(Q64056230)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31193016%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

title

The Impact of Pre-existing Immunity on the Non-clinical Pharmacodynamics of AAV5-Based Gene Therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31193016%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

1 reference

Krystal Sandza

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31193016%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Jennifer Holcomb

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31193016%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Lucy Crockett

4

1 reference

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1 May 2020

Jeremy Arens

6

1 reference

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1 May 2020

Carlos Fonck

7

1 reference

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1 May 2020

Becky Schweighardt

9

1 reference

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1 May 2020

Stephen Zoog

11

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1 May 2020

Christian Vettermann

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31193016%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Brian R Long

1

1 reference

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1 May 2020

Gregory M Hayes

5

1 reference

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1 May 2020

Laurie S Tsuruda

8

1 reference

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1 May 2020

Charles A O'Neill

10

1 reference

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1 May 2020

publication date

11 April 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31193016%20AND%20SRC:MED&resulttype=core&format=json

Molecular Therapy. Methods & Clinical Development

1 May 2020

published in

1 reference

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1 May 2020

volume

13

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1 May 2020

page(s)

440-452

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31193016%20AND%20SRC:MED&resulttype=core&format=json

Adeno-associated virus vectors for gene therapy

1 May 2020

cites work

1 reference

12 December 2020

Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors

1 reference

12 December 2020

Cloning and characterization of adeno-associated virus type 5.

1 reference

12 December 2020

Inhibition of recombinant adeno-associated virus (rAAV) transduction by bronchial secretions from cystic fibrosis patients

1 reference

12 December 2020

Clades of Adeno-associated viruses are widely disseminated in human tissues.

1 reference

12 December 2020

Comparison of the ability of adeno-associated viral vectors pseudotyped with serotype 2, 5, and 8 capsid proteins to mediate efficient transduction of the liver in murine and nonhuman primate models

1 reference

12 December 2020

Novel caprine adeno-associated virus (AAV) capsid (AAV-Go.1) is closely related to the primate AAV-5 and has unique tropism and neutralization properties

1 reference

12 December 2020

Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver

1 reference

12 December 2020

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

1 reference

12 December 2020

Effects of transient immunosuppression on adenoassociated, virus-mediated, liver-directed gene transfer in rhesus macaques and implications for human gene therapy

1 reference

12 December 2020

Alpha2,3 and alpha2,6 N-linked sialic acids facilitate efficient binding and transduction by adeno-associated virus types 1 and 6

1 reference

12 December 2020

Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates

1 reference

12 December 2020

1 reference

12 December 2020

Effect of inhibition of dynein function and microtubule-altering drugs on AAV2 transduction.

1 reference

12 December 2020

Worldwide epidemiology of neutralizing antibodies to adeno-associated viruses.

1 reference

12 December 2020

Prevalence of serum IgG and neutralizing factors against adeno-associated virus (AAV) types 1, 2, 5, 6, 8, and 9 in the healthy population: implications for gene therapy using AAV vectors

1 reference

12 December 2020

Long-term safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteins.

1 reference

12 December 2020

Neutralizing antibodies against adeno-associated virus examined prospectively in pediatric patients with hemophilia

1 reference

12 December 2020

Adenovirus-associated virus vector-mediated gene transfer in hemophilia B

1 reference

12 December 2020

Intracellular transport of recombinant adeno-associated virus vectors

1 reference

12 December 2020

Guidelines for the management of hemophilia

1 reference

12 December 2020

Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant

1 reference

12 December 2020

Pre-existing anti-adeno-associated virus antibodies as a challenge in AAV gene therapy

1 reference

12 December 2020

Humoral immunity to AAV vectors in gene therapy: challenges and potential solutions

1 reference

12 December 2020

The prevalence of neutralizing antibodies against adeno-associated virus capsids is reduced in young Japanese individuals

1 reference

12 December 2020

New FDA draft guidance on immunogenicity

1 reference

12 December 2020

Neutralizing antibodies against AAV2, AAV5 and AAV8 in healthy and HIV-1-infected subjects in China: implications for gene therapy using AAV vectors

1 reference

12 December 2020

Recombinant adeno-associated virus utilizes cell-specific infectious entry mechanisms

1 reference

12 December 2020

Successful Phenotype Improvement following Gene Therapy for Severe Hemophilia A in Privately Owned Dogs.

1 reference

12 December 2020

AAV Natural Infection Induces Broad Cross-Neutralizing Antibody Responses to Multiple AAV Serotypes in Chimpanzees

1 reference

12 December 2020

Direct interaction of human serum proteins with AAV virions to enhance AAV transduction: immediate impact on clinical applications

1 reference

12 December 2020

Neutralizing antibodies against adeno-associated viruses in Sjögren's patients: implications for gene therapy

1 reference

12 December 2020

Differential Prevalence of Antibodies Against Adeno-Associated Virus in Healthy Children and Patients with Mucopolysaccharidosis III: Perspective for AAV-Mediated Gene Therapy.

1 reference

12 December 2020

Differential prevalence of antibodies against adeno-associated virus in healthy children and patients with mucopolysaccharidosis III: perspective for AAV-mediated gene therapy

1 reference

12 December 2020

Strategy to detect pre-existing immunity to AAV gene therapy.

1 reference

12 December 2020

Hemophilia B Gene Therapy with a High-Specific-Activity Factor IX Variant.

1 reference

12 December 2020

AAV5-Factor VIII Gene Transfer in Severe Hemophilia A.

1 reference

12 December 2020

10.1016/J.OMTM.2019.03.006

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31193016%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31193016%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

PubMed publication ID

31193016

1 reference