(Q64388891)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10329701%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

title

DNA-dependent protein kinase protects against heat-induced apoptosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10329701%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

author name string

A Nueda

1

1 reference

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8 December 2019

F Hudson

2

1 reference

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8 December 2019

N F Mivechi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10329701%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

W S Dynan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10329701%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

language of work or name

English

0 references

publication date

1 May 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10329701%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

8 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10329701%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

volume

274

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10329701%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

issue

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10329701%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

page(s)

14988-14996

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10329701%20AND%20SRC:MED&resulttype=core&format=json

Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II

8 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Double strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Double-strand break repair mediated by DNA end-joining.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Stimulation of the DNA-dependent protein kinase by poly(ADP-ribose) polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

DNA-dependent protein kinase phosphorylation of IkappaB alpha and IkappaB beta regulates NF-kappaB DNA binding properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

p95vav associates with the nuclear protein Ku-70

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Functional interaction between DNA-PK and c-Abl in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Stimulation of the DNA-dependent protein kinase by RNA polymerase II transcriptional activator proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Heat shock transcription factor 1 binds selectively in vitro to Ku protein and the catalytic subunit of the DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Modulation of thermal induction of hsp70 expression by Ku autoantigen or its individual subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Suppression of heat-induced hsp70 expression by the 70-kDa subunit of the human Ku autoantigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

A constitutive heat shock element-binding factor is immunologically identical to the Ku autoantigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Sequence-specific DNA binding and transcription factor phosphorylation by Ku Autoantigen/DNA-dependent protein kinase. Phosphorylation of Ser-527 of the rat glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Thermal sensitivity and the effect of elevated temperatures on the radiation sensitivity of Chinese hamster cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Thermally enhanced radioresponse of cultured Chinese hamster cells: inhibition of repair of sublethal damage and enhancement of lethal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Interaction of hyperthermia and radiation in CHO cells: recovery kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

A DNA double-strand break repair-deficient mutant of CHO cells shows reduced radiosensitization after exposure to hyperthermic temperatures in the plateau phase of growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Thermal response and hyperthermic radiosensitization of scid mouse bone marrow CFU-C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

A possible mechanism for hyperthermic radiosensitization mediated through hyperthermic lability of Ku subunits in DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Induction of sequence-specific binding of Drosophila heat shock activator protein without protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Regulated expression of p150,95 (CD11c/CD18; alpha X/beta 2) and VLA-4 (CD49d/CD29; alpha 4/beta 1) integrins during myeloid cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

A human gene that restores the DNA-repair defect in SCID mice is located on 8p11.1-->q11.1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

X-ray-sensitive mutants of Chinese hamster ovary cell line isolation and cross-sensitivity to other DNA-damaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Molecular and biochemical characterization of xrs mutants defective in Ku80.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Disruption of DNA-PK in Ku80 mutant xrs-6 and the implications in DNA double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Hyperthermia Induces Apoptosis in Thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

The Role of Apoptosis in the Response of Cells and Tumours to Mild Hyperthermia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

DNA lesions in hyperthermic cell killing: effects of thermotolerance, procaine, and erythritol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Cell death induced in a murine mastocytoma by 42-47 degrees C heating in vitro: evidence that the form of death changes from apoptosis to necrosis above a critical heat load.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Characterization and sequence of a mouse hsp70 gene and its expression in mouse cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Sequence and organization of genes encoding the human 27 kDa heat shock protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

21 January 2018

The heat-shock response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

The effects of hyperthermia on mammalian cell structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

DNA binding of heat shock factor to the heat shock element is insufficient for transcriptional activation in murine erythroleukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Methylation-associated transcriptional silencing of the major histocompatibility complex-linked hsp70 genes in mouse cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

DNA damage production in CHO cells at elevated temperatures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Analysis by pulsed-field gel electrophoresis of DNA double-strand breaks induced by heat and/or X-irradiation in bulk and replicating DNA of CHO cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

DNA double-strand-break sensitivity, DNA replication, and cell cycle arrest phenotypes of Ku-deficient Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Stable overexpression of human HSF-1 in murine cells suggests activation rather than expression of HSF-1 to be the key regulatory step in the heat shock gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Repression of the heat shock factor 1 transcriptional activation domain is modulated by constitutive phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Repression of human heat shock factor 1 activity at control temperature by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Sequential phosphorylation by mitogen-activated protein kinase and glycogen synthase kinase 3 represses transcriptional activation by heat shock factor-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Analysis of the phosphorylation of human heat shock transcription factor-1 by MAP kinase family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Glycogen synthase kinase 3beta and extracellular signal-regulated kinase inactivate heat shock transcription factor 1 by facilitating the disappearance of transcriptionally active granules after heat shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

The Elk-1 ETS-domain transcription factor contains a mitogen-activated protein kinase targeting motif.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Ceramide formation during heat shock: a potential mediator of alpha B-crystallin transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.21.14988

21 January 2018

Identifiers

DOI

10.1074/JBC.274.21.14988

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10329701%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference