(Q72875655)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7987985%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

title

Biochemical effects of folate-based inhibitors of thymidylate synthase in MGH-U1 cells (English)

1 reference

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30 October 2019

4

C Erlichman

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30 October 2019

author name string

B Mitrovski

series ordinal

1

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30 October 2019

J Pressacco

series ordinal

2

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30 October 2019

S Mandelbaum

series ordinal

3

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30 October 2019

publication date

1 January 1994

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Cancer Chemotherapy and Pharmacology

30 October 2019

published in

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30 October 2019

volume

35

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30 October 2019

page(s)

109-114

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30 October 2019

issue

2

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https://scigraph.springernature.com/pub.10.1007/bf00686631

30 October 2019

exact match

0 references

cites work

Biochemical and cellular pharmacology of 1843U89, a novel benzoquinazoline inhibitor of thymidylate synthase

1 reference

12 December 2020

Quinazoline antifolates inhibiting thymidylate synthase: computer modelling of the N10 substituent

1 reference

12 December 2020

Modulation of anti-metabolite effects. Effects of thymidine on the efficacy of the quinazoline-based thymidylate synthetase inhibitor, CB3717

1 reference

12 December 2020

Comparative cytotoxicity of folate-based inhibitors of thymidylate synthase and 5-fluorouracil +/- leucovorin in MGH-U1 cells

1 reference

12 December 2020

Comparison of in vitro drug sensitivity by inhibition of tritium release from [5-3H]-2'-deoxyuridine and a clonogenic assay

1 reference

12 December 2020

ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study

1 reference

12 December 2020

The biochemical pharmacology of the thymidylate synthase inhibitor, 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583)

1 reference

12 December 2020

Rapid determination of thymidylate synthase activity and its inhibition in intact L1210 leukemia cells in vitro

1 reference

12 December 2020

Quinazoline antifolates inhibiting thymidylate synthase: 2-desamino derivatives with enhanced solubility and potency

1 reference

12 December 2020

An Isotopic Assay for Thymidylate Synthetase*

1 reference

12 December 2020

A phase I evaluation of the quinazoline antifolate thymidylate synthase inhibitor, N10-propargyl-5,8-dideazafolic acid, CB3717

1 reference

12 December 2020

Phase II study of the antifolate N10-propargyl-5,8-dideazafolic acid (CB 3717) in advanced breast cancer

1 reference

12 December 2020

Cytotoxicity of adriamycin in MGH-U1 cells grown as monolayer cultures, spheroids, and xenografts in immune-deprived mice

1 reference

12 December 2020

Recent preclinical and clinical studies with the thymidylate synthase inhibitor N10-propargyl-5,8-dideazafolic acid (CB 3717).

1 reference

12 December 2020

Quinazoline antifolate thymidylate synthase inhibitors: alkyl, substituted alkyl, and aryl substituents in the C2 position

1 reference

12 December 2020

Phase II study of the thymidylate synthetase inhibitor CB3717 (N10-propargyl-5,8-dideazafolic acid) in colorectal cancer

1 reference

12 December 2020

Activity of the thymidylate synthase inhibitor 2-desamino-N10-propargyl-5,8-dideazafolic acid and related compounds in murine (L1210) and human (W1L2) systems in vitro and in L1210 in vivo

1 reference

12 December 2020

Interaction of deoxyuridine with fluorouracil and dipyridamole in a human colon cancer cell line

1 reference

12 December 2020

Quinazoline antifolate thymidylate synthase inhibitors: heterocyclic benzoyl ring modifications

1 reference

12 December 2020

Symposium on the expanding role of folates and fluoropyrimidines in cancer chemotherapy

1 reference

12 December 2020

Induction of remission in hepatocellular carcinoma with a new thymidylate synthase inhibitor, CB3717

1 reference

12 December 2020

Potentiation of quinazoline antifolate (CB3717) toxicity by dipyridamole in human lung carcinoma, A549, cells

1 reference

12 December 2020

Mechanism of cell death following thymidylate synthase inhibition: 2'-deoxyuridine-5'-triphosphate accumulation, DNA damage, and growth inhibition following exposure to CB3717 and dipyridamole

1 reference

12 December 2020

Quinazoline antifolates inhibiting thymidylate synthase: synthesis of four oligo(L-gamma-glutamyl) conjugates of N10-propargyl-5,8-dideazafolic acid and their enzyme inhibition

1 reference

12 December 2020

Effects of 3'-azido-3'-deoxythymidine on the deoxynucleotide triphosphate pools of cultured human cells

1 reference

12 December 2020

Combination studies with 3'-azido-3'-deoxythymidine (AZT) plus ICI D1694. Cytotoxic and biochemical effects

1 reference

12 December 2020

Relationship of dUMP and free FdUMP pools to inhibition of thymidylate synthase by 5-fluorouracil

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00686631

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7987985%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

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