(Q63865766)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29940786%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

title

Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29940786%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

0 references

0 references

0 references

1 reference

1

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2 April 2020

Idil Orhon

2

1 reference

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2 April 2020

Robert P. Coppes

7

1 reference

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2 April 2020

author name string

Cecilia Rocchi

3

1 reference

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2 April 2020

Xingdong Zhou

4

1 reference

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2 April 2020

Morten Luhr

5

1 reference

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2 April 2020

Kerst-Jan Hijlkema

6

1 reference

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2 April 2020

Nikolai Engedal

8

1 reference

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2 April 2020

Muriel Mari

9

1 reference

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2 April 2020

Fulvio Reggiori

10

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2 April 2020

language of work or name

English

0 references

publication date

20 July 2018

1 reference

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2 April 2020

1 reference

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2 April 2020

volume

14

1 reference

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2 April 2020

issue

8

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2 April 2020

page(s)

1435-1455

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describes a project that uses

2 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6103682/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents

1 reference

12 December 2020

Inhibition of the Lysosomal Pathway of Protein Degradation in Isolated Rat Hepatocytes by Ammonia, Methylamine, Chloroquine and Leupeptin

1 reference

12 December 2020

Multiple autophosphorylation sites of the epidermal growth factor receptor are essential for receptor kinase activity and internalization. Contrasting significance of tyrosine 992 in the native and truncated receptors

1 reference

12 December 2020

Proteolysis in isolated autophagic vacuoles from the rat pancreas. Effects of chloroquine administration.

1 reference

12 December 2020

Perturbation of the morphology of the trans-Golgi network following Brefeldin A treatment: redistribution of a TGN-specific integral membrane protein, TGN38

1 reference

12 December 2020

Immunocytochemical characterization of the endocytic and phagolysosomal compartments in peritoneal macrophages

1 reference

12 December 2020

Isolation and analysis of the human 46-kDa mannose 6-phosphate receptor gene

1 reference

12 December 2020

A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein beta-adaptin.

1 reference

12 December 2020

Identification, sequencing and expression of an integral membrane protein of the trans-Golgi network (TGN38)

1 reference

12 December 2020

Nonselective autophagy of cytosolic enzymes by isolated rat hepatocytes

1 reference

12 December 2020

Identification of two lysosomal membrane glycoproteins

1 reference

12 December 2020

Quantitative aspects of cellular autophagocytosis. Morphometric and cell fractionation studies.

1 reference

12 December 2020

Regression of autophagic vacuoles in mouse pancreatic cells: a morphometric study of the effect of methylamine and chloroquine followed by cycloheximide treatment

1 reference

12 December 2020

46 kd mannose 6-phosphate receptor: cloning, expression, and homology to the 215 kd mannose 6-phosphate receptor

1 reference

12 December 2020

Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells

1 reference

12 December 2020

Chloroquine and ammonium chloride prevent terminal glycosylation of immunoglobulins in plasma cells without affecting secretion

1 reference

12 December 2020

Glycoproteins of the lysosomal membrane

1 reference

12 December 2020

Rapid isolation of rat liver secondary lysosomes--autophagic vacuoles--following chloroquine administration

1 reference

12 December 2020

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

12 December 2020

Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages

1 reference

12 December 2020

Redistribution of mannose-6-phosphate receptors induced by tunicamycin and chloroquine

1 reference

12 December 2020

Degradation of microinjected proteins: effects of lysosomotropic agents and inhibitors of autophagy

1 reference

12 December 2020

Inhibition of hepatocytic protein degradation by inducers of autophagosome accumulation.

1 reference

12 December 2020

Morphometric studies of chloroquine-induced changes in hepatocytic organelles in the rat.

1 reference

12 December 2020

EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif

1 reference

12 December 2020

Characterization of a cis-Golgi matrix protein, GM130

1 reference

12 December 2020

4-Aminoquinolines--past, present, and future: a chemical perspective

1 reference

12 December 2020

Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells

1 reference

12 December 2020

Endocytosis of functional epidermal growth factor receptor-green fluorescent protein chimera

1 reference

12 December 2020

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

1 reference

12 December 2020

Abnormal glycosylation and altered Golgi structure in colorectal cancer: dependence on intra-Golgi pH.

1 reference

12 December 2020

Development by self-digestion: molecular mechanisms and biological functions of autophagy

1 reference

12 December 2020

Weak base permeability characteristics influence the intracellular sequestration site in the multidrug-resistant human leukemic cell line HL-60.

1 reference

12 December 2020

Autophagy in health and disease: a double-edged sword

1 reference

12 December 2020

Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes

1 reference

12 December 2020

Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

1 reference

12 December 2020

Cryosectioning and immunolabeling

1 reference

12 December 2020

To be or not to be? Examples of incorrect identification of autophagic compartments in conventional transmission electron microscopy of mammalian cells

1 reference

12 December 2020

The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes

1 reference

12 December 2020

Organization of the pre-autophagosomal structure responsible for autophagosome formation

1 reference

12 December 2020

Autophagy fights disease through cellular self-digestion

1 reference

12 December 2020

Mouse Hepatitis Coronavirus RNA Replication Depends on GBF1-Mediated ARF1 Activation

1 reference

12 December 2020

An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

1 reference

12 December 2020

Elevated Golgi pH impairs terminal N-glycosylation by inducing mislocalization of Golgi glycosyltransferases

1 reference

12 December 2020

Early endosomes and endosomal coatomer are required for autophagy

1 reference

12 December 2020

Regulation mechanisms and signaling pathways of autophagy

1 reference

12 December 2020

Mammalian autophagy: core molecular machinery and signaling regulation

1 reference

12 December 2020

Methods in mammalian autophagy research

1 reference

12 December 2020

Induction of lysosomal dilatation, arrested autophagy, and cell death by chloroquine in cultured ARPE-19 cells

1 reference

12 December 2020

A high content screening assay for identifying lysosomotropic compounds

1 reference

12 December 2020

Autophagy in immunity and inflammation

1 reference

12 December 2020

Double membranes vs. lipid bilayers, and their significance for correct identification of macroautophagic structures

1 reference

12 December 2020

Chloroquine treatment of ARPE-19 cells leads to lysosome dilation and intracellular lipid accumulation: possible implications of lysosomal dysfunction in macular degeneration

1 reference

12 December 2020

Functional organization of Golgi N- and O-glycosylation pathways involves pH-dependent complex formation that is impaired in cancer cells

1 reference

12 December 2020

mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase

1 reference

12 December 2020

The puzzling origin of the autophagosomal membrane

1 reference

12 December 2020

Canonical and non-canonical autophagy: variations on a common theme of self-eating?

1 reference

12 December 2020

Cation trapping by cellular acidic compartments: beyond the concept of lysosomotropic drugs

1 reference

12 December 2020

Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy

1 reference

12 December 2020

Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency

1 reference

12 December 2020

NIH Image to ImageJ: 25 years of image analysis

1 reference

12 December 2020

The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes

1 reference

12 December 2020

Acidic nanoparticles are trafficked to lysosomes and restore an acidic lysosomal pH and degradative function to compromised ARPE-19 cells

1 reference

12 December 2020

Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion.

1 reference

12 December 2020

Use of LysoTracker dyes: a flow cytometric study of autophagy

1 reference

12 December 2020

The anti-malarial chloroquine overcomes primary resistance and restores sensitivity to trastuzumab in HER2-positive breast cancer

1 reference

12 December 2020

Modulation of intracellular calcium homeostasis blocks autophagosome formation

1 reference

12 December 2020

Suppression of lysosome function induces autophagy via a feedback down-regulation of MTOR complex 1 (MTORC1) activity.

1 reference

12 December 2020

Autophagy proteins regulate ERK phosphorylation

1 reference

12 December 2020

Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase

1 reference

12 December 2020

A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy

1 reference

12 December 2020

V-ATPase and osmotic imbalances activate endolysosomal LC3 lipidation

1 reference

12 December 2020

Chloroquine analogues in drug discovery: new directions of uses, mechanisms of actions and toxic manifestations from malaria to multifarious diseases

1 reference

12 December 2020

Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy

1 reference

12 December 2020

Autophagosome-lysosome fusion is independent of V-ATPase-mediated acidification

1 reference

12 December 2020

Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates.

1 reference

12 December 2020

Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy

1 reference

12 December 2020

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

1 reference

12 December 2020

Glycosylation Quality Control by the Golgi Structure

1 reference

12 December 2020

Chloroquine and hydroxychloroquine for cancer therapy

1 reference

12 December 2020

Beta 1-integrin-c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes.

1 reference

12 December 2020

The ATG conjugation systems are important for degradation of the inner autophagosomal membrane.

1 reference

12 December 2020

Autophagosome Maturation and Fusion

1 reference

12 December 2020

A switch from canonical to noncanonical autophagy shapes B cell responses.

1 reference

12 December 2020

A Simple Cargo Sequestration Assay for Quantitative Measurement of Nonselective Autophagy in Cultured Cells.

1 reference

12 December 2020

Pharmacological modulators of autophagy activate a parallel noncanonical pathway driving unconventional LC3 lipidation

1 reference

12 December 2020

Lysosomal adaptation: How cells respond to lysosomotropic compounds

1 reference

12 December 2020

New insights into autophagosome-lysosome fusion

1 reference

12 December 2020

Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

1 reference

12 December 2020

Molecular definitions of autophagy and related processes.

1 reference

12 December 2020

Accumulation of autophagosomes confers cytotoxicity.

1 reference

12 December 2020

Rab7b modulates autophagic flux by interacting with Atg4B.

1 reference

12 December 2020

Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins.

1 reference

12 December 2020

10.1080/15548627.2018.1474314

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29940786%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29940786%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference