(Q73195828)

English

A phosphatidylinositol 3-Kinase/p70 ribosomal S6 protein kinase pathway is required for the regulation by insulin of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase gene expression in human muscle cells

scientific article published on 01 November 1999

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Europe PubMed Central

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2 November 2019

A phosphatidylinositol 3-Kinase/p70 ribosomal S6 protein kinase pathway is required for the regulation by insulin of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase gene expression in human muscle cells (English)

1 reference

Europe PubMed Central

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2 November 2019

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2 November 2019

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M Roques

1

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2 November 2019

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1 November 1999

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2 November 2019

Journal of Biological Chemistry

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2 November 2019

274

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2 November 2019

48

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2 November 2019

34005-34010

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2 November 2019

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Phosphorylation and activation of p70s6k by PDK1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Phosphoinositide 3-kinases: a conserved family of signal transducers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Normal activation of p70 S6 kinase by insulin in cells overexpressing dominant negative 85kD subunit of phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Overexpression of a constitutively active form of phosphatidylinositol 3-kinase is sufficient to promote Glut 4 translocation in adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle from NIDDM subjects after in vivo insulin stimulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Insulin action in skeletal muscle from patients with NIDDM.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Acute regulation by insulin of phosphatidylinositol-3-kinase, Rad, Glut 4, and lipoprotein lipase mRNA levels in human muscle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Defective regulation of phosphatidylinositol-3-kinase gene expression in skeletal muscle and adipose tissue of non-insulin-dependent diabetes mellitus patients

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Analysis of the signaling pathway involved in the regulation of hexokinase II gene transcription by insulin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Effect of insulin on GLUT-4 mRNA and protein concentrations in skeletal muscle of patients with NIDDM and their first-degree relatives

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Insulin action in cultured human myoblasts: contribution of different signalling pathways to regulation of glycogen synthesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

The use of the reverse transcription-competitive polymerase chain reaction to investigate the in vivo regulation of gene expression in small tissue samples

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Insulin action and glucose metabolism in nondiabetic control and NIDDM subjects. Comparison using human skeletal muscle cell cultures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Phosphatidylinositol 3-Kinase, but Not p70/p85 Ribosomal S6 Protein Kinase, Is Required for the Regulation of Phosphoenolpyruvate Carboxykinase (PEPCK) Gene Expression by Insulin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Insulin regulation of glucose-6-phosphate dehydrogenase gene expression is rapamycin-sensitive and requires phosphatidylinositol 3-kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Central role for phosphatidylinositide 3-kinase in the repression of glucose-6-phosphatase gene transcription by insulin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Insulin stimulation of the fatty acid synthase promoter is mediated by the phosphatidylinositol 3-kinase pathway. Involvement of protein kinase B/Akt

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

The insulin-dependent biosynthesis of GLUT1 and GLUT3 glucose transporters in L6 muscle cells is mediated by distinct pathways. Roles of p21ras and pp70 S6 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Does mitogen-activated-protein kinase have a role in insulin action? The cases for and against

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Glucose transport in cultured human skeletal muscle cells. Regulation by insulin and glucose in nondiabetic and non-insulin-dependent diabetes mellitus subjects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Regulation of glycogen synthase activity in cultured skeletal muscle cells from subjects with type II diabetes: role of chronic hyperinsulinemia and hyperglycemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Glycogen synthase activity is reduced in cultured skeletal muscle cells of non-insulin-dependent diabetes mellitus subjects. Biochemical and molecular mechanisms

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Renal lactate metabolism and gluconeogenesis during insulin-induced hypoglycemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.48.34005

21 January 2018

Identifiers

10.1074/JBC.274.48.34005

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10567366%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10567366%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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