(Q34143430)

31 July 2017

Epigenetic modifications in pluripotent and differentiated cells (English)

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31 July 2017

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1

Alexander Meissner

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31 July 2017

1 October 2010

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31 July 2017

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31 July 2017

28

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31 July 2017

1079-1088

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31 July 2017

10

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https://scigraph.springernature.com/pub.10.1038/nbt.1684

31 July 2017

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cites work

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Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

21 January 2018

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Strategies and new developments in the generation of patient-specific pluripotent stem cells

21 January 2018

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Epigenetic reprogramming in mammalian development

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Nuclear cloning and epigenetic reprogramming of the genome

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Active demethylation of the paternal genome in the mouse zygote

21 January 2018

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Dynamic reprogramming of DNA methylation in the early mouse embryo.

21 January 2018

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Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line

21 January 2018

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Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse.

21 January 2018

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Stem cells and early lineage development

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Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal

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Promotion of trophoblast stem cell proliferation by FGF4

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Establishment in culture of pluripotential cells from mouse embryos

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Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

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Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines

21 January 2018

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Derivation of Embryonic Stem-Cell Lines from Human Blastocysts

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Embryonic stem cell lines derived from human blastocysts

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Capturing pluripotency

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Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming

21 January 2018

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Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation

21 January 2018

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The epigenomics of cancer

21 January 2018

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EUKARYOTIC CYTOSINE METHYLTRANSFERASES

21 January 2018

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Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells

21 January 2018

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Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2

21 January 2018

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Somatic mutations in the neurofibromatosis 1 gene in human tumors

21 January 2018

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

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Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization.

21 January 2018

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Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting

21 January 2018

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Dnmt3L and the establishment of maternal genomic imprints.

21 January 2018

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Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L

21 January 2018

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Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation

21 January 2018

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DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

21 January 2018

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Resetting the epigenome beyond pluripotency in the germline

21 January 2018

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Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.

21 January 2018

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The language of covalent histone modifications

21 January 2018

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Histone lysine demethylases: emerging roles in development, physiology and disease

21 January 2018

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Mechanisms of transcriptional memory

21 January 2018

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Histones: annotating chromatin

21 January 2018

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21 January 2018

The mammalian epigenome

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Role of histone H3 lysine 27 methylation in Polycomb-group silencing

21 January 2018

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Mechanism of Polycomb group gene silencing.

21 January 2018

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The polycomb-group gene Ezh2 is required for early mouse development

21 January 2018

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Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

21 January 2018

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Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells

21 January 2018

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Positional cloning of a global regulator of anterior-posterior patterning in mice.

21 January 2018

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Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development

21 January 2018

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Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene

21 January 2018

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Histone H3-K9 methyltransferase ESET is essential for early development

21 January 2018

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Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

21 January 2018

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Chromatin modification and epigenetic reprogramming in mammalian development

21 January 2018

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Genetic and epigenetic regulators of pluripotency

21 January 2018

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Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

21 January 2018

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Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells

21 January 2018

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Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells

21 January 2018

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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

21 January 2018

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A bivalent chromatin structure marks key developmental genes in embryonic stem cells

21 January 2018

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Dynamic changes in the human methylome during differentiation

21 January 2018

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Human DNA methylomes at base resolution show widespread epigenomic differences

21 January 2018

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Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors.

21 January 2018

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Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis

21 January 2018

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Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells.

21 January 2018

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Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b

21 January 2018

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Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency

21 January 2018

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Global loss of imprinting leads to widespread tumorigenesis in adult mice

21 January 2018

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Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation

21 January 2018

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Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5.

21 January 2018

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Polycomb complexes repress developmental regulators in murine embryonic stem cells

21 January 2018

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Developmental biology. Pluripotent chromatin state

21 January 2018

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Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

21 January 2018

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The profile of repeat-associated histone lysine methylation states in the mouse epigenome

21 January 2018

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SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state

21 January 2018

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Large-scale structure of genomic methylation patterns

21 January 2018

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Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome

21 January 2018

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Linking DNA methylation and histone modification: patterns and paradigms

21 January 2018

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Dissecting direct reprogramming through integrative genomic analysis

21 January 2018

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Transcriptional repression and DNA hypermethylation of a small set of ES cell marker genes in male germline stem cells

21 January 2018

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Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a.

21 January 2018

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Allele-specific non-CpG methylation of the Nf1 gene during early mouse development

21 January 2018

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De novo methylation of MMLV provirus in embryonic stem cells: CpG versus non-CpG methylation

21 January 2018

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Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning

21 January 2018

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Gardening the genome: DNA methylation in Arabidopsis thaliana

21 January 2018

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Interchromosomal interactions and olfactory receptor choice

21 January 2018

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

21 January 2018

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The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

21 January 2018

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Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

21 January 2018

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A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis

21 January 2018

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Active DNA demethylation: many roads lead to Rome.

21 January 2018

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Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases

21 January 2018

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A chromatin landmark and transcription initiation at most promoters in human cells

21 January 2018

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Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

21 January 2018

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Regulatory networks in embryo-derived pluripotent stem cells

21 January 2018

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Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells.

21 January 2018

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H3K64 trimethylation marks heterochromatin and is dynamically remodeled during developmental reprogramming.

21 January 2018

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Global transcription in pluripotent embryonic stem cells.

21 January 2018

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Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution

21 January 2018

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Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA.

21 January 2018

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Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells

21 January 2018

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De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes

21 January 2018

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G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis.

21 January 2018

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Retroviral expression in embryonic stem cells and hematopoietic stem cells

21 January 2018

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Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET.

21 January 2018

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DNMT1 maintains progenitor function in self-renewing somatic tissue

21 January 2018

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DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.

21 January 2018

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DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells

21 January 2018

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Comprehensive methylome map of lineage commitment from haematopoietic progenitors

21 January 2018

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De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells

21 January 2018

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The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

21 January 2018

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A region of the human HOXD cluster that confers polycomb-group responsiveness

21 January 2018

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Jarid2 and PRC2, partners in regulating gene expression

21 January 2018

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JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

21 January 2018

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Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells

21 January 2018

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Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells

21 January 2018

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Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

21 January 2018

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Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

21 January 2018

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Transcription. Repressive transcription

21 January 2018

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Nuclear reprogramming and pluripotency

21 January 2018

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

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Reprogramming of human somatic cells to pluripotency with defined factors

21 January 2018

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

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Induced pluripotent stem cell lines derived from human somatic cells

21 January 2018

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Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution

21 January 2018

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Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells

21 January 2018

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In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

21 January 2018

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Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

21 January 2018

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A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog

21 January 2018

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Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures

21 January 2018

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Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

21 January 2018

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Epigenetic memory of active gene transcription is inherited through somatic cell nuclear transfer

21 January 2018

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Epigenetic memory of an active gene state depends on histone H3.3 incorporation into chromatin in the absence of transcription

21 January 2018

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Cloned mice have an obese phenotype not transmitted to their offspring

21 January 2018

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Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.

21 January 2018

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Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus

21 January 2018

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Initial sequencing and analysis of the human genome

21 January 2018

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Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells

21 January 2018

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Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

21 January 2018

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Demethylation of the zygotic paternal genome

21 January 2018

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The quantitative separation of purines, pyrimidines, and nucleosides by paper chromatography.

21 January 2018

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12 December 2020

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency

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12 December 2020

The Polycomb-group gene eed is required for normal morphogenetic movements during gastrulation in the mouse embryo.

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12 December 2020

KMT1E mediated H3K9 methylation is required for the maintenance of embryonic stem cells by repressing trophectoderm differentiation

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12 December 2020

Mitochondria and the death of oocytes

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12 December 2020

Distinctive chromatin in human sperm packages genes for embryo development

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12 December 2020

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

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12 December 2020

Genome-scale DNA methylation maps of pluripotent and differentiated cells

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12 December 2020

Identifiers

DOI

10.1038/NBT.1684

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31 July 2017

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PubMed ID

20944600