(Q63965414)

31 March 2020

12 December 2020

A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes

2 references

31 March 2020

12 December 2020

2 references

31 March 2020

12 December 2020

A superfamily of protein tags: ubiquitin, SUMO and related modifiers

2 references

31 March 2020

12 December 2020

Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation

2 references

31 March 2020

12 December 2020

A ubiquitin ligase complex assembles linear polyubiquitin chains

2 references

31 March 2020

12 December 2020

Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series

2 references

31 March 2020

12 December 2020

Nonproteolytic functions of ubiquitin in cell signaling

2 references

31 March 2020

12 December 2020

Ubiquitin-binding domains - from structures to functions

2 references

31 March 2020

12 December 2020

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

2 references

31 March 2020

12 December 2020

Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain

2 references

31 March 2020

12 December 2020

Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80

2 references

31 March 2020

12 December 2020

Toward maintaining the genome: DNA damage and replication checkpoints

2 references

31 March 2020

12 December 2020

Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp.

2 references

31 March 2020

12 December 2020

Quality control by DNA repair

2 references

31 March 2020

12 December 2020

Principles of ubiquitin and SUMO modifications in DNA repair.

2 references

31 March 2020

12 December 2020

Regulation of DNA repair by ubiquitylation

2 references

31 March 2020

12 December 2020

Checkpoint signaling from a single DNA interstrand crosslink

2 references

31 March 2020

12 December 2020

The RAD6 DNA repair pathway in Saccharomyces cerevisiae: what does it do, and how does it do it?

2 references

31 March 2020

12 December 2020

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

2 references

31 March 2020

12 December 2020

MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals

2 references

31 March 2020

12 December 2020

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

2 references

31 March 2020

12 December 2020

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

2 references

31 March 2020

12 December 2020

Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

2 references

31 March 2020

12 December 2020

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

2 references

31 March 2020

12 December 2020

Noncanonical E2 variant-independent function of UBC13 in promoting checkpoint protein assembly

2 references

31 March 2020

12 December 2020

A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination

2 references

31 March 2020

12 December 2020

The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage

2 references

31 March 2020

12 December 2020

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

2 references

31 March 2020

12 December 2020

Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response

2 references

31 March 2020

12 December 2020

CCDC98 targets BRCA1 to DNA damage sites

2 references

31 March 2020

12 December 2020

RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites

2 references

31 March 2020

12 December 2020

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

2 references

31 March 2020

12 December 2020

MERIT40 facilitates BRCA1 localization and DNA damage repair

2 references

31 March 2020

12 December 2020

MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks

2 references

31 March 2020

12 December 2020

NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control

2 references

31 March 2020

12 December 2020

RAD18 transmits DNA damage signalling to elicit homologous recombination repair

2 references

31 March 2020

12 December 2020

HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

2 references

31 March 2020

12 December 2020

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

2 references

31 March 2020

12 December 2020

Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

2 references

31 March 2020

12 December 2020

Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer

2 references

31 March 2020

12 December 2020

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

2 references

31 March 2020

12 December 2020

The many faces of ubiquitinated histone H2A: insights from the DUBs

2 references

31 March 2020

12 December 2020

Human USP3 is a chromatin modifier required for S phase progression and genome stability

2 references

31 March 2020

12 December 2020

Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

2 references

31 March 2020

12 December 2020

The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress.

2 references

31 March 2020

12 December 2020

BRCA1 and its toolbox for the maintenance of genome integrity

2 references

31 March 2020

12 December 2020

RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling

2 references

31 March 2020

12 December 2020

Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

2 references

31 March 2020

12 December 2020

A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses

2 references

31 March 2020

12 December 2020

The fanconi anemia core complex acts as a transcriptional co-regulator in hairy enhancer of split 1 signaling.

2 references

31 March 2020

12 December 2020

HES1 is a novel interactor of the Fanconi anemia core complex

2 references

31 March 2020

12 December 2020

Monoubiquitylation in the Fanconi anemia DNA damage response pathway

2 references

31 March 2020

12 December 2020

How the fanconi anemia pathway guards the genome

2 references

31 March 2020

12 December 2020

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

2 references

31 March 2020

12 December 2020

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

2 references

31 March 2020

12 December 2020

A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M

2 references

31 March 2020

12 December 2020

Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24.

2 references

31 March 2020

12 December 2020

Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM.

2 references

31 March 2020

12 December 2020

FANCM of the Fanconi anemia core complex is required for both monoubiquitination and DNA repair

2 references

31 March 2020

12 December 2020

FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia

2 references

31 March 2020

12 December 2020

ATR activation and replication fork restart are defective in FANCM-deficient cells

2 references

31 March 2020

12 December 2020

FANCM regulates DNA chain elongation and is stabilized by S-phase checkpoint signalling

2 references

31 March 2020

12 December 2020

MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM

2 references

31 March 2020

12 December 2020

A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability

2 references

31 March 2020

12 December 2020

A novel ubiquitin ligase is deficient in Fanconi anemia

2 references

31 March 2020

12 December 2020

UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation

2 references

31 March 2020

12 December 2020

Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI

2 references

31 March 2020

12 December 2020

FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway

2 references

31 March 2020

12 December 2020

FANCI binds branched DNA and is monoubiquitinated by UBE2T-FANCL

2 references

31 March 2020

12 December 2020

The structure of the catalytic subunit FANCL of the Fanconi anemia core complex

2 references

31 March 2020

12 December 2020

Ubiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells

2 references

31 March 2020

12 December 2020

A FancD2-monoubiquitin fusion reveals hidden functions of Fanconi anemia core complex in DNA repair

2 references

31 March 2020

12 December 2020

The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair

2 references

31 March 2020

12 December 2020

Mechanism of replication-coupled DNA interstrand crosslink repair

2 references

31 March 2020

12 December 2020

Deubiquitination of FANCD2 is required for DNA crosslink repair

2 references

31 March 2020

12 December 2020

The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway

2 references

31 March 2020

12 December 2020

Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype.

2 references

31 March 2020

12 December 2020

FANCD2 hurdles the DNA interstrand crosslink

2 references

31 March 2020

12 December 2020

TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells.

2 references

31 March 2020

12 December 2020

Regulating post-translational modifications of the eukaryotic replication clamp PCNA.

2 references

31 March 2020

12 December 2020

RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

2 references

31 March 2020

12 December 2020

Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage

2 references

31 March 2020

12 December 2020

Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination

2 references

31 March 2020

12 December 2020

Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation

2 references

31 March 2020

12 December 2020

Genetic analysis of ionizing radiation-induced mutagenesis in Saccharomyces cerevisiae reveals TransLesion Synthesis (TLS) independent of PCNA K164 SUMOylation and ubiquitination

2 references

31 March 2020

12 December 2020

PCNA ubiquitination and REV1 define temporally distinct mechanisms for controlling translesion synthesis in the avian cell line DT40.

2 references

31 March 2020

12 December 2020

Involvement of vertebrate polkappa in Rad18-independent postreplication repair of UV damage

2 references

31 March 2020

12 December 2020

A role for PCNA ubiquitination in immunoglobulin hypermutation

2 references

31 March 2020

12 December 2020

Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis

2 references

31 March 2020

12 December 2020

RAD6-RAD18-RAD5-pathway-dependent tolerance to chronic low-dose ultraviolet light.

2 references

31 March 2020

12 December 2020

Distinct consequences of posttranslational modification by linear versus K63-linked polyubiquitin chains

2 references

31 March 2020

12 December 2020

Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p

2 references

31 March 2020

12 December 2020

SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase

2 references

31 March 2020

12 December 2020

PCNA controls establishment of sister chromatid cohesion during S phase

2 references

31 March 2020

12 December 2020

Ubiquitinated proliferating cell nuclear antigen activates translesion DNA polymerases eta and REV1

2 references

31 March 2020

12 December 2020

SUMO modification of PCNA is controlled by DNA.

2 references

31 March 2020

12 December 2020

Synthesis of free and proliferating cell nuclear antigen-bound polyubiquitin chains by the RING E3 ubiquitin ligase Rad5.

2 references

31 March 2020

12 December 2020

Mechanistic analysis of PCNA poly-ubiquitylation by the ubiquitin protein ligases Rad18 and Rad5.

2 references

31 March 2020

12 December 2020

Activation of ubiquitin-dependent DNA damage bypass is mediated by replication protein a.

2 references

31 March 2020

12 December 2020

Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells

2 references

31 March 2020

12 December 2020

Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires uncoupling of DNA polymerase and mini-chromosome maintenance helicase activities.

2 references

31 March 2020

12 December 2020

Postreplication repair and PCNA modification in Schizosaccharomyces pombe

2 references

31 March 2020

12 December 2020

The RAD6 DNA damage tolerance pathway operates uncoupled from the replication fork and is functional beyond S phase.

2 references

31 March 2020

12 December 2020

The critical mutagenic translesion DNA polymerase Rev1 is highly expressed during G(2)/M phase rather than S phase

2 references

31 March 2020

12 December 2020

Chk1 and Claspin potentiate PCNA ubiquitination

2 references

31 March 2020

12 December 2020

Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest

2 references

31 March 2020

12 December 2020

RAD18-independent ubiquitination of proliferating-cell nuclear antigen in the avian cell line DT40.

2 references

31 March 2020

12 December 2020

CRL4(Cdt2) E3 ubiquitin ligase monoubiquitinates PCNA to promote translesion DNA synthesis

2 references

31 March 2020

12 December 2020

PCNA is ubiquitinated by RNF8

2 references

31 March 2020

12 December 2020

Defects in DNA ligase I trigger PCNA ubiquitylation at Lys 107.

2 references

31 March 2020

12 December 2020

Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis.

2 references

31 March 2020

12 December 2020

Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange

2 references

31 March 2020

12 December 2020

The origins of protein phosphorylation

2 references

31 March 2020

12 December 2020

Historical review: the field of protein methylation

2 references

31 March 2020

12 December 2020

Biochemical pathways that regulate acetyltransferase and deacetylase activity in mammalian cells

2 references

31 March 2020

12 December 2020

E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages

2 references

31 March 2020

12 December 2020

BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP

2 references

31 March 2020

12 December 2020

E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks

2 references

31 March 2020

12 December 2020

PALB2 is an integral component of the BRCA complex required for homologous recombination repair

2 references

31 March 2020

12 December 2020

PALB2 links BRCA1 and BRCA2 in the DNA-damage response

2 references

31 March 2020

12 December 2020

Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins

2 references

31 March 2020

12 December 2020

Role for RAD18 in homologous recombination in DT40 cells.

2 references

31 March 2020

12 December 2020

Genetic analysis of gamma-ray mutagenesis in yeast. III. Double-mutant strains

2 references

31 March 2020

12 December 2020

Ubiquitylation of the 9-1-1 checkpoint clamp is independent of rad6-rad18 and DNA damage

1 reference

12 December 2020

Ubiquitin-dependent DNA damage bypass is separable from genome replication

1 reference

12 December 2020

Regulation of monoubiquitinated PCNA by DUB autocleavage

1 reference

12 December 2020

To cell cycle, swing the APC/C.

1 reference

12 December 2020