(Q64933175)

English

Proteasome regulation of the chromodomain protein MRG-1 controls the balance between proliferative fate and differentiation in the C. elegans germ line.

scientific article published in January 2015

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scholarly article

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Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6514403

Proteasome regulation of the chromodomain protein MRG-1 controls the balance between proliferative fate and differentiation in the C. elegans germ line. (English)

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Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6514403

Caenorhabditis elegans

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based on heuristic

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author name string

Pratyush Gupta

1

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6514403

Lindsay Leahul

2

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6514403

Xin Wang

3

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6514403

Chris Wang

4

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6514403

Brendan Bakos

5

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6514403

Katie Jasper

6

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6514403

Dave Hansen

7

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6514403

publication date

1 January 2015

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Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6514403

number of pages

12

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based on heuristic

inferred from page(s)

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Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6514403

142

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Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6514403

2

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6514403

291-302

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6514403

Synapsis and chiasma formation in Caenorhabditis elegans require HIM-3, a meiotic chromosome core component that functions in chromosome segregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of transcription through histone H4 acetylation by MOF, an acetyltransferase essential for dosage compensation in Drosophila.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The yeast NuA4 and Drosophila MSL complexes contain homologous subunits important for transcription regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Caenorhabditis elegans cohesion protein with functions in meiotic chromosome pairing and disjunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms underlying ubiquitination

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MRG15 activates the B-myb promoter through formation of a nuclear complex with the retinoblastoma protein and the novel protein PAM14

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the role of RNA amplification in dsRNA-triggered gene silencing

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A conserved RNA-binding protein controls germline stem cells in Caenorhabditis elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Staring, a novel E3 ubiquitin-protein ligase that targets syntaxin 1 for degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MRG-1, a mortality factor-related chromodomain protein, is required maternally for primordial germ cells to initiate mitotic proliferation in C. elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multipotent cell lineages in early mouse development depend on SOX2 function

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic analysis of Caenorhabditis elegans glp-1 mutants suggests receptor interaction or competition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide RNAi screening in Caenorhabditis elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MRGX Is a Novel Transcriptional Regulator That Exhibits Activation or Repression of the B-myb Promoter in a Cell Type-dependent Manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of the proliferation versus meiotic development decision in the C. elegans germline through regulation of GLD-1 protein accumulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eaf3 regulates the global pattern of histone acetylation in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A map of the interactome network of the metazoan C. elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of C. elegans RING finger protein 1, a binding partner of ubiquitin-conjugating enzyme 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multi-pathway control of the proliferation versus meiotic development decision in the Caenorhabditis elegans germline

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GLD-3 and control of the mitosis/meiosis decision in the germline of Caenorhabditis elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translational repression of C. elegans p53 by GLD-1 regulates DNA damage-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MRG15 regulates embryonic development and cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional analysis of MRG-1: the ortholog of human MRG15 in Caenorhabditis elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eaf3 chromodomain interaction with methylated H3-K36 links histone deacetylation to Pol II elongation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide prediction of C. elegans genetic interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-resolution ChIP-chip analysis reveals that the Drosophila MSL complex selectively identifies active genes on the male X chromosome

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MRG-1, an autosome-associated protein, silences X-linked genes and protects germline immortality in Caenorhabditis elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the MORF/MRG family of genes in cell growth, differentiation, DNA repair, and thereby aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spatial regulation of an E3 ubiquitin ligase directs selective synapse elimination

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitin-mediated pathways in C. elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide analysis reveals MOF as a key regulator of dosage compensation and gene expression in Drosophila

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteasomal regulation of the proliferation vs. meiotic entry decision in the Caenorhabditis elegans germ line

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MRG15, a component of HAT and HDAC complexes, is essential for proliferation and differentiation of neural precursor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A "latent niche" mechanism for tumor initiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The emerging complexity of protein ubiquitination

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cell senescence inducing gene product MORF4 is regulated by degradation via the ubiquitin/proteasome pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translational control in the C. elegans hermaphrodite germ line

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple and efficient method for direct cloning of PCR products using ddT-tailed vectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PRP-17 and the pre-mRNA splicing pathway are preferentially required for the proliferation versus meiotic development decision and germline sex determination in Caenorhabditis elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Emerging role of the MORF/MRG gene family in various biological processes, including aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conditional inactivation of MRG15 gene function limits survival during larval and adult stages of Drosophila melanogaster

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MicroRNA gene regulatory pathways in the establishment and maintenance of ESC identity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetic modifications in pluripotent and differentiated cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large scale phosphoproteome profiles comprehensive features of mouse embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MRG15 activates the cdc2 promoter via histone acetylation in human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exploring the link between MORF4L1 and risk of breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of the chromatin regulator MRG15 limits neural stem/progenitor cell proliferation via increased expression of the p21 Cdk inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteomic and phosphoproteomic comparison of human ES and iPS cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The chromodomain protein MRG-1 facilitates SC-independent homologous pairing during meiosis in Caenorhabditis elegans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MRG-1 is required for genomic integrity in Caenorhabditis elegans germ cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TEG-1 CD2BP2 regulates stem cell proliferation and sex determination in the C. elegans germ line and physically interacts with the UAF-1 U2AF65 splicing factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HECT and RING finger families of E3 ubiquitin ligases at a glance

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C. elegans rrf-1 mutations maintain RNAi efficiency in the soma in addition to the germline

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stem cell proliferation versus meiotic fate decision in Caenorhabditis elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PUF-8, a Pumilio homolog, inhibits the proliferative fate in the Caenorhabditis elegans germline

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of pluripotency and cellular reprogramming by the ubiquitin-proteasome system

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

dBre1/dSet1-dependent pathway for histone H3K4 trimethylation has essential roles in controlling germline stem cell maintenance and germ cell differentiation in the Drosophila ovary.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Germline stem cells and their regulation in the nematode Caenorhabditis elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bre1a, a histone H2B ubiquitin ligase, regulates the cell cycle and differentiation of neural precursor cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase CK2 both promotes robust proliferation and inhibits the proliferative fate in the C. elegans germ line.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genetics of Caenorhabditis elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in gld-1, a female germ cell-specific tumor suppressor gene in Caenorhabditis elegans, affect a conserved domain also found in Src-associated protein Sam68

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GLP-1 is localized to the mitotic region of the C. elegans germ line

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the multiple roles of gld-1 in germline development: interactions with the sex determination cascade and the glp-1 signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular characterization of the male-specific lethal-3 gene and investigations of the regulation of dosage compensation in Drosophila

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GLD-1, a cytoplasmic protein essential for oocyte differentiation, shows stage- and sex-specific expression during Caenorhabditis elegans germline development

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic regulation of entry into meiosis in Caenorhabditis elegans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific interference by ingested dsRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25564623

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1242/DEV.115147

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6514403

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6514403

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6514403

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