(Q64864377)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

title

Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Makoto Nakakido

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Satoru Nagatoishi

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Noriyuki Matsuda

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Dali Liu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

author name string

Shinya Tashiro

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Aki Tanabe

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Yasushi Tamura

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Quyen Q Hoang

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Kouhei Tsumoto

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

publication date

15 August 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

page(s)

2783-2793

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

15 April 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6370461/fullTextXML

inferred from PubMed Central ID database lookup

cites work

A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

1 reference

12 December 2020

Isatin: Identity with the Purified Endogenous Monoamine Oxidase Inhibitor Tribulin

1 reference

12 December 2020

Design, synthesis, and evaluation of nonpeptidic inhibitors of human rhinovirus 3C protease

1 reference

12 December 2020

DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras

1 reference

12 December 2020

Enhanced phosphorylation of p53 by ATM in response to DNA damage

1 reference

12 December 2020

[Pharmacological role of isatin, an endogenous MAO inhibitor]

1 reference

12 December 2020

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

1 reference

12 December 2020

Crystal structure of human DJ-1, a protein associated with early onset Parkinson's disease

1 reference

12 December 2020

The crystal structure of DJ-1, a protein related to male fertility and Parkinson's disease

1 reference

12 December 2020

The 1.1-A resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease

1 reference

12 December 2020

Insights into the mode of inhibition of human mitochondrial monoamine oxidase B from high-resolution crystal structures

1 reference

12 December 2020

Crystal structure of DJ-1/RS and implication on familial Parkinson's disease

1 reference

12 December 2020

Crystal structures of human DJ-1 and Escherichia coli Hsp31, which share an evolutionarily conserved domain

1 reference

12 December 2020

Evolutionary and functional relationships within the DJ1 superfamily

1 reference

12 December 2020

Differential control of apoptosis by DJ-1 in prostate benign and cancer cells

1 reference

12 December 2020

PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

1 reference

12 December 2020

Monoamine oxidases: certainties and uncertainties

1 reference

12 December 2020

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

12 December 2020

Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism

1 reference

12 December 2020

DJ-1, a novel regulator of the tumor suppressor PTEN.

1 reference

12 December 2020

Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.

1 reference

12 December 2020

Isatin: role in stress and anxiety

1 reference

12 December 2020

Scaling and assessment of data quality

1 reference

12 December 2020

The therapeutic potential of monoamine oxidase inhibitors

1 reference

12 December 2020

An investigation into the cytotoxicity and mode of action of some novel N-alkyl-substituted isatins.

1 reference

12 December 2020

Fluorine in pharmaceuticals: looking beyond intuition

1 reference

12 December 2020

Expression and clinical role of DJ-1, a negative regulator of PTEN, in ovarian carcinoma

1 reference

12 December 2020

N-phenethyl and N-naphthylmethyl isatins and analogues as in vitro cytotoxic agents.

1 reference

12 December 2020

Covalent radii revisited

1 reference

12 December 2020

Cysteine p K a Depression by a Protonated Glutamic Acid in Human DJ-1

1 reference

12 December 2020

Expression and role of DJ-1 in leukemia

1 reference

12 December 2020

Formation of a Stabilized Cysteine Sulfinic Acid Is Critical for the Mitochondrial Function of the Parkinsonism Protein DJ-1

1 reference

12 December 2020

Contributions of interfacial residues of human Interleukin15 to the specificity and affinity for its private alpha-receptor.

1 reference

12 December 2020

Cytotoxic and anticancer activities of isatin and its derivatives: a comprehensive review from 2000-2008.

1 reference

12 December 2020

Phasercrystallographic software

1 reference

12 December 2020

Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase

1 reference

12 December 2020

Adding calorimetric data to decision making in lead discovery: a hot tip

1 reference

12 December 2020

QSAR study of isatin analogues as in vitro anti-cancer agents

1 reference

12 December 2020

Parkinson disease protein DJ-1 converts from a zymogen to a protease by carboxyl-terminal cleavage

1 reference

12 December 2020

A medicinal chemist's guide to molecular interactions

1 reference

12 December 2020

Features and development of Coot

1 reference

12 December 2020

Isatin, regional distribution in rat brain and tissues.

1 reference

12 December 2020

Probing the probes: fitness factors for small molecule tools

1 reference

12 December 2020

The role of cysteine oxidation in DJ-1 function and dysfunction

1 reference

12 December 2020

Selective inhibition of BET bromodomains

1 reference

12 December 2020

Protein thermal shifts to identify low molecular weight fragments

1 reference

12 December 2020

Hsp31 of Escherichia coli K-12 is glyoxalase III.

1 reference

12 December 2020

Neuroprotective effect of a new DJ-1-binding compound against neurodegeneration in Parkinson's disease and stroke model rats

1 reference

12 December 2020

Proteomic analysis identified DJ-1 as a cisplatin resistant marker in non-small cell lung cancer

1 reference

12 December 2020

DJ-1 promotes invasion and metastasis of pancreatic cancer cells by activating SRC/ERK/uPA.

1 reference

12 December 2020

Human DJ-1 and its homologs are novel glyoxalases

1 reference

12 December 2020

DJ-1, a novel biomarker and a selected target gene for overcoming chemoresistance in pancreatic cancer

1 reference

12 December 2020

2'-Benzoyloxycinnamaldehyde-mediated DJ-1 upregulation protects MCF-7 cells from mitochondrial damage.

1 reference

12 December 2020

DJ-1 protects dopaminergic neurons against rotenone-induced apoptosis by enhancing ERK-dependent mitophagy

1 reference

12 December 2020

Incorporation of rapid thermodynamic data in fragment-based drug discovery

1 reference

12 December 2020

The hallmarks of Parkinson's disease

1 reference

12 December 2020

Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity

1 reference

12 December 2020

Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay.

1 reference

12 December 2020

Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases

1 reference

12 December 2020

Thermodynamic and structural characterization of the specific binding of Zn(II) to human protein DJ-1

1 reference

12 December 2020

A Proton Wire and Water Channel Revealed in the Crystal Structure of Isatin Hydrolase

1 reference

12 December 2020

The cellular thermal shift assay for evaluating drug target interactions in cells

1 reference

12 December 2020

Stereospecific mechanism of DJ-1 glyoxalases inferred from their hemithioacetal-containing crystal structures

1 reference

12 December 2020

Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residues

1 reference

12 December 2020

Enzymatic detection and quantification assay of isatin, a putative stress biomarker in blood.

1 reference

12 December 2020

Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureus

1 reference

12 December 2020

Unexpected mitochondrial matrix localization of Parkinson's disease-related DJ-1 mutants but not wild-type DJ-1.

1 reference

12 December 2020

Loss of Glyoxalase 1 Induces Compensatory Mechanism to Achieve Dicarbonyl Detoxification in Mammalian Schwann Cells

1 reference

12 December 2020

DJ-1/PARK7: A New Therapeutic Target for Neurodegenerative Disorders.

1 reference

12 December 2020

Guanine glycation repair by DJ-1/Park7 and its bacterial homologs

1 reference

12 December 2020

Chemical Probe To Monitor the Parkinsonism-Associated Protein DJ-1 in Live Cells

1 reference

12 December 2020

10.1021/ACSCHEMBIO.8B00701

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30063823%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

1 reference