(Q64270478)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30726737%20AND%20SRC:MED&resulttype=core&format=json

22 April 2020

title

A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30726737%20AND%20SRC:MED&resulttype=core&format=json

22 April 2020

0 references

1 reference

2

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22 April 2020

Jan E Carette

12

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22 April 2020

author name string

Jennifer Yinuo Cao

1

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22 April 2020

Leslie Magtanong

3

1 reference

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22 April 2020

Jennifer H Lumb

4

1 reference

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22 April 2020

Trevor R Mileur

5

1 reference

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22 April 2020

Michael A Reid

6

1 reference

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22 April 2020

Cole M Dovey

7

1 reference

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22 April 2020

Jin Wang

8

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22 April 2020

Jason W Locasale

9

1 reference

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22 April 2020

Everett Stone

10

1 reference

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22 April 2020

Susan P C Cole

11

1 reference

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22 April 2020

Scott J Dixon

13

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22 April 2020

language of work or name

English

0 references

publication date

1 February 2019

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22 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30726737%20AND%20SRC:MED&resulttype=core&format=json

22 April 2020

volume

26

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22 April 2020

issue

6

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22 April 2020

page(s)

1544-1556.e8

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describes a project that uses

22 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6424331/fullTextXML

inferred from PubMed Central ID database lookup

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Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo

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Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity

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Verapamil and its derivative trigger apoptosis through glutathione extrusion by multidrug resistance protein MRP1.

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SLCO/OATP-like transport of glutathione in FasL-induced apoptosis: glutathione efflux is coupled to an organic anion exchange and is necessary for the progression of the execution phase of apoptosis.

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Glutathione export during apoptosis requires functional multidrug resistance-associated proteins

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12 December 2020

Multidrug resistance-associated protein 1 as a major mediator of basal and apoptotic glutathione release

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12 December 2020

Molecular basis for reduced estrone sulfate transport and altered modulator sensitivity of transmembrane helix (TM) 6 and TM17 mutants of multidrug resistance protein 1 (ABCC1).

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12 December 2020

High-throughput profiling of amino acids in strains of the Saccharomyces cerevisiae deletion collection

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12 December 2020

Global gene disruption in human cells to assign genes to phenotypes by deep sequencing

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12 December 2020

Ebola virus entry requires the cholesterol transporter Niemann-Pick C1

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12 December 2020

PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function

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12 December 2020

Cellular metabolism and disease: what do metabolic outliers teach us?

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12 December 2020

Ferroptosis: an iron-dependent form of nonapoptotic cell death

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12 December 2020

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12 December 2020

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12 December 2020

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Nrf2 pathway regulates multidrug-resistance-associated protein 1 in small cell lung cancer

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Development and quantitative evaluation of a high-resolution metabolomics technology

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12 December 2020

Regulation of ferroptotic cancer cell death by GPX4

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12 December 2020

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis

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12 December 2020

Multidrug resistance protein 1 (MRP1, ABCC1), a "multitasking" ATP-binding cassette (ABC) transporter

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12 December 2020

Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression

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12 December 2020

Molecular, cellular, and physiological significance of N-terminal acetylation.

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12 December 2020

Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death

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12 December 2020

Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

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12 December 2020

Oxidative stress inhibits distant metastasis by human melanoma cells

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12 December 2020

Correlating chemical sensitivity and basal gene expression reveals mechanism of action.

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12 December 2020

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12 December 2020

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12 December 2020

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MRP1-dependent Collateral Sensitivity of Multidrug-resistant Cancer Cells: Identifying Selective Modulators Inducing Cellular Glutathione Depletion.

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12 December 2020

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12 December 2020

Nrf2 inhibition reverses the resistance of cisplatin-resistant head and neck cancer cells to artesunate-induced ferroptosis

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product.

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12 December 2020

Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer

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12 December 2020

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

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12 December 2020

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition.

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12 December 2020

Heme oxygenase-1 mediates BAY 11-7085 induced ferroptosis.

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12 December 2020

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12 December 2020

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12 December 2020

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Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State

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12 December 2020

10.1016/J.CELREP.2019.01.043

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30726737%20AND%20SRC:MED&resulttype=core&format=json

22 April 2020

1 reference

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22 April 2020

1 reference