(Q70997287)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8599863%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

title

High-dose 7-hydromethotrexate: acute toxicity and lethality in a rat model (English)

1 reference

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15 October 2019

8

J Aarbakke

1 reference

15 October 2019

E Smeland

1

1 reference

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15 October 2019

O M Fuskevåg

2

1 reference

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15 October 2019

K Nymann

3

1 reference

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15 October 2019

J S Svendesn

4

1 reference

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15 October 2019

R Olsen

5

1 reference

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15 October 2019

S Lindal

6

1 reference

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15 October 2019

R M Bremnes

7

1 reference

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15 October 2019

publication date

1 January 1996

1 reference

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Cancer Chemotherapy and Pharmacology

15 October 2019

published in

1 reference

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15 October 2019

volume

37

1 reference

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15 October 2019

issue

5

1 reference

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15 October 2019

page(s)

415-422

1 reference

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https://scigraph.springernature.com/pub.10.1007/s002800050406

15 October 2019

exact match

0 references

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21 January 2018

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21 January 2018

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21 January 2018

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Comparative study on the pharmacokinetics of 7-hydroxy-methotrexate after administration of methotrexate in the dose range of 0.5-33.6 g/m2 to children with acute lymphoblastic leukemia

21 January 2018

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High-dose methotrexate for osteosarcoma: toxicity and clinical results

21 January 2018

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Acute Hepatotoxicity after High-Dose Methotrexate Administration to Rats

21 January 2018

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A simple preparation of the methotrexate metabolites 7-hydroxymethotrexate and 4-deoxy-4-amino-N10-methylpteroic acid

21 January 2018

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Synthesis of the 7-hydroxy metabolites of methotrexate and 10-ethyl-10-deazaaminopterin

21 January 2018

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The effects of diltiazem on methotrexate-induced nephrotoxicity

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7-Hydroxy-methotrexate and clinical toxicity following high-dose methotrexate therapy

21 January 2018

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Kinetics of 7-hydroxy-methotrexate after high-dose methotrexate therapy

21 January 2018

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Clinical pharmacodynamics of high-dose methotrexate in acute lymphocytic leukemia. Identification of a relation between concentration and effect

21 January 2018

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High-dose methotrexate treatment and liver function in patients with osteosarcoma

21 January 2018

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Pharmacokinetics of methotrexate (MTX) and 7-hydroxymethotrexate (7-OH-MTX) in rats and evidence for the metabolism of MTX to 7-OH-MTX

21 January 2018

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Synthesis and biologic evaluation of 7-hydroxymethotrexate, 7-methylaminopterin, and 7-methylmethotrexate

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Methods in testing interrelationships between excretion of drugs via urine and bile

21 January 2018

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The effect of high-dose methotrexate on renal tubules as indicated by urinary lysozyme concentration

21 January 2018

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Protection of cells from methotrexate toxicity by 7-hydroxymethotrexate

21 January 2018

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Enhancement of methotrexate nephrotoxicity after cisplatin therapy

21 January 2018

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21 January 2018

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The relative toxicites of methotrexate and aminopterin

21 January 2018

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Electron microscopic analysis of sequential liver biopsy samples from patients with rheumatoid arthritis. Correlation with light microscopic findings

21 January 2018

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21 January 2018

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Metabolism of the diaminoantifolates: biosynthesis and pharmacology of the 7-hydroxyl and polyglutamyl metabolites of methotrexate and related antifolates

21 January 2018

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Enzymatic synthesis of polyglutamate derivatives of 7-hydroxymethotrexate

21 January 2018

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Biliary elimination of low-dose methotrexate in humans

21 January 2018

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Renal impairment following the combined use of high-dose methotrexate and procarbazine

21 January 2018

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Resistance of the rabbit to methotrexate: Isolation of a drug metabolite with decreased cytotoxicity

21 January 2018

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The safety of administration of massive doses of methotrexate (50 g) with equimolar citrovorum factor rescue in adult patients

21 January 2018

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Removal of methotrexate, leucovorin, and their metabolites by combined hemodialysis and hemoperfusion

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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12 December 2020

Incidence of drug-related deaths secondary to high-dose methotrexate and citrovorum factor administration

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12 December 2020

Prolongation of rat cardiac allograft survival by donor pretreatment. Screening of antineoplastic drugs

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12 December 2020

Synthesis and properties of 7-hydroxymethotrexate polyglutamyl derivatives in Ehrlich ascites tumor cells in vitro

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12 December 2020

Interactions between 7-hydroxymethotrexate and methotrexate at the cellular level in the Ehrlich ascites tumor in vitro

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12 December 2020

Metabolism of methotrexate in man after high and conventional doses

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12 December 2020

Evidence for the facilitated transport of methotrexate polyglutamates into lysosomes derived from S180 cells. Basic properties and specificity for polyglutamate chain length

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12 December 2020

Dose-dependent pharmacokinetics of methotrexate and 7-hydroxymethotrexate in the rat in vivo

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12 December 2020

Dose-dependent metabolism of methotrexate in man and rhesus monkeys

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12 December 2020

Ultrastructural examinations of rat myocardium on low-magnesium diet during administration of methotrexate

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12 December 2020

Formation and elimination of 7-hydroxymethotrexate in the rat in vivo after methotrexate administration

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12 December 2020

Facilitated transport of methotrexate polyglutamates into lysosomes derived from S180 cells. Further characterization and evidence for a simple mobile carrier system with broad specificity for homo- or heteropeptides bearing a C-terminal glutamyl mo

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12 December 2020

Low-dose versus high-dose methotrexate during remission induction in childhood acute lymphoblastic leukemia (Protocol 81-01 update)

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1007/S002800050406

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8599863%20AND%20SRC:MED&resulttype=core&format=json

15 October 2019

1 reference