(Q68037596)

English

Evaluation of inhibitory guanine nucleotide regulatory protein Gi function in hepatocyte and liver membranes from obese Zucker (fa/fa) rats and their lean (Fa/?) littermates

scientific article published on 01 August 1991

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1936659%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

Evaluation of inhibitory guanine nucleotide regulatory protein Gi function in hepatocyte and liver membranes from obese Zucker (fa/fa) rats and their lean (Fa/?) littermates (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1936659%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

author name string

P Young

1

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Europe PubMed Central

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20 September 2019

D M Kirkham

2

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Europe PubMed Central

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20 September 2019

G J Murphy

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1936659%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

M A Cawthorne

4

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20 September 2019

publication date

1 August 1991

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20 September 2019

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1936659%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

34

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20 September 2019

8

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1936659%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

565-569

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1936659%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

Multiple defects occur in the guanine nucleotide regulatory protein system in liver plasma membranes of obese (fa/fa) but not lean (Fa/Fa) Zucker rats: loss of functional Gi and abnormal Gs function

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apparent loss of Gi protein activity in the diabetic retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The regulation of adenylate cyclase in liver membranes of lean and obese mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of the inhibitory effect of guanine nucleotides on adenylate cyclase activity in white adipocyte membranes of the ob/ob mouse. Effect of the ob gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P2-purinergic receptors are coupled to two signal transduction systems leading to inhibition of cAMP generation and to production of inositol trisphosphate in rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of tryptophan on glucose synthesis in rats and guinea pigs

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of islet activating protein on oral glucose tolerance in the genetically obese fa/fa rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glucagon receptor of rat liver plasma membrane can couple to adenylate cyclase without activating it.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abolition of the expression of inhibitory guanine nucleotide regulatory protein Gi activity in diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic nucleotides in diabetes mellitus and obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of intact hepatocytes with either the phorbol ester TPA or glucagon elicits the phosphorylation and functional inactivation of the inhibitory guanine nucleotide regulatory protein Gi.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A highly sensitive adenylate cyclase assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conversion of adrenergic mechanism from an alpha- to a beta-type during primary culture of rat hepatocytes. Accompanying decreases in the function of the inhibitory guanine nucleotide regulatory component of adenylate cyclase identified as the subst

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal regulation of cAMP accumulation in pancreatic islets of obese mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Guanine nucleotide binding regulatory proteins and adenylate cyclase in livers of streptozotocin- and BB/Wor-diabetic rats. Immunodetection of Gs and Gi with antisera prepared against synthetic peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Guanosine 5'-(beta, gamma-imido)triphosphate inhibition of forskolin-activated adenylate cyclase is mediated by the putative inhibitory guanine nucleotide regulatory protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of streptozotocin-diabetic rats with metformin restores the ability of insulin to inhibit adenylate cyclase activity and demonstrates that insulin does not exert this action through the inhibitory guanine nucleotide regulatory protein Gi.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1936659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00400274

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1936659%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1936659%20AND%20SRC:MED&resulttype=core&format=json

20 September 2019

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