(Q64362388)

English

Defective integration of activating signals derived from the T cell receptor (TCR) and costimulatory molecules in both CD4+ and CD8+ T lymphocytes of common variable immunodeficiency (CVID) patients

scholarly article by V Thon et al published November 1997 in Clinical and Experimental Immunology

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scholarly article

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Defective integration of activating signals derived from the T cell receptor (TCR) and costimulatory molecules in both CD4+ and CD8+ T lymphocytes of common variable immunodeficiency (CVID) patients (English)

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common variable immunodeficiency

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inferred from title

1

subject named as

V Thon

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Hermann Maximilian Wolf

2

subject named as

H M Wolf

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8

subject named as

M M Eibl

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author name string

M Sasgary

3

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J Litzman

4

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A Samstag

5

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I Hauber

6

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J Lokaj

7

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language of work or name

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publication date

November 1997

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Clinical and Experimental Immunology

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110

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2

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174-81

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Role of suppressor T cells in pathogenesis of common variable hypogammaglobulinaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation via the antigen receptor is impaired in T cells, but not in B cells from patients with common variable immunodeficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The T cell dependence of B cell differentiation induced by pokeweed mitogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative measurements of T- and B-cell function in "variable" primary hypogammaglobulinaemia: evidence for a consistent B-cell defect

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormalities of lymphokine gene expression in patients with common variable immunodeficiency.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell receptors: adhesion and signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defects in proliferative responses of T cells from patients with common variable immunodeficiency on direct activation of protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of CD4 following phorbol-induced internalization in human T lymphocytes. Evidence for distinct endocytic routing of CD4 and CD3

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B cells from subjects with CVI can be driven to Ig production in response to CD40 stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of T-cell lymphokine gene transcription by the accessory molecule CD28

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell co-stimulatory activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced lymphokine production and lymphokine receptor expression in multiple antibody-stimulated human CD4+ peripheral blood lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell abnormalities in common variable immunodeficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective expression of the CD40 ligand in X chromosome-linked immunoglobulin deficiency with normal or elevated IgM

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common variable immunodeficiency: how many diseases?

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional abnormalities of CD8+ T cells define a unique subset of patients with common variable immunodeficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective interleukin-2 and interferon-gamma gene expression in response to antigen in a subgroup of patients with common variable immunodeficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated B cells from patients with common variable immunodeficiency proliferate and synthesize immunoglobulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced interleukin-2 (IL-2) production in common variable immunodeficiency is due to a primary abnormality of CD4+ T cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signals and signs for lymphocyte responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 ligand expression is defective in a subset of patients with common variable immunodeficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-stimulation with anti-CD28 (Kolt-2) enhances DNA synthesis by defective T cells in common variable immunodeficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The costimulatory signal CD28 is fully functional but cannot correct the impaired antigen response in T cells of patients with common variable immunodeficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of RNA using the polymerase chain reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genetic basis of immunoglobulin-class switching

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of p21ras activation in T cell CD69 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclosporin A inhibits CD40 ligand expression in T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Failure in antigen responses by T cells from patients with common variable immunodeficiency (CVID).

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient induction of immunoglobulin production in neonatal naive B cells by memory CD4+ T cell subset expressing homing receptor L-selectin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Costimulation through CD28 enhances T cell-dependent B cell activation via CD40-CD40L interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B cell differentiation defects in common variable immunodeficiency are ameliorated after stimulation with anti-CD40 antibody and IL-10

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of CD40 in the regulation of humoral and cell-mediated immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A defect in the early phase of T-cell receptor-mediated T-cell activation in patients with common variable immunodeficiency.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The regulation and function of p21ras during T-cell activation and growth.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 and its ligand: central players in B lymphocyte survival, growth, and differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the CD40 ligand in T lymphocytes and induction of IgE isotype switching

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defects in antigen-driven lymphocyte responses in common variable immunodeficiency (CVID) are due to a reduction in the number of antigen-specific CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of gp39 (CD40L) in immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulation of the IL-2 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular immunoglobulin production in vitro by lymphocytes from patients with hypogammaglobulinaemia and their effect on normal lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9367399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2249.1997.TB08314.X

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