(Q64379556)

2

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R V Gopalkrishnan

3

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N I Goldstein

4

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C A Stein

5

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J C Reed

6

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P Dent

7

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P B Fisher

Proceedings of the National Academy of Sciences of the United States of America

8

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language of work or name

English

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publication date

28 August 2001

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published in

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volume

98

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page(s)

10332-7

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issue

18

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cites work

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Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced ce

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Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

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The dominant negative H-ras mutant, N116Y, suppresses growth of metastatic human pancreatic cancer cells in the liver of nude mice

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Regional chemotherapy in the treatment of advanced pancreatic cancer--is it relevant?

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The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice

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Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro

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Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

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Treatment of advanced and metastatic pancreatic cancer

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The Ras branch of small GTPases: Ras family members don't fall far from the tree

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The Ras/phosphatidylinositol 3-kinase and Ras/ERK pathways function as independent survival modules each of which inhibits a distinct apoptotic signaling pathway in sympathetic neurons.

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Mda-7, a novel melanoma differentiation associated gene with promise for cancer gene therapy

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Mitochondria and apoptosis

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Inhibition of colon cancer cell proliferation by antisense oligonucleotides targeting the messenger RNA of the Ki-ras gene.

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The genetic analysis of recombination using adenovirus overlapping terminal DNA fragments

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What is the true rate of K-ras mutation in carcinoma of the pancreas?

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Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

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Molecular aspects of pancreatic cancer and future perspectives

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Molecular genetic basis of pancreatic adenocarcinoma

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Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

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Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression

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Liposome-mediated in vivo gene transfer of antisense K-ras construct inhibits pancreatic tumor dissemination in the murine peritoneal cavity

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Bcl-xL in prostate cancer cells: effects of overexpression and down-regulation on chemosensitivity

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Mechanisms of apoptosis

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Transcriptional switching model for the regulation of tumorigenesis and metastasis by the ha-ras oncogene - transcriptional changes in the ha-ras tumor-suppressor gene lysyl oxidase.

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The molecular and cellular biology of pancreatic cancer

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Effects of combined treatment with interferon and mezerein on melanogenesis and growth in human melanoma cells

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The melanoma differentiation associated gene mda-7 suppresses cancer cell growth

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Adjuvant therapy for pancreatic cancer: current status

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Ki-ras oncogene activation in preinvasive pancreatic cancer

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Melanoma differentiation associated gene-7 (mda-7): a novel anti-tumor gene for cancer gene therapy

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Antisense oligonucleotides as therapeutic agents--is the bullet really magical?

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Pancreatic cancer: a review of emerging therapies

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Apoptosis mediates the selective toxicity of caffeic acid phenethyl ester (CAPE) toward oncogene-transformed rat embryo fibroblast cells

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Growth inhibition of human pancreatic cancer cell lines by anti-sense oligonucleotides specific to mutated K-ras genes

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Suppression of Ki-ras p21 levels leading to growth inhibition of pancreatic cancer cell lines with Ki-ras mutation but not those without Ki-ras mutation

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12 December 2020

PI-3-kinase is an essential anti-apoptotic effector in the proliferative response of primary human epithelial cells to mutant RAS

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12 December 2020

Phosphorothioate antisense oligodeoxynucleotides: questions of specificity

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BCL-2 family members and the mitochondria in apoptosis

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Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase

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Tumor-suppressive effects by adenovirus-mediated mda-7 gene transfer in non-small cell lung cancer cell in vitro

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Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

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