(Q27097269)

K-252c (English)

19 October 2016

C₂₀H₁₃N₃O

1 reference

K-252c (English)

19 October 2016

C1C2=C3C4=CC=CC=C4NC3=C5C(=C2C(=O)N1)C6=CC=CC=C6N5

1 reference

Staurosporine Derivatives from the AscidianEudistomatoealensisand Its Predatory FlatwormPseudocerossp.∇

K-252c (English)

19 October 2016

3 references

Staurosporine Derivatives from the AscidianEudistomatoealensisand Its Predatory FlatwormPseudocerossp.∇

Further new staurosporine derivatives from the ascidian Eudistoma toealensis and its predatory flatworm Pseudoceros sp.

Nocardiopsis

1 reference

The structures of the novel protein kinase C inhibitors K-252a, b, c and d

Lycogala epidendrum

2 references

Isolation and synthesis of 3,4-bis(indol-3-yl)pyrrole-2,5-dicarboxylic acid derivatives from the slime mould Lycogala epidendrum

New cytotoxic bisindole alkaloids with protein tyrosine kinase inhibitory activity from a myxomycete Lycogala epidendrum

Eudistoma

1 reference

Staurosporine aglycone (K252-c) and arcyriaflavin A from the marine ascidian, Eudistoma sp.

Streptomyces longisporoflavus

4 references

Further minor metabolites of staurosporine produced by a Streptomyces longisporoflavus strain

Production of the staurosporine aglycon K-252c with a blocked mutant of the staurosporine producer strain Streptomyces longisporoflavus and by biotransformation of staurosporine with Streptomyces mediocidicus ATCC 13279

The staurosporine producing strain Streptomyces longisporoflavus produces metabolites related to K-252a. Proposal for biosynthetic intermediates of K-252a

A nitro analogue of staurosporine and other minor metabolites produced by a Streptomyces longisporoflavus strain

Streptomyces sanyensis

2 references

Antiamoebic Activities of Indolocarbazole Metabolites Isolated from Streptomyces sanyensis Cultures

Cloning, characterization and heterologous expression of the indolocarbazole biosynthetic gene cluster from marine-derived Streptomyces sanyensis FMA.

Identifiers

InChI

InChI=1S/C20H13N3O/c24-20-17-12(9-21-20)15-10-5-1-3-7-13(10)22-18(15)19-16(17)11-6-2-4-8-14(11)23-19/h1-8,22-23H,9H2,(H,21,24)

1 reference

MEXUTNIFSHFQRG-UHFFFAOYSA-N

K-252c (English)

19 October 2016

1 reference

K-252c (English)

19 October 2016

1 reference

staurosporine aglycone (K252-c) (English)

19 October 2016

1 reference

K-252c (English)

19 October 2016

1 reference

STAUROSPORINONE (English)

19 October 2016

1 reference

1 reference

Human Metabolome Database ID

6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one (English)

retrieved

19 October 2016

HMDB0260295

1 reference

based on heuristic

inferred from InChIKey

KNApSAcK ID

C00017791

1 reference

based on heuristic

inferred from InChIKey

Natural Product Atlas ID

NPA007264

1 reference

based on heuristic

inferred from InChIKey

0 references

0 references

1 reference

2R0P (English)

19 October 2016

1 reference