIV-Host Interactions: Implications for Vaccine Design

1 reference

12 December 2020

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

1 reference

12 December 2020

An mRNA Vaccine Encoding Rabies Virus Glycoprotein Induces Protection against Lethal Infection in Mice and Correlates of Protection in Adult and Newborn Pigs

1 reference

12 December 2020

Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose

1 reference

12 December 2020

Broad HIV-1 inhibition in vitro by vaccine-elicited CD8(+) T cells in African adults

1 reference

12 December 2020

Cap analogs modified with 1,2-dithiodiphosphate moiety protect mRNA from decapping and enhance its translational potential

1 reference

12 December 2020

Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

1 reference

12 December 2020

HIV-1 Conserved Mosaics Delivered by Regimens with Integration-Deficient DC-Targeting Lentiviral Vector Induce Robust T Cells

1 reference

12 December 2020

The 'anti-hype' vaccine

1 reference

12 December 2020

Induction of an IFN-Mediated Antiviral Response by a Self-Amplifying RNA Vaccine: Implications for Vaccine Design.

1 reference

12 December 2020

Novel, in-natural-infection subdominant HIV-1 CD8+ T-cell epitopes revealed in human recipients of conserved-region T-cell vaccines

1 reference

12 December 2020

Evaluation of the immunogenicity and impact on the latent HIV-1 reservoir of a conserved region vaccine, MVA.HIVconsv, in antiretroviral therapy-treated subjects

1 reference

12 December 2020

Advances in the delivery of RNA therapeutics: from concept to clinical reality.

1 reference

12 December 2020

Improvement of in vivo expression of genes delivered by self-amplifying RNA using Vaccinia Virus immune evasion proteins

1 reference

12 December 2020

Self-Amplifying RNA Vaccines Give Equivalent Protection against Influenza to mRNA Vaccines but at Much Lower Doses.

1 reference

12 December 2020

CD8+ T cells specific for conserved, cross-reactive Gag epitopes with strong ability to suppress HIV-1 replication.

1 reference

12 December 2020