(Q39720658)

14 September 2017

1 reference

title

Individual differences in the disposition of drugs metabolised in the body (English)

1 reference

14 September 2017

Individual Differences in the Disposition of Drugs Metabolised in the Body (English)

1 reference

10.2165/00003088-197803020-00005

Crossref

DOI

https://api.crossref.org/works/10.2165/00003088-197803020-00005

3 April 2023

main subject

metabolic inactivation

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A346288

3 April 2023

1 reference

10.2165/00003088-197803020-00005

https://api.crossref.org/works/10.2165/00003088-197803020-00005

3 April 2023

author name string

G. Alvan

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A346288

3 April 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=346288

3 April 2023

publication date

1 March 1978

1 reference

Clinical Pharmacokinetics

14 September 2017

1 reference

14 September 2017

3

1 reference

14 September 2017

155-175

1 reference

14 September 2017

2

1 reference

https://scigraph.springernature.com/pub.10.2165/00003088-197803020-00005

14 September 2017

0 references

cites work

Clearance and biologic half-life as indices of intrinsic hepatic metabolism

1 reference

12 December 2020

Pharmacokinetics of fluoride in man after single and multiple oral doses

1 reference

12 December 2020

Enhancement of the bioavailability of propranolol and metoprolol by food

1 reference

12 December 2020

Biliary excretion and enterochepatic recycling of proscillaridin A after oral adminstration to man

1 reference

12 December 2020

The Absorption of Orally Administered [12α-3H]Digoxin in Man

1 reference

12 December 2020

Enterohepatic circulation of indomethacin and its role in intestinal irritation

1 reference

12 December 2020

Fate of Orally Administered 3 H-Digitoxin in Man with Special Reference to the Absorption

1 reference

12 December 2020

Abnormal pharmacokinetics of phenytoin in a patient with uraemia

1 reference

12 December 2020

Pharmacokinetics of theophylline. Application to adjustment of the clinical dose of aminophylline.

1 reference

12 December 2020

Tricyclic antidepressants. Prolonged plasma levels after overdose

1 reference

12 December 2020

Influence of the route of administration on the area under the plasma concentration-time curve

1 reference

12 December 2020

Metabolic fate of radioactive digitoxin in human subjects

1 reference

12 December 2020

Perfusion-limited of plasma drug binding on hepatic drug extraction

1 reference

12 December 2020

Protein binding of diphenylhydantoin and desmethylimipramine in plasma from patients with poor renal function.

1 reference

12 December 2020

Pharmacokinetics of drugs in patients with the nephrotic syndrome

1 reference

12 December 2020

First pass conjugation and enterohepatic recycling of oxazepam in dogs; intravenous tolerance of oxazepam in propylene glycol

1 reference

12 December 2020

Importance of "first-pass elimination" for interindividual differences in steady-state concentrations of the adrenergic beta-receptor antagonist alprenolol

1 reference

12 December 2020

Clinical and electroencephalographic correlations with serum levels of diphenylhydanotin

1 reference

12 December 2020

Renal Failure, Drug Pharmacokinetics and Drug Action

1 reference

12 December 2020

First pass hydroxylation of nortriptyline: concentrations of parent drug and major metabolites in plasma

1 reference

12 December 2020

Plasma propranolol levels in adults With observations in four children

1 reference

12 December 2020

Serum protein binding as a determinant of warfarin body clearance and anticoagulant effect

1 reference

12 December 2020

Quantitative determination of imipramine and desipramine in human blood plasma by direct densitometry of thin-layer chromatograms

1 reference

12 December 2020

Nonlinear relationship between plasma and red blood cell pharmacokinetics of chlorthalidone in man

1 reference

12 December 2020

Steady-state plasma concentrations of alprenolol in man

1 reference

12 December 2020

Rapidly achieved plasma concentration plateaus, with observations on theophylline kinetics

1 reference

12 December 2020

Explanation of dose-dependent decline of diphenylhydantoin plasma levels by fitting to the integrated form of the Michaelis-Menten equation

1 reference

12 December 2020

Undernutrition and tetracycline half life

1 reference

12 December 2020

Proceedings: "First-pass" effect and dose dependent availability as factors contributing to interindividual differences in equilibrium concentrations of alprenolol in man

1 reference

12 December 2020

Influence of route of administration on drug availability

1 reference

12 December 2020

Enhanced phenacetin metabolism in human subjects fed charcoal-broiled beef

1 reference

12 December 2020

Pharmacokinetics of nortriptyline in man after single and multiple oral doses: The predictability of steady-state plasma concentrations from single-dose plasma-level data

1 reference

12 December 2020

Blood Levels of Drug at the Equilibrium State after Multiple Dosing

1 reference

12 December 2020

The disposition of sulindac

1 reference

12 December 2020

Estimation of population characteristics of pharmacokinetic parameters from routine clinical data

1 reference

12 December 2020

Microsomal enzymes in malnutrition as determined by plasma half life of antipyrine

1 reference

12 December 2020

Diphenylhydantoin elimination kinetics in overdosed children

1 reference

12 December 2020

Individual differences in the pharmacokinetics of monomethylated tricyclic antidepressants: role of genetic and environmental factors and clinical importance

1 reference

12 December 2020

Gas chromatographic assessment of the reproducibility of phenazone plasma half-life in young healthy volunteers

1 reference

12 December 2020

Two-fold interindividual variation in plasma protein binding of phenytoin in patients with epilepsy

1 reference

12 December 2020

Acute intoxication with 5,5-diphenylhydantoin (Dilantin) associated with impairment of biotransformation. Plasma levels and urinary metabolites; and studies in healthy volunteers.

1 reference

12 December 2020

Nonlinear assessment of phenytoin bioavailability

1 reference

12 December 2020

Influence of First-Pass Effect on Availability of Drugs on Oral Administration

1 reference

12 December 2020

Pharmacokinetics of theophylline in children with asthma

1 reference

12 December 2020

Serum-phenytoin levels in management of epilepsy

1 reference

12 December 2020

Plasma protein binding of diphenylhydantoin in man. Interaction with other drugs and the effect of temperature and plasma dilution

1 reference

12 December 2020

Failure of Vitamin C to Affect the Pharmacokinetic Profile of Antipyrine in Man

1 reference

12 December 2020

Commentary: a physiological approach to hepatic drug clearance

1 reference

12 December 2020

Transport and Binding of Methotrexate In Vivo

1 reference

12 December 2020

System for clinical pharmacokinetic monitoring of theophylline therapy

1 reference

12 December 2020

The disposition of propranolol. 3. Decreased half-life and volume of distribution as a result of plasma binding in man, monkey, dog and rat

1 reference

12 December 2020

Prediction of steady-state plasma levels of nortriptyline from single oral dose kinetics: a study in twins.

1 reference

12 December 2020

Effect of environmental factors on drug metabolism: Decreased plasma half-life of antipyrine in workers exposed to chlorinated hydrocarbon insecticides

1 reference

12 December 2020

Pharmacokinetics of oxazepam in healthy volunteers

1 reference

12 December 2020

Pharmacokinetics of intravenous theophylline

1 reference

12 December 2020

Genetic control of isoniazid metabolism in man

1 reference

12 December 2020

Plasma Levels of Imipramine and Desmethylimipramine during Therapy

1 reference

12 December 2020

Amoxycillin: A review of its antibacterial and pharmacokinietic properties and therapeutic use

1 reference

12 December 2020

Clearance concepts in pharmacokinetics

1 reference

12 December 2020

Anticonvulsant effect of diphenylhydantoin relative to plasma levels. A prospective three-year study in ambulant patients with generalized epileptic seizures

1 reference

12 December 2020

Effect of Plasma Protein Binding on Elimination of Warfarin

1 reference

12 December 2020

The effects of age and liver disease on the disposition and elimination of diazepam in adult man

1 reference

12 December 2020

Drug Absorption in Gastrointestinal Disease With Particular Reference to Malabsorption Syndromes

1 reference

12 December 2020

Intrasubject variation in elimination half-lives of drugs which are appreciably metabolized

1 reference

12 December 2020

Pharmacokinetics of Drug Disposition: Hemodynamic Considerations

1 reference

12 December 2020

First-pass metabolism of nortriptyline in man

1 reference

12 December 2020

Biliary elimination of diazepam in man

1 reference

12 December 2020

Prediction of hepatic extraction ratio from in vitro measurement of intrinsic clearance

1 reference

12 December 2020

Biliary excretion of digoxin in man

1 reference

12 December 2020

DIPHENYLHYDANTOIN METABOLISM, BLOOD LEVELS, AND TOXICITY.

1 reference

12 December 2020

Plasma levels of monomethylated tricyclic antidepressants during treatment with imipramine-like compounds

1 reference

12 December 2020

Disposition of propranolol. VI. Independent variation in steady-state circulating drug concentrations and half-life as a result of plasma drug binding in man.

1 reference

12 December 2020

Elimination of antipyrine from saliva as a measure of metabolism in man

1 reference

12 December 2020

Pharmacokinetics of indomethacin

1 reference

12 December 2020

AMPICILLIN LEVELS IN HUMAN BILE

1 reference

12 December 2020

Amobarbital--a probe of hepatic drug oxidation in man

1 reference

12 December 2020

Protein Binding and Kinetics of Drugs in Liver Diseases

1 reference

12 December 2020

Antipyrine metabolism in man: influence of age, alcohol, caffeine, and smoking

1 reference

12 December 2020

Influence of first-pass effect on the systemic availability of propoxyphene.

1 reference

12 December 2020

Effect of pentobarbital on the disposition of alprenolol

1 reference

12 December 2020

Physiological and Pharmacokinetic Complexities in Bioavailability Testing

1 reference

12 December 2020

Kinetics of rifampicin and isoniazid administered alone and in combination to normal subjects and patients with liver disease

1 reference

12 December 2020

The metabolism of fluorides in man

1 reference

12 December 2020

Genetic study of amobarbital elimination based on its kinetics in twins

1 reference

12 December 2020

Elimination of antipyrine and benzo[a]pyrene metabolism in cultured human lymphocytes

1 reference

12 December 2020

Influence of dietary protein and carbohydrate on antipyrine and theophylline metabolism in man

1 reference

12 December 2020

A comparative study of drug metabolism in the isolated perfused liver and in vivo in rats

1 reference

12 December 2020

Disease and Acetylation Polymorphism

1 reference

12 December 2020

Altered Hepatic Blood Flow and Drug Disposition1

1 reference

12 December 2020

Frequency distribution of free warfarin and free phenytoin fraction values in serum of healthy human adults

1 reference

12 December 2020

10.2165/00003088-197803020-00005

Identifiers

DOI

1 reference

Dimensions Publication ID

14 September 2017

0 references

1 reference