(Q71856538)

English

Modeling of serpin-protease complexes: antithrombin-thrombin, alpha 1-antitrypsin (358Met-->Arg)-thrombin, alpha 1-antitrypsin (358Met-->Arg)-trypsin, and antitrypsin-elastase

scientific article published on 01 November 1996

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scholarly article

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21 October 2019

Modeling of serpin-protease complexes: antithrombin-thrombin, alpha 1-antitrypsin (358Met-->Arg)-thrombin, alpha 1-antitrypsin (358Met-->Arg)-trypsin, and antitrypsin-elastase (English)

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21 October 2019

James C Whisstock

1

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21 October 2019

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object named as

Lesk AM

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21 October 2019

author name string

Carrell R

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21 October 2019

publication date

1 November 1996

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21 October 2019

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21 October 2019

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21 October 2019

288-303

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21 October 2019

Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Human plasma proteinase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Human alpha 1-proteinase inhibitor. Crystal structure analysis of two crystal modifications, molecular model and preliminary analysis of the implications for function

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Structural basis of latency in plasminogen activator inhibitor-1

1 reference

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21 January 2018

Biological implications of a 3 A structure of dimeric antithrombin

1 reference

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21 January 2018

The intact and cleaved human antithrombin III complex as a model for serpin-proteinase interactions

1 reference

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21 January 2018

Crystal structure of ovalbumin as a model for the reactive centre of serpins

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Serpin tertiary structure transformation

1 reference

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21 January 2018

On the size of the active site in proteases. I. Papain

1 reference

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21 January 2018

Effects of mutations in the hinge region of serpins

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Crystal structure of an uncleaved serpin reveals the conformation of an inhibitory reactive loop

1 reference

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21 January 2018

What do dysfunctional serpins tell us about molecular mobility and disease?

1 reference

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21 January 2018

Antithrombin Cambridge II, 384 Ala to Ser. Further evidence of the role of the reactive centre loop in the inhibitory function of the serpins

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Sequence alignment approach to pick up conformationally similar protein fragments

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

The contribution of the conserved hinge region residues of alpha1-antitrypsin to its reaction with elastase

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Structural transition of alpha 1-antitrypsin by a peptide sequentially similar to beta-strand s4A.

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Evidence for the extent of insertion of the active site loop of intact alpha 1 proteinase inhibitor in beta-sheet A

1 reference

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21 January 2018

Immunologic evidence for insertion of the reactive-bond loop of antithrombin into the A beta-sheet of the inhibitor during trapping of target proteinases

1 reference

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21 January 2018

Antithrombin Cambridge, 384 Ala to Pro: a new variant identified using the polymerase chain reaction

1 reference

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21 January 2018

Modeling the uncleaved serpin antichymotrypsin and its chymotrypsin complex

1 reference

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21 January 2018

Structural basis for serpin inhibitor activity

1 reference

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21 January 2018

Serpin-protease complexes are trapped as stable acyl-enzyme intermediates

1 reference

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21 January 2018

The inhibition mechanism of serpins. Evidence that the mobile reactive center loop is cleaved in the native protease-inhibitor complex.

1 reference

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21 January 2018

Structural basis of the activation and action of trypsin

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Molecular recognition. Conformational analysis of limited proteolytic sites and serine proteinase protein inhibitors

1 reference

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21 January 2018

The Protein Data Bank: a computer-based archival file for macromolecular structures

1 reference

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21 January 2018

Macromolecular marionettes

1 reference

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21 January 2018

The interpretation of protein structures: Estimation of static accessibility

1 reference

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21 January 2018

Trypsin complexed with alpha 1-proteinase inhibitor has an increased structural flexibility

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Do salt bridges stabilize proteins? A continuum electrostatic analysis.

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

A buried polar interaction imparts structural uniqueness in a designed heterodimeric coiled coil

1 reference

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21 January 2018

Conformational change in antithrombin induced by heparin probed with a monoclonal antibody against the 1C/4B region

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

COOH-terminal substitutions in the serpin C1 inhibitor that cause loop overinsertion and subsequent multimerization

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Crystal structure of cleaved bovine antithrombin III at 3.2 A resolution

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Crystal structure of plakalbumin, a proteolytically nicked form of ovalbumin. Its relationship to the structure of cleaved alpha-1-proteinase inhibitor

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Crystal structure of cleaved human alpha 1-antichymotrypsin at 2.7 A resolution and its comparison with other serpins

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Crystal structure of cleaved equine leucocyte elastase inhibitor determined at 1.95 A resolution

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-A resolution

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Three-dimensional structure of the complex between pancreatic secretory trypsin inhibitor (Kazal type) and trypsinogen at 1.8 Å resolution

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Alpha 1-proteinase inhibitor variant T345R. Influence of P14 residue on substrate and inhibitory pathways

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

C1 inhibitor hinge region mutations produce dysfunction by different mechanisms

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Kinetic studies on the interaction of alpha 1-proteinase inhibitor (Pittsburgh) with trypsin-like serine proteinases

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Effect of heparin on the glia-derived-nexin-thrombin interaction

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-0134%28199611%2926%3A3%3C288%3A%3AAID-PROT5%3E3.0.CO%3B2-A

21 January 2018

Identifiers

10.1002/(SICI)1097-0134(199611)26:3<288::AID-PROT5>3.0.CO;2-A

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21 October 2019

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