(Q68631795)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2258421%20AND%20SRC:MED&resulttype=core&format=json

26 September 2019

review article

1 reference

title

Analysis of drugs and other toxic substances in biological samples for pharmacokinetic studies (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2258421%20AND%20SRC:MED&resulttype=core&format=json

26 September 2019

author name string

G W Peng

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2258421%20AND%20SRC:MED&resulttype=core&format=json

26 September 2019

W L Chiou

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2258421%20AND%20SRC:MED&resulttype=core&format=json

26 September 2019

publication date

1 October 1990

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2258421%20AND%20SRC:MED&resulttype=core&format=json

26 September 2019

volume

531

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2258421%20AND%20SRC:MED&resulttype=core&format=json

26 September 2019

page(s)

3-50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2258421%20AND%20SRC:MED&resulttype=core&format=json

Rational therapeutic drug monitoring

26 September 2019

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Critical evaluation of the potential error in pharmacokinetic studies of using the linear trapezoidal rule method for the calculation of the area under the plasma level--time curve

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7 January 2021

Procainamide Dosage Schedules, Plasma Concentrations, and Clinical Effects

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Cimetidine-procainamide pharmacokinetic interaction in man: Evidence of competition for tubular secretion of basic drugs

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Pharmacokinetic approach to intravenous procainamide therapy

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7 January 2021

Procainamide administration during continuous ambulatory peritoneal dialysis

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7 January 2021

Procainamide pharmacokinetics in patients with acute myocardial infarction or congestive heart failure

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7 January 2021

Population pharmacokinetics of procainamide from routine clinical data

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7 January 2021

Antiarrhythmic efficacy, pharmacokinetics and safety of N-acetylprocainamide in human subjects: Comparison with procainamide

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7 January 2021

Pharmacokinetics in man of theN-acetylated metabolite of proeainamide

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7 January 2021

Sample pretreatment in the trace determination of drugs in biological fluids.

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7 January 2021

Drug-protein binding interferences caused by the plasticizer TBEP.

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7 January 2021

Blood collection techniques, heparin and quinidine protein binding

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7 January 2021

Effect of blood sample tubes on amiodarone and desethylamiodarone concentrations

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7 January 2021

Preparation of serum and plasma samples for determination of tricyclic antidepressants: effects of blood collection tubes and storage

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7 January 2021

Effect of Serum Separator Blood Collection Tubes on Drug Concentrations

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7 January 2021

Adsorption of methotrexate onto glassware and syringes

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7 January 2021

Quantitative analysis of tricyclic antidepressants in serum from psychiatric patients

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7 January 2021

Relevancy of tricyclic antidepressant plasma levels

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7 January 2021

Analysis and evaluation of zinc and copper in human plasma and serum.

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7 January 2021

Effect of heparin and storage on human plasma free fatty acid concentration

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7 January 2021

Determination of Pyridostigmine in Mammalian Plasma: Addressing Current Problems

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Rapid and sensitive high-performance liquid chromatographic assay for metformin in plasma and urine using ion-pair extraction techniques

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7 January 2021

Sensitive high-performance liquid chromatographic assay for determination of amiloride in biologic fluids using an ion-pair extraction method.

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7 January 2021

Determination of amiodarone and its metabolite N-desethylamiodarone in serum by high-performance liquid chromatography--comparison of different extraction procedures

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7 January 2021

Solid-phase extraction and high-performance liquid chromatographic method for chlorpromazine and thirteen metabolites

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7 January 2021

Column liquid chromatographic determination of hydrolysed bopindolol, in the picogram per millilitre range in plasma, using cartridge extraction and dual electrochemical detection

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7 January 2021

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7 January 2021

Determination of sub-nanogram amounts of dihydroergotamine in plasma and urine using liquid chromatography and fluorimetric detection with off-line and on-line solid-phase drug enrichment

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7 January 2021

Direct determination of dextromethorphan and its three metabolites in urine by high-performance liquid chromatography using a precolumn switching system for sample clean-up

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7 January 2021

Effect of sample preparation and liquid chromatography column choice on selectivity and precision of plasma catecholamine determination

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7 January 2021

High-performance liquid chromatographic assay for urinary metabolises of a drug after extraction by antiserum to the drug: An example using erythro-9-(2-hydroxy-3-nonyl) hypoxanthine

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7 January 2021

Antibody-mediated extraction/negative-ion chemical ionization mass spectrometric measurement of thromboxane B 2 and 2,3-dinor-thromboxane B 2 in human and rat urine

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7 January 2021

Extraction of thromboxane B2 from urine using an immobilized antibody column for subsequent analysis by gas chromatography-mass spectrometry

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7 January 2021

Determination of chloramphenicol in swine muscle tissue using a monoclonal antibody-mediated clean-up procedure

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7 January 2021

High-performance liquid chromatographic determination of ibuprofen in human plasma and urine by direct injection

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7 January 2021

Quantitative analysis of furosemide in micro plasma volumes by high-performance liquid column chromatography

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7 January 2021

High-performance liquid chromatographic drug analysis by direct injection of whole blood samples. I. Determination of moderately hydrophobic drugs incorporated into blood corpuscles

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7 January 2021

High-performance liquid chromatographic drug analysis by direct injection of whole blood samples. II. Determination of hydrophilic drugs

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7 January 2021

High-performance liquid chromatographic drug analysis by direct injection of whole blood samples. III. Determination of hydrophobic drugs adsorbed on blood cell membranes

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7 January 2021

Shielded hydrophobic phase: a new concept for direct injection analysis of biological fluids by high-performance liquid chromatography

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7 January 2021

A direct injection method of plasma samples onto a reverse phase column for the determination of drugs

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7 January 2021

Direct plasma injection using internal surface reversed-phase high-performance liquid chromatography: feasibility study using propofol as a model compound

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7 January 2021

Rapid analysis of peptide toxins in cyanobacteria

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7 January 2021

High-performance liquid chromatographic determination of 2',3'-dideoxycytidine and 3'-azido-3'-deoxythymidine in plasma using a column-switching technique

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7 January 2021

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7 January 2021

A new approach for dealing with the stability of drugs in biological fluids

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7 January 2021

Formation of artifactual metabolites of doxylamine following acid hydrolysis

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7 January 2021

Pharmacokinetics of drugs in blood III: Metabolism of procainamide and storage effect of blood samples

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7 January 2021

Erythrocytes as barriers for drug elimination in the isolated rat liver. I. Doxorubicin

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7 January 2021

Sample handling techniques when analyzing regulatory peptides.

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7 January 2021

Factors affecting the stability and separation of biogenic amines and their metabolites. Simultaneous measurement by HPLC with electrochemical detection

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7 January 2021

Degradation of clonazepam in serum by light confirmed by means of a high performance liquid chromatographic method

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7 January 2021

Determination of chloramphenicol in tissues--problems with in vitro metabolism.

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7 January 2021

Biotransformation of nitrosobenzene in the red cell and the role of glutathione

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7 January 2021

Reaction of arylnitroso compounds with mercaptans

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7 January 2021

Metabolic interconversions between imipramine, its N-oxide, and its desmethyl derivative in rat tissues in vitro

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7 January 2021

Negligible excretion of unchanged ketoprofen, naproxen, and probenecid in urine

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7 January 2021

Properties of acyl glucuronides: implications for studies of the pharmacokinetics and metabolism of acidic drugs

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7 January 2021

High-performance liquid chromatographic method for the simultaneous quantitation of diflunisal and its glucuronide and sulfate conjugates in human urine

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7 January 2021

Reactivity considerations in the analysis of glucuronide and sulfate conjugates of diflunisal

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7 January 2021

High-performance liquid chromatographic analysis of diflunisal in plasma and urine: application to pharmacokinetic studies in two normal volunteers

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7 January 2021

Determination of diflunisal in human plasma and urine by fast high-performance liquid chromatography

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7 January 2021

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7 January 2021

Effect of haemolysis on high-performance liquid chromatography measurements of free plasma catecholamines

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7 January 2021

Purity determination and evaluation of new drug substances

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7 January 2021

Inadequate reporting of analytical quality control in the clinical pharmacological literature

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7 January 2021

Bioanalytical aspects on method validation

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7 January 2021

Measuring and maximizing precision in analyses based on use of calibration graphs

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7 January 2021

The Calibration Problem in Statistics and Its Application to Chemistry

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7 January 2021

Comparison of the absolute calibration method with the method of standard addition for the determination of halothane in blood by gas chromatographic headspace analysis

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7 January 2021

Drug Interferences with Plasma Assays in Therapeutic Drug Monitoring

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7 January 2021

Multichannel detection in high-performance liquid chromatography

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7 January 2021

On-line screening for drug metabolites by high-performance liquid chromatography with a diode array UV detector

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7 January 2021

Use of dual-wavelength UV detection in high-performance liquid chromatography for the identification of barbiturates

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7 January 2021

Detection limits and selectivity in electrochemical detectors

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7 January 2021

Evaluation of chromatographic and kit immunoassay techniques for the measurement of theophylline in serum: a study based on external quality assurance measurements

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7 January 2021

External quality assurance of tricyclic antidepressant measurements in serum: eight years of progress?

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7 January 2021

Evaluation of assay techniques for the measurement of antiepileptic drugs in serum: a study based on external quality assurance measurements

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7 January 2021

Comparison of high performance liquid chromatographic and microbiological methods for determination of itraconazole

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7 January 2021

Total and free quinidine by fluorescence polarization immunoassay and comparison with high performance liquid chromatography

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7 January 2021

Correlation of urokinase activity from biopotency and high-performance liquid chromatographic assays

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7 January 2021

Lack of effect of cimetidine on pharmacodynamics and kinetics of single oral doses of R- and S-acenocoumarol

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7 January 2021

Pharmacokinetics of (+)-, (-)- and (+/-)-verapamil after intravenous administration

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7 January 2021

The pharmacokinetics of R- and S-tocainide in patients with acute ventricular arrhythmias

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7 January 2021

Pharmacokinetics of warfarin enantiomers: A search for intrasubject correlations

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7 January 2021

Direct enantiomeric resolution of disopyramide and its metabolite using chiral high-performance liquid chromatography. Application to stereoselective metabolism and pharmacokinetics of racemic disopyramide in man

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7 January 2021

Determination of propranolol enantiomers in human plasma and urine and in rat tissues using chiral stationary-phase liquid chromatography

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7 January 2021

Effects of d,l-verapamil on atrioventricular conduction in relation to its stereoselective first-pass metabolism

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7 January 2021

Stereoselective first-pass metabolism of highly cleared drugs: studies of the bioavailability of L- and D-verapamil examined with a stable isotope technique

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7 January 2021

Analysis of salbutamol enantiomers in human urine by chiral high-performance liquid chromatography and preliminary studies related to the stereoselective disposition kinetics in man

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7 January 2021

Determination of the enantiomeric composition of ibuprofen in human plasma by high-performance liquid chromatography

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7 January 2021

Enantioselective Analysis of Chloroquine and Desethylchloroquine after Oral Administration of Racemic Chloroquine

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7 January 2021

Serum tocainide enantiomer concentrations in human subjects

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7 January 2021

Plasma Protein Binding and Urinary Excretion of R- and S-Epimers of an Arylmalonylamino 1-Oxacephem I: In Humans

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7 January 2021

Species-dependent stereospecific serum protein binding of the oral anticoagulant drug phenprocoumon

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7 January 2021

Protein binding of warfarin enantiomers in serum of humans and rats

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7 January 2021

Indacrinone: natriuretic and uricosuric effects of various ratios of its enantiomers in healthy men.

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7 January 2021

Pharmacology of ketamine isomers in surgical patients.

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7 January 2021

Comparative pharmacology of the ketamine isomers. Studies in volunteers

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7 January 2021

Analgesic and other effects of the d- and l-isomers of penzocine

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7 January 2021

Respiratory and subjective effects of dand l-pentazocine.

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7 January 2021

Haemodynamic effects of the optical isomers of beta-receptor blocking agents

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

A comparison of the cardiovascular effects of (+)-sotalol and (+/-)-sotalol following intravenous administration in normal volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Intracardiac contrast echoes during transvenous His bundle ablation

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Tetramisole in the treatment of nematode infections in man.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

The effect of dextro-, levo-, and racemic verapamil on atrioventricular conduction in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

High-performance liquid chromatographic method for the analysis of debrisoquine and its S-(+)- and R-(-)-hydroxy metabolites in urine

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Pharmacodynamic and pharmacokinetic differences between drug enantiomers in humans: an overview

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Stereochemistry, a basis for sophisticated nonsense in pharmacokinetics and clinical pharmacology

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Importance of drug enantiomers in clinical pharmacology

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Enantiomeric resolution of drug compounds by liquid chromatography

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Separation of amino acid enentiomers by adding a chiral complex to the eluent

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

S-(+)-Flunoxaprofen chloride as chiral fluorescent reagent

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

High-performance liquid chromatographic resolution of the enantiomers of thioridazine, its metabolites and related compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Determination of the S(+)- and R(-)-enantiomers of baclofen in plasma and urine by gas chromatography using a chiral fused-silica capillary column and an electron-capture detector

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Determination of D,L-threo-3,4-dihydroxyphenylserine and of the D- and L-enantiomers in human plasma and urine

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

The determination of (R)- and (S)-glutethimide and the corresponding 4-hydroxyglutethimide metabolises in human serum and urine using a Pirkle-type HPLC chiral stationary phase

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Quantification of the enantiomers of ofloxacin in biological fluids by high-performance liquid chromatography

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

High-performance liquid chromatographic assay of flecainide and its enantiomers in serum.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Rapid determination of the enantiomers of metoprolol, oxprenolol and propranolol in urine

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Free drug concentration monitoring in clinical practice. Rationale and current status

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Problems in therapeutic drug monitoring: free drug level monitoring.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Monitoring of free drug levels: determination of free concentration versus free fraction

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Rationale for monitoring free drug levels

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Free drug measurements: methodology and clinical significance

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Effects of drug-protein binding on trace enrichment of drugs in blood plasma on short precolumns

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Determination of highly protein bound drugs in plasma using high-performance liquid chromatography and column switching, exemplified by the retinoids

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

A highly sensitive and specific radioimmunoassay for quantitation of plasma fluphenazine

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Development of a radioimmunoassay procedure for sulforidazine and its comparison with a high-performance liquid chromatographic method

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Development of a radioimmunoassay procedure for mesoridazine and its comparison with a high-performance liquid chromatographic method

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Problems with the immunoassay of digoxin

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Development and comparative evaluation of radioimmunoassay and gas chromatographic/mass spectrometric procedures for determination of leukotriene B4

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Chemiluminescent and bioluminescent immunoassays

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Evaluation of valproic acid fluoroimmunoassay and comparison with a gas liquid chromatographic method

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Evaluation of tricyclic antidepressant plasma levels by an automated enzyme immunoassay (EMIT) in comparison to a high-performance liquid chromatographic method.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

High-performance liquid chromatographic-radioimmunoassay method for the measurement of angiotensin II peptides in human plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Quantitative immunochromatographic analysis: theory and application to theophylline immunoassay

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Immunological-chromatographic analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Radioreceptor assay for benzodiazepines in biological fluids using a new dry and stable receptor preparation

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Development of a sensitive radioreceptor assay for oxyphenonium in plasma and urine

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Simple and reliable radioreceptor assay for beta-adrenoceptor antagonists and active metabolites in native human plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Lyophilised Receptor Preparation for A Radioreceptor Assay for Anticholinergics

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Biotransformation and excretion: metabolite identification: other mass spectrometric methods

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Biotransformation and excretion: quantitative studies

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Pharmacokinetic drug interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Applications to analytic chemistry: an evaluation of stable isotopes in mass spectral drug assays

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Stable-isotope methodology in the bioavailability study of 17 alpha-methyltestosterone using gas chromatography-mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

The application of stable isotopes to studies of drug bioavailability and bioequivalence

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Chemometrics in pharmaceutical analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

1 reference

7 January 2021

Research and development of biosensors. A review

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

New trends on modified electrodes: applications to drug analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Construction of a naproxen ion-selective electrode and its application to pharmaceutical analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

Acetylcholine Receptor-Based Biosensor

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4347%2800%2982279-3

7 January 2021

10.1016/S0378-4347(00)82279-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2258421%20AND%20SRC:MED&resulttype=core&format=json

26 September 2019

1 reference