(Q71808694)

English

Lipopolysaccharide (LPS) down-regulates CD4 expression in primary human macrophages through induction of endogenous tumour necrosis factor (TNF) and IL-1 beta

scientific article published on 01 November 1995

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7586702%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

Lipopolysaccharide (LPS) down-regulates CD4 expression in primary human macrophages through induction of endogenous tumour necrosis factor (TNF) and IL-1 beta (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7586702%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

lipopolysaccharide

1 reference

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author name string

G Herbein

1

1 reference

Europe PubMed Central

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21 October 2019

A G Doyle

2

1 reference

Europe PubMed Central

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21 October 2019

L J Montaner

3

1 reference

Europe PubMed Central

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21 October 2019

S Gordon

4

1 reference

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21 October 2019

publication date

1 November 1995

1 reference

Europe PubMed Central

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21 October 2019

Clinical and Experimental Immunology

1 reference

Europe PubMed Central

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21 October 2019

102

1 reference

Europe PubMed Central

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21 October 2019

2

1 reference

Europe PubMed Central

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21 October 2019

430-437

1 reference

Europe PubMed Central

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21 October 2019

Disruption of the CD4-p56lck complex is required for rapid internalization of CD4

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-1 and tumor necrosis factor-alpha each up-regulate both the expression of IFN-gamma receptors and enhance IFN-gamma-induced HLA-DR expression on human monocytes and a human monocytic cell line (THP-1).

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of human immunodeficiency virus type 1 production in CD4+ T cells by an intracellular CD4 expressed under control of the viral long terminal repeat

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reconstitution of the subclass-specific expression of CD4 in thymocytes and peripheral T cells of transgenic mice: identification of a human CD4 enhancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type 1-infected individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 13 inhibits human immunodeficiency virus type 1 production in primary blood-derived human macrophages in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the human CD4 gene promoter: transcription from the CD4 gene core promoter is tissue-specific and is activated by Ets proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vpu-induced degradation of CD4: requirement for specific amino acid residues in the cytoplasmic domain of CD4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased signaling competence as a result of receptor overexpression: overexpression of CD4 reduces its ability to activate p56lck tyrosine kinase and to regulate T-cell antigen receptor expression in immature CD4+CD8+ thymocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4 cell surface downregulation in HIV-1 Nef transgenic mice is a consequence of intracellular sequestration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 induces tumour necrosis factor and IL-1 gene expression in primary human macrophages independent of productive infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-13 alters the activation state of murine macrophages in vitro: comparison with interleukin-4 and interferon-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A transcriptional silencer controls the developmental expression of the CD4 gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-10 inhibits initial reverse transcription of human immunodeficiency virus type 1 and mediates a virostatic latent state in primary blood-derived human macrophages in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-Leu-3/T4 antibodies react with cells of monocyte/macrophage and Langerhans lineage

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of surface antigens of a human monocyte cell line, U937, during incubation with T lymphocyte-conditioned medium: detection of T4 antigen and its presence on normal blood monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the L3T4-antigen in T cell activation. II. Inhibition of T cell activation by monoclonal anti-L3T4 antibodies in the absence of accessory cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of circulating T4+ monocytes in patients infected with HTLV-III.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human T lymphocytes and monocytes bear the same Leu-3(T4) antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient modulation and internalization of T4 antigen induced by phorbol esters.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of human monocytes on gelatin-coated surfaces

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of CD4 by antigenic activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human immunodeficiency virus infection of monocytic and T-lymphocytic cells: receptor modulation and differentiation induced by phorbol ester

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between CD4 and class II MHC molecules mediates cell adhesion

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated levels of circulating cachectin/tumor necrosis factor in patients with acquired immunodeficiency syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokines alter production of HIV-1 from primary mononuclear phagocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of CD4 membrane expression and CD4 mRNA during acute human immunodeficiency virus replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment with recombinant IFN-gamma decreases cell surface CD4 levels on peripheral blood monocytes and on myelomonocyte cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purified blood monocytes from HIV 1-infected patients produce high levels of TNF alpha and IL-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophages rapidly internalize their tumor necrosis factor receptors in response to bacterial lipopolysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferons and bacterial lipopolysaccharide protect macrophages from productive infection by human immunodeficiency virus in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depletion of the surface CD4 molecule by the envelope protein of human immunodeficiency virus expressed in a human CD4+ monocytoid cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 and tumor necrosis factor alpha can be induced from mononuclear phagocytes by human immunodeficiency virus type 1 binding to the CD4 receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variations in CD4 expression by human monocytes and macrophages and their relationships to infection with the human immunodeficiency virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Class II MHC molecules and the HIV gp 120 envelope protein interact with functionally distinct regions of the CD4 molecule

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4: collaborator in immune recognition and HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional and post-transcriptional regulation of TcR, CD4 and CD8 gene expression during activation of normal human T lymphocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In Vitro Infection of Monocytes with HIVBa-L. Effect on Cell Surface Expression of CD4, CD14, HLA-DR, and HLA-DQ

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage-tropic strains of human immunodeficiency virus type 1 utilize the CD4 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine immunoglobulin G anti-CD4 monoclonal antibodies bind to primary human monocytes and macrophages through Fc receptors as well as authentic CD4

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adhesion versus coreceptor function of CD4 and CD8: role of the cytoplasmic tail in coreceptor activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol esters down-regulate transcription and translation of the CD4 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4 and CD8 act as co-receptors during thymic selection of the T cell repertoire

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational analysis of the interaction between CD4 and class II MHC: class II antigens contact CD4 on a surface opposite the gp120-binding site

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4

1 reference

https://pubmed.ncbi.nlm.nih.gov/7586702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2249.1995.TB03801.X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7586702%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7586702%20AND%20SRC:MED&resulttype=core&format=json

21 October 2019

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