(Q71901236)

English

The staurosporine producing strain Streptomyces longisporoflavus produces metabolites related to K-252a. Proposal for biosynthetic intermediates of K-252a

scientific article published on 01 October 1996

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scholarly article

1 reference

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22 October 2019

The staurosporine producing strain Streptomyces longisporoflavus produces metabolites related to K-252a. Proposal for biosynthetic intermediates of K-252a (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8968403%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

Streptomyces longisporoflavus

1 reference

N,N-Dimethylstaurosporine

1 reference

1 reference

staurosporinone

1 reference

1 reference

1 reference

Staurosporine HCl

1 reference

1 reference

6-[(Isopropyloxy)methyl]-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one

1 reference

Streptomyces lividus

1 reference

Streptomyces hygroscopicus

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Streptomyces actuosus

1 reference

4-Hydroxyimino-3-methoxy-2-methyl-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one

1 reference

1 reference

author name string

Y Cai

1

1 reference

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22 October 2019

A Fredenhagen

2

1 reference

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22 October 2019

P Hug

3

1 reference

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22 October 2019

H H Peter

4

1 reference

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22 October 2019

publication date

1996

3 references

16 September 2022

16 September 2022

full work available at URL

https://www.jstage.jst.go.jp/article/antibiotics1968/49/10/49_10_1060/_pdf

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19 March 2024

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The Journal of Antibiotics

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22 October 2019

49

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22 October 2019

1060-1062

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22 October 2019

10

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22 October 2019

online access status

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19 March 2024

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access restriction status

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based on heuristic

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Further minor metabolites of staurosporine produced by a Streptomyces longisporoflavus strain

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A new alkaloid AM-2282 OF Streptomyces origin. Taxonomy, fermentation, isolation and preliminary characterization

2 references

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Biosynthesis of staurosporine, 2. Incorporation of tryptophan

1 reference

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UCN-01 and UCN-02, new selective inhibitors of protein kinase C. I. Screening, producing organism and fermentation

1 reference

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The structures of the novel protein kinase C inhibitors K-252a, b, c and d

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Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase

1 reference

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A new inhibitor of protein kinase C, RK-286C (4'-demethylamino-4'-hydroxystaurosporine). I. Screening, taxonomy, fermentation and biological activity.

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K-252b selectively potentiates cellular actions and trk tyrosine phosphorylation mediated by neurotrophin-3.

1 reference

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K-252a, a potent inhibitor of protein kinase C from microbial origin

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Identifiers

10.7164/ANTIBIOTICS.49.1060

1 reference

Europe PubMed Central

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22 October 2019

1 reference

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22 October 2019

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