(Q64944024)

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28 April 2020

title

Histone deacetylase 4 promotes type I interferon signaling, restricts DNA viruses, and is degraded via vaccinia virus protein C6 (English)

1 reference

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28 April 2020

vaccinia virus

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7

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28 April 2020

Geoffrey Lilley Smith

9

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28 April 2020

Yongxu Lu

1

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28 April 2020

Andrei I Smid

6

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28 April 2020

author name string

Jennifer H Stuart

2

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28 April 2020

Callum Talbot-Cooper

3

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28 April 2020

Shuchi Agrawal-Singh

4

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28 April 2020

Brian Huntly

5

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28 April 2020

Liane Dupont

8

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28 April 2020

publication date

24 May 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31127039%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

28 April 2020

published in

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28 April 2020

volume

116

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28 April 2020

issue

24

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28 April 2020

page(s)

11997-12006

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Creative Commons Attribution 4.0 International

28 April 2020

copyright license

start time

24 May 2019

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Vaccinia virus gene A36R encodes a M(r) 43-50 K protein on the surface of extracellular enveloped virus

1 reference

12 December 2020

HDAC4 deacetylase associates with and represses the MEF2 transcription factor

1 reference

12 December 2020

Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization

1 reference

12 December 2020

Regulation of histone deacetylase 4 by binding of 14-3-3 proteins

1 reference

12 December 2020

Human telomerase reverse transcriptase-immortalized MRC-5 and HCA2 human fibroblasts are fully permissive for human cytomegalovirus

1 reference

12 December 2020

Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9.

1 reference

12 December 2020

Histone deacetylase 4 possesses intrinsic nuclear import and export signals

1 reference

12 December 2020

Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR

1 reference

12 December 2020

MEF2-mediated recruitment of class II HDAC at the EBV immediate early gene BZLF1 links latency and chromatin remodeling

1 reference

12 December 2020

Expression of herpes simplex virus ICP0 inhibits the induction of interferon-stimulated genes by viral infection

1 reference

12 December 2020

The immediate-early protein, ICP0, is essential for the resistance of herpes simplex virus to interferon-alpha/beta

1 reference

12 December 2020

Histone acetylation-mediated regulation of genes in leukaemic cells.

1 reference

12 December 2020

Vaccinia virus cores are transported on microtubules

1 reference

12 December 2020

Interferon-stimulated transcription and innate antiviral immunity require deacetylase activity and histone deacetylase 1.

1 reference

12 December 2020

Requirement of histone deacetylase activity for signaling by STAT1.

1 reference

12 December 2020

Trichostatin A-like hydroxamate histone deacetylase inhibitors as therapeutic agents: toxicological point of view

1 reference

12 December 2020

Histone deacetylase activity is required to recruit RNA polymerase II to the promoters of selected interferon-stimulated early response genes

1 reference

12 December 2020

Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1

1 reference

12 December 2020

Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity.

1 reference

12 December 2020

Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis

1 reference

12 December 2020

Human cytomegalovirus immediate-early 1 protein facilitates viral replication by antagonizing histone deacetylation

1 reference

12 December 2020

Components of the REST/CoREST/histone deacetylase repressor complex are disrupted, modified, and translocated in HSV-1-infected cells

1 reference

12 December 2020

Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications

1 reference

12 December 2020

Positive and negative regulation of the innate antiviral response and beta interferon gene expression by deacetylation

1 reference

12 December 2020

PML contributes to a cellular mechanism of repression of herpes simplex virus type 1 infection that is inactivated by ICP0

1 reference

12 December 2020

Autorepression of the human cytomegalovirus major immediate-early promoter/enhancer at late times of infection is mediated by the recruitment of chromatin remodeling enzymes by IE86

1 reference

12 December 2020

Epstein-Barr nuclear antigen leader protein coactivates transcription through interaction with histone deacetylase 4.

1 reference

12 December 2020

Role for herpes simplex virus 1 ICP27 in the inhibition of type I interferon signaling

1 reference

12 December 2020

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

1 reference

12 December 2020

Lysine acetylation targets protein complexes and co-regulates major cellular functions

1 reference

12 December 2020

Regulation of ICP0-null mutant herpes simplex virus type 1 infection by ND10 components ATRX and hDaxx

1 reference

12 December 2020

Trichostatin A blocks type I interferon production by activated plasmacytoid dendritic cells

1 reference

12 December 2020

Epigenetic regulation of CD8(+) T-lymphocyte mediated suppression of HIV-1 replication

1 reference

12 December 2020

Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7

1 reference

12 December 2020

PKC alpha regulates Sendai virus-mediated interferon induction through HDAC6 and β-catenin

1 reference

12 December 2020

Histone deacetylase inhibitors are potent inducers of gene expression in latent EBV and sensitize lymphoma cells to nucleoside antiviral agents

1 reference

12 December 2020

Recruitment of histone deacetylase 3 to the interferon-A gene promoters attenuates interferon expression

1 reference

12 December 2020

Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages

1 reference

12 December 2020

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

1 reference

12 December 2020

Endocytic tubules regulated by Rab GTPases 5 and 11 are used for envelopment of herpes simplex virus

1 reference

12 December 2020

The replication defect of ICP0-null mutant herpes simplex virus 1 can be largely complemented by the combined activities of human cytomegalovirus proteins IE1 and pp71

1 reference

12 December 2020

Histone deacetylase (HDAC) inhibitors with a novel connecting unit linker region reveal a selectivity profile for HDAC4 and HDAC5 with improved activity against chemoresistant cancer cells.

1 reference

12 December 2020

Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity

1 reference

12 December 2020

Genome engineering using the CRISPR-Cas9 system

1 reference

12 December 2020

Histone deacetylase classes I and II regulate Kaposi's sarcoma-associated herpesvirus reactivation

1 reference

12 December 2020

Primary macrophages rely on histone deacetylase 1 and 2 expression to induce type I interferon in response to gammaherpesvirus infection

1 reference

12 December 2020

Regulation of type I interferon responses

1 reference

12 December 2020

HSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase, and cell derivation

1 reference

12 December 2020

Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

1 reference

12 December 2020

Analysis of the functional interchange between the IE1 and pp71 proteins of human cytomegalovirus and ICP0 of herpes simplex virus 1.

1 reference

12 December 2020

Type I interferons in infectious disease

1 reference

12 December 2020

Inhibition of class I histone deacetylases by romidepsin potently induces Epstein-Barr virus lytic cycle and mediates enhanced cell death with ganciclovir

1 reference

12 December 2020

HDAC6 regulates cellular viral RNA sensing by deacetylation of RIG-I.

1 reference

12 December 2020

Hypothalamic leptin action is mediated by histone deacetylase 5.

1 reference

12 December 2020

HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expression

1 reference

12 December 2020

Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity

1 reference

12 December 2020

Rb selectively inhibits innate IFN-β production by enhancing deacetylation of IFN-β promoter through HDAC1 and HDAC8.

1 reference

12 December 2020

Vaccinia Virus Protein C6 Inhibits Type I IFN Signalling in the Nucleus and Binds to the Transactivation Domain of STAT2

1 reference

12 December 2020

How Does Vaccinia Virus Interfere With Interferon?

1 reference

12 December 2020

Innate responses to gene knockouts impact overlapping gene networks and vary with respect to resistance to viral infection

1 reference

12 December 2020

Host HDAC4 Regulates the Antiviral Response by Inhibiting the Phosphorylation of IRF3.

1 reference

12 December 2020

ATXN3 Positively Regulates Type I IFN Antiviral Response by Deubiquitinating and Stabilizing HDAC3

1 reference

12 December 2020

Histone H2A.Z Suppression of Interferon-Stimulated Transcription and Antiviral Immunity Is Modulated by GCN5 and BRD2

1 reference

12 December 2020

HDAC stimulates gene expression through BRD4 availability in response to IFN and in interferonopathies

1 reference

12 December 2020

PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells

1 reference

12 December 2020

HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1816399116

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31127039%20AND%20SRC:MED&resulttype=core&format=json

28 April 2020

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28 April 2020

PubMed publication ID

31127039

1 reference