(Q71324315)

English

Inter- and intra-subject variation in the first-pass elimination of highly cleared drugs during chronic dosing. Studies with deuterated verapamil

scientific article published on 01 January 1984

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6714292%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

Inter- and intra-subject variation in the first-pass elimination of highly cleared drugs during chronic dosing. Studies with deuterated verapamil (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6714292%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

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M Eichelbaum

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6714292%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

A Somogyi

2

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Europe PubMed Central

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17 October 2019

publication date

1 January 1984

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6714292%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

European Journal of Clinical Pharmacology

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6714292%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

26

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6714292%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6714292%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

47-53

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6714292%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

https://scigraph.springernature.com/pub.10.1007/bf00546708

0 references

Drug use in the elderly: a review of problems and special considerations

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of the bioavailability of propranolol and metoprolol by food

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of bioavailability for drugs with a high first-pass effect using oral clearance data

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variability of beta-blocker pharmacokinetics in young volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of the route of administration on the area under the plasma concentration-time curve

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous determination of verapamil and its seven metabolites by high-performance liquid chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug pharmacokinetics in cardiac and hepatic disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological disposition of verapamil in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Verapamil kinetics in normal subjects and patients with coronary artery spasm

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolongation of verapamil elimination kinetics during chronic oral administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Verapamil in cardiology

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of route of administration on drug availability

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of nortriptyline in man after single and multiple oral doses: The predictability of steady-state plasma concentrations from single-dose plasma-level data

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superiority of stable isotope techniques in the assessment of the bioavailability of drugs undergoing extensive first pass elimination. Studies of the relative bioavailability of verapamil tablets

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Individual Differences in the Disposition of Drugs Metabolised in the Body

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of verapamil in human plasma by mass fragmentography using stable isotope-labelled verapamil as internal standard

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydralazine kinetics after single and repeated oral doses

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraindividual variation in drug disposition

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of meso-caval shunt surgery on verapamil kinetics, bioavailability and response

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-performance liquid chromatographic analysis of verapamil. II. Simultaneous quantitation of verapamil and its active metabolite, norverapamil

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological and pharmacological variability in estimated hepatic blood flow in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous determination of the intravenous and oral pharmacokinetic parameters of D,L-verapamil using stable isotope-labelled verapamil.

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Commentary: a physiological approach to hepatic drug clearance

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct measurement of propranolol bioavailability during accumulation to steady-state

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of verapamil on P-R-intervals in relation to verapamil plasma levels following single i.v. and oral administration and during chronic treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics, bioavailability and ECG response of verapamil in patients with liver cirrhosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of hypertrophic obstructive cardiomyopathy with verapamil, a calcium antagonist (author's transl)

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolism of DL-[14C]verapamil in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of Drug Disposition: Hemodynamic Considerations

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Verapamil therapy: a new approach to the pharmacologic treatment of hypertrophic cardiomyopathy. I. Hemodynamic effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct determination of hepatic extraction of verapamil in cardiac patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lorcainide; I. Saturable presystemic elimination

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Verapamil: a review of its pharmacological properties and therapeutic use.

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced verapamil clearance during long-term oral administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/6714292

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00546708

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6714292%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6714292%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

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