(Q73048419)

English

Cyclin dependent kinase-5 (CDK-5) phosphorylates neurofilament heavy (NF-H) chain to generate epitopes for antibodies that label neurofilament accumulations in amyotrophic lateral sclerosis (ALS) and is present in affected motor neurones in ALS

scientific article published on 01 July 1999

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31 October 2019

Cyclin dependent kinase-5 (CDK-5) phosphorylates neurofilament heavy (NF-H) chain to generate epitopes for antibodies that label neurofilament accumulations in amyotrophic lateral sclerosis (ALS) and is present in affected motor neurones in ALS (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10509378%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

amyotrophic lateral sclerosis

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3

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P N Leigh

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31 October 2019

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N P Bajaj

1

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31 October 2019

S T al-Sarraj

2

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31 October 2019

V Anderson

4

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31 October 2019

C C Miller

5

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31 October 2019

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1 July 1999

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31 October 2019

Progress in Neuro-Psychopharmacology & Biological Psychiatry

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Europe PubMed Central

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31 October 2019

23

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31 October 2019

5

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31 October 2019

833-850

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31 October 2019

Phosphorylation of neurofilament heavy-chain side-arm fragments by cyclin-dependent kinase-5 and glycogen synthase kinase-3alpha in transfected cells

1 reference

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7 January 2021

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A novel hypothesis of lipofuscinogenesis and cellular aging based on interactions between oxidative stress and autophagocytosis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of endogenously phosphorylated KSP sites in the high-molecular-weight rat neurofilament protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Aberrant stress-induced phosphorylation of perikaryal neurofilaments

1 reference

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7 January 2021

based on heuristic

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Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cellular phosphorylation of neurofilament heavy-chain by cyclin-dependent kinase-5 masks the epitope for monoclonal antibody N52.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential cellular phosphorylation of neurofilament heavy side-arms by glycogen synthase kinase-3 and cyclin-dependent kinase-5.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased expression of cyclin-dependent kinase 5 in induced apoptotic neuron death in rat substantia nigra

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cross-linker system between neurofilaments, microtubules, and membranous organelles in frog axons revealed by the quick-freeze, deep-etching method

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Organization of mammalian neurofilament polypeptides within the neuronal cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Sequence and structure of the mouse gene coding for the largest neurofilament subunit.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Neuronal intermediate filaments

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Monoclonal antibodies distinguish several differentially phosphorylated states of the two largest rat neurofilament subunits (NF-H and NF-M) and demonstrate their existence in the normal nervous system of adult rats

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

bcl-2 protein expression in aged brain and neurodegenerative diseases

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Altered expression of bcl-2 and bax mRNA in amyotrophic lateral sclerosis spinal cord motor neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p35nck5a and cyclin-dependent kinase 5 colocalize in Lewy bodies of brains with Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin-dependent kinase 5 in Lewy body-like inclusions in anterior horn cells of a patient with sporadic amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of the high molecular weight neurofilament protein (NF-H) by Cdk5 and p35

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Altered tau and neurofilament proteins in neuro-degenerative diseases: diagnostic implications for Alzheimer's disease and Lewy body dementias

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitogen-activated protein kinases (Erk1,2) phosphorylate Lys-Ser-Pro (KSP) repeats in neurofilament proteins NF-H and NF-M.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin-dependent kinase 5 is associated with apoptotic cell death during development and tissue remodeling

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2899%2900044-5

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0278-5846(99)00044-5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10509378%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10509378%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

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