(Q73082732)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9037249%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Variable contribution of cytochromes P450 2D6, 2C9 and 3A4 to the 4-hydroxylation of tamoxifen by human liver microsomes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9037249%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

H K Crewe

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9037249%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

S W Ellis

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9037249%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

M S Lennard

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9037249%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

G T Tucker

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9037249%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

language of work or name

English

0 references

publication date

1 January 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9037249%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

published in

Biochemical Pharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9037249%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

53

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9037249%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9037249%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

page(s)

171-178

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9037249%20AND%20SRC:MED&resulttype=core&format=json

A risk-benefit assessment of tamoxifen therapy

1 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Tamoxifen: toxicities and drug resistance during the treatment and prevention of breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

A comparative study of tamoxifen metabolism in female rat, mouse and human liver microsomes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Identification of the cytochrome P450 IIIA family as the enzymes involved in the N-demethylation of tamoxifen in human liver microsomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

A monohydroxylated metabolite of tamoxifen with potent antioestrogenic activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Interindividual variation in the isomerization of 4-hydroxytamoxifen by human liver microsomes: involvement of cytochromes P450.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

The metabolism of tamoxifen by human liver microsomes is not mediated by cytochrome P450IID6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Genotoxicity of tamoxifen, tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450s

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Species differences in the covalent binding of [14C]tamoxifen to liver microsomes and the forms of cytochrome P450 involved

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Irreversible binding and metabolism of propranolol by human liver microsomes--relationship to polymorphic oxidation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Evidence that aspartic acid 301 is a critical substrate-contact residue in the active site of cytochrome P450 2D6.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

The expression of human cytochrome P450IA1 in the yeast Saccharomyces cerevisiae

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Characterization of the inhibition of P4501A2 by furafylline

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

High affinity phenacetin O-deethylase is catalysed specifically by cytochrome P450d (P450IA2) in the liver of the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Tolbutamide hydroxylation by human liver microsomes. Kinetic characterisation and relationship to other cytochrome P-450 dependent xenobiotic oxidations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Mephenytoin hydroxylation polymorphism: characterization of the enzymatic deficiency in liver microsomes of poor metabolizers phenotyped in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6 beta-hydroxylase cytochrome P-450 enzyme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Inhibition of rabbit liver microsomal oxidative metabolism and substrate binding by tamoxifen and the geometric isomers of clomiphene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Life threatening interaction between tamoxifen and warfarin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Life threatening interaction between tamoxifen and warfarin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900650-8

10.1016/S0006-2952(96)00650-8

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9037249%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference