(Q72875669)

English

Interaction between endotoxin and the antitumour agent 5,6-dimethylxanthenone-4-acetic acid in the induction of tumour necrosis factor and haemorrhagic necrosis of colon 38 tumours

scientific article published on 01 January 1994

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7987993%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

Interaction between endotoxin and the antitumour agent 5,6-dimethylxanthenone-4-acetic acid in the induction of tumour necrosis factor and haemorrhagic necrosis of colon 38 tumours (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7987993%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

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author name string

L M Ching

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7987993%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

W R Joseph

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7987993%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

L Zhuang

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7987993%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

B C Baguley

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7987993%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

publication date

1 January 1994

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7987993%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

Cancer Chemotherapy and Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7987993%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

35

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7987993%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7987993%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

153-160

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7987993%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

https://scigraph.springernature.com/pub.10.1007/bf00686639

0 references

Immunomodulation of Natural Killer Cell Activity by Flavone Acetic Acid: Occurrence Via Induction of Interferon /beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of natural killer activity by Xanthenone analogues of flavone acetic acid: Relation with antitumour activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response to flavone acetic acid (NSC 347512) of primary and metastatic human colorectal carcinoma xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bacterial lipopolysaccharide stimulates protein tyrosine phosphorylation in macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavone-8-acetic acid augments systemic natural killer cell activity and synergizes with IL-2 for treatment of murine renal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro methods for screening agents with an indirect mechanism of antitumour activity: xanthenone analogues of flavone acetic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavone acetic acid potentiates the induction of endothelial procoagulant activity by tumour necrosis factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavone acetic acid (NSC 347512) induces haemorrhagic necrosis of mouse colon 26 and 38 tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the production of nitric oxide by activated macrophages treated with the antitumor agents flavone-8-acetic acid and xanthenone-4-acetic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between immune and vascular activities of xanthenone acetic acid antitumor agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination immunotherapy of cancer in a mouse model: synergism between tumor necrosis factor and other defense systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood flow failure as a major determinant in the antitumor action of flavone acetic acid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular collapse after flavone acetic acid: a possible mechanism of its anti-tumour action

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of tumor necrosis factor in flavone acetic acid-induced tumor vasculature shutdown

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of in vitro cytotoxicity of mouse peritoneal exudate cells by flavone acetic acid (NSC 347512)

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bacterial toxin-induced cytokine production studied at the single-cell level

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of macrophage tumouricidal activity by 5,6-dimethyl-xanthenone-4-acetic acid, a potent analogue of the antitumour agent flavone-8-acetic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of tumour growth on the macrophage response to the antitumour agent 5,6-dimethylxanthenone-4-acetic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavone acetic acid--preclinical and clinical activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant human tumor necrosis factor--I. Cytotoxic activity in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of tumor necrosis factor-alpha messenger RNA in human and murine cells by the flavone acetic acid analogue 5,6-dimethylxanthenone-4-acetic acid (NSC 640488).

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transfection of CD14 into 70Z/3 cells dramatically enhances the sensitivity to complexes of lipopolysaccharide (LPS) and LPS binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of antitumor effects of flavone acetic acid by cortisone

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific endotoxic lipopolysaccharide-binding receptors on murine splenocytes. III. Binding specificity and characterization

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Light-induced breakdown of flavone acetic acid and xanthenone analogues in solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Augmentation of natural killer activity, induction of IFN and development tumor immunity during the successful treatment of established murine renal cancer using flavone acetic acid and IL-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I trial of intravenously administered endotoxin (Salmonella abortus equi) in cancer patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of in vitro activity of cytotoxic drugs towards human carcinoma and leukaemia cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential antitumor agents. 61. Structure-activity relationships for in vivo colon 38 activity among disubstituted 9-oxo-9H-xanthene-4-acetic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma pharmacokinetics of the antitumour agents 5,6-dimethylxanthenone-4-acetic acid, xanthenone-4-acetic acid and flavone-8-acetic acid in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine induction and therapeutic synergy with interleukin-2 against murine renal and colon cancers by xanthenone-4-acetic acid derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of vascularised spheroids to investigate the action of flavone acetic acid on tumour blood vessels

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of T cells and tumour necrosis factor in antitumour activity and toxicity of flavone acetic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of tumor blood flow by flavone acetic acid: a possible component of therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An endotoxin-induced serum factor that causes necrosis of tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-gamma: mechanism of action and therapeutic potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gram-negative endotoxin: an extraordinary lipid with profound effects on eukaryotic signal transduction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-tumour activity of flavone acetic acid (NSC 347512) in mice--influence of immune status

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumour responses to flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid in immune deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the effects of flavone acetic acid, fostriecin, homoharringtonine and tumour necrosis factor alpha on colon 38 tumours in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immunological basis of endotoxin-induced tumor regression. Requirement for a pre-existing state of concomitant anti-tumor immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyporesponsiveness of macrophages from C3H/HeJ (endotoxin-resistant) mice to the antitumour agent flavone acetic acid (NSC 347512)

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between in vivo induction of cytokine gene expression by flavone acetic acid and strict dose dependency and therapeutic efficacy against murine renal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavone acetic acid: a novel agent with preclinical antitumor activity against colon adenocarcinoma 38 in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and function of lipopolysaccharide binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of flavone acetic acid (NSC 347,512) on splenic cytotoxic effector cells and their role in tumour necrosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavone acetic acid antitumour activity against a mouse pancreatic adenocarcinoma is mediated by natural killer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine phosphorylation of mitogen-activated protein kinases is necessary for activation of murine macrophages by natural and synthetic bacterial products

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of natural killer cell activity by the antitumour compound flavone acetic acid (NSC 347 512).

1 reference

https://pubmed.ncbi.nlm.nih.gov/7987993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00686639

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7987993%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7987993%20AND%20SRC:MED&resulttype=core&format=json

30 October 2019

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