(Q64254345)

English

Histone deacetylase inhibitors suppress aggressiveness of head and neck squamous cell carcinoma via histone acetylation-independent blockade of the EGFR-Arf1 axis

scientific article published on 18 February 2019

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30777099%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Histone deacetylase inhibitors suppress aggressiveness of head and neck squamous cell carcinoma via histone acetylation-independent blockade of the EGFR-Arf1 axis (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30777099%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

HDAC [nucleoplasm]

0 references

head and neck squamous cell carcinoma

1 reference

based on heuristic

inferred from title

histone acetylation

1 reference

based on heuristic

inferred from title

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30777099%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

author name string

Leilei He

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30777099%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Lixia Gao

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30777099%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Chloe Shay

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30777099%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Liwei Lang

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30777099%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Fenglin Lv

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30777099%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

language of work or name

0 references

publication date

18 February 2019

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30777099%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Journal of Experimental & Clinical Cancer Research

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30777099%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

38

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30777099%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30777099%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

84

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30777099%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

copyright license

Creative Commons Attribution 4.0 International

18 February 2019

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

https://scigraph.springernature.com/pub.10.1186/s13046-019-1080-8

0 references

Elevated levels of transforming growth factor alpha and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tyrosine kinase Pyk2 regulates Arf1 activity by phosphorylation and inhibition of the Arf-GTPase-activating protein ASAP1

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor biology in head and neck cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetic aberrations and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ADP-ribosylation factor 1 controls the activation of the phosphatidylinositol 3-kinase pathway to regulate epidermal growth factor-dependent growth and migration of breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular target approaches in head and neck cancer: epidermal growth factor receptor and beyond

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of histone deacetylases (HDACs) in human cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGFR signaling suppresses osteoblast differentiation and inhibits expression of master osteoblastic transcription factors Runx2 and Osterix.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HDAC inhibition decreases the expression of EGFR in colorectal cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylase inhibitors: emerging mechanisms of resistance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HSP90 and HSP70 proteins are essential for stabilization and activation of WASF3 metastasis-promoting protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complexity in the signaling network: insights from the use of targeted inhibitors in cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer epigenetics: from mechanism to therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HDAC inhibitors augmented cell migration and metastasis through induction of PKCs leading to identification of low toxicity modalities for combination cancer therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting histone modifications--epigenetics in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of histone deacetylase impacts cancer stem cells and induces epithelial-mesenchyme transition of head and neck cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The HDAC inhibitor, MPT0E028, enhances erlotinib-induced cell death in EGFR-TKI-resistant NSCLC cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ARF1 regulates the Rho/MLC pathway to control EGF-dependent breast cancer cell invasion

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The adaptor proteins p66Shc and Grb2 regulate the activation of the GTPases ARF1 and ARF6 in invasive breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical update on cancer: molecular oncology of head and neck cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erasers of histone acetylation: the histone deacetylase enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

WASF3 provides the conduit to facilitate invasion and metastasis in breast cancer cells through HER2/HER3 signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone Deacetylase-3/CAGE Axis Targets EGFR Signaling and Regulates the Response to Anti-Cancer Drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of histone deacetylases in cancer therapy: lessons from leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ARF1 promotes prostate tumorigenesis via targeting oncogenic MAPK signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The WASF3-NCKAP1-CYFIP1 Complex Is Essential for Breast Cancer Metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic Alteration in Head and Neck Squamous Cell Carcinoma (HNSCC) Cell Lines Inferred from Karyotyping, Molecular Cytogenetics, and Array Comparative Genomic Hybridization.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of breast cancer metastasis through the inactivation of ADP-ribosylation factor 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HDACs and HDAC Inhibitors in Cancer Development and Therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combined targeting of Arf1 and Ras potentiates anticancer activity for prostate cancer therapeutics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FGF19 Protects Hepatocellular Carcinoma Cells against Endoplasmic Reticulum Stress via Activation of FGFR4-GSK3β-Nrf2 Signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combating head and neck cancer metastases by targeting Src using multifunctional nanoparticle-based saracatinib.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy blockade sensitizes human head and neck squamous cell carcinoma towards CYT997 through enhancing excessively high reactive oxygen species-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30777099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S13046-019-1080-8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30777099%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30777099%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30777099%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

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