(Q68236601)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1644796%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

title

Purification and characterization of furin, a Kex2-like processing endoprotease, produced in Chinese hamster ovary cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1644796%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

main subject

proprotein convertases

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1644796

Saccharomyces cerevisiae proteins

20 October 2022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1644796

20 October 2022

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)41971-0

20 October 2022

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)41971-0

20 October 2022

author name string

K. Hatsuzawa

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1644796

20 October 2022

M. Nagahama

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1644796

20 October 2022

S. Takahashi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1644796

20 October 2022

K. Takada

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1644796

20 October 2022

K. Murakami

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1644796

20 October 2022

K. Nakayama

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1644796

20 October 2022

language of work or name

English

0 references

publication date

1 August 1992

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1644796%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

August 1992

0 references

15 August 1992

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1644796

full work available at URL

20 October 2022

http://intl.jbc.org/cgi/content/abstract/267/23/16094

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1644796

https://api.elsevier.com/content/article/PII:S0021925818419710?httpAccept=text/xml

20 October 2022

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)41971-0

https://api.elsevier.com/content/article/PII:S0021925818419710?httpAccept=text/plain

20 October 2022

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)41971-0

Journal of Biological Chemistry

20 October 2022

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1644796%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

volume

267

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1644796%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

page(s)

16094-16099

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1644796%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

issue

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1644796%20AND%20SRC:MED&resulttype=core&format=json

Post-translational proteolysis in polypeptide hormone biosynthesis

23 September 2019

cites work

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20 October 2022

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The tissue-specific processing of Pro-ACTH/Endorphin recent advances and unsolved problems

20 October 2022

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Proteolysis in Neuropeptide Processing and Other Neural Functions

20 October 2022

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Endopeptidases and prohormone processing

20 October 2022

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The molecular basis of blood coagulation

20 October 2022

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The molecular biology of influenza virus pathogenicity

20 October 2022

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Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor

20 October 2022

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Yeast KEX2 genes encodes an endopeptidase homologous to subtilisin-like serine proteases

20 October 2022

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Characterization of KEX2-encoded endopeptidase from yeast Saccharomyces cerevisiae

20 October 2022

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Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine protease

20 October 2022

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Structural and enzymatic characterization of a purified prohormone-processing enzyme: secreted, soluble Kex2 protease

20 October 2022

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Yeast KEX2 endopeptidase correctly cleaves a neuroendocrine prohormone in mammalian cells

20 October 2022

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The yeast KEX-2-processing endoprotease is active in the Golgi apparatus of transfected NIH 3T3 fibroblasts

20 October 2022

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Intracellular targeting and structural conservation of a prohormone-processing endoprotease.

20 October 2022

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Structural homology between the human fur gene product and the subtilisin-like protease encoded by yeast KEX2

20 October 2022

17

1 reference

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Sequence of the cDNA encoding rat furin, a possible propeptide-processing endoprotease

20 October 2022

18

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)41971-0

Structure and expression of mouse furin, a yeast Kex2-related protease. Lack of processing of coexpressed prorenin in GH4C1 cells

20 October 2022

19

1 reference

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cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases

20 October 2022

21

1 reference

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Isolation of two complementary deoxyribonucleic acid clones from a rat insulinoma cell line based on similarities to Kex2 and furin sequences and the specific localization of each transcript to endocrine and neuroendocrine tissues in rats

20 October 2022

22

1 reference

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Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans

20 October 2022

23

1 reference

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Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.

20 October 2022

24

1 reference

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Cloning and Functional Expression of a Novel Endoprotease Involved in Prohormone Processing at Dibasic Sites1

20 October 2022

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Isolation and functional expression of a mammalian prohormone processing enzyme, murine prohormone convertase 1.

20 October 2022

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Identification of a Second Human Subtilisin-Like Protease Gene in thefes/fpsRegion of Chromosome 15

20 October 2022

28

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Prohormone processing in Xenopus oocytes: characterization of cleavage signals and cleavage enzymes

20 October 2022

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cDNA sequence of a Drosophila melanogaster gene, Dfur1, encoding a protein structurally related to the subtilisin-like proprotein processing enzyme furin

20 October 2022

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PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues

20 October 2022

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Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes

20 October 2022

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Identification of a somatostatin-14-generating propeptide converting enzyme as a member of the kex2/furin/PC family

20 October 2022

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Furin is a subtilisin-like proprotein processing enzyme in higher eukaryotes

20 October 2022

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Expression of a human proprotein processing enzyme: correct cleavage of the von Willebrand factor precursor at a paired basic amino acid site

20 October 2022

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Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo

20 October 2022

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1 reference

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Functional expression of furin demonstrating its intracellular localization and endoprotease activity for processing of proalbumin and complement pro-C3.

20 October 2022

37

1 reference

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Sequence requirements for proteolytic cleavage of precursors with paired basic amino acids

20 October 2022

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Evidence that differentiates between precursor cleavages at dibasic and Arg-X-Lys/Arg-Arg sites

20 October 2022

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1 reference

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fur gene expression as a discriminating marker for small cell and nonsmall cell lung carcinomas

20 October 2022

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Molecular and enzymatic properties of furin, a Kex2-like endoprotease involved in precursor cleavage at Arg-X-Lys/Arg-Arg sites.

20 October 2022

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Purification of mouse Ren 2 prorenin produced in Chinese hamster ovary cells.

20 October 2022

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A membrane-bound, calcium-dependent protease in yeast alpha-cell cleaving on the carboxyl side of paired basic residues

20 October 2022

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

20 October 2022

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Sequence requirements for prohormone processing in mouse pituitary AtT-20 cells. Analysis using prorenins as model substrates

20 October 2022

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Expression of the Saccharomyces cerevisiae Kex2p endoprotease in inset cells. Evidence for a carboxy-terminal autoprocessing event

20 October 2022

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Sorting within the regulated secretory pathway occurs in the trans-Golgi network

20 October 2022

50

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Conversion of proinsulin to insulin occurs coordinately with acidification of maturing secretory vesicles

20 October 2022

51

1 reference

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Proteolytic maturation of insulin is a post-Golgi event which occurs in acidifying clathrin-coated secretory vesicles

20 October 2022

52

1 reference

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Active-site geometry of proteinase K. Crystallographic study of its complex with a dipeptide chloromethyl ketone inhibitor

20 October 2022

53

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)41971-0

Characterization of PC2, a mammalian Kex2 homologue, following expression of the cDNA in microinjected Xenopus oocytes

20 October 2022

54

1 reference

https://api.crossref.org/works/10.1016/S0021-9258(18)41971-0

20 October 2022

Identifiers

0 references

1 reference