(Q73198136)

English

Mutagenesis of the dimer interface residues of tethered and untethered HIV-1 protease result in differential activity and suggest multiple mechanisms of compensation

scientific article published on 01 March 2003

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2 November 2019

Mutagenesis of the dimer interface residues of tethered and untethered HIV-1 protease result in differential activity and suggest multiple mechanisms of compensation (English)

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Europe PubMed Central

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2 November 2019

Steven C. Pettit

3

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2 November 2019

author name string

Sumana Choudhury

1

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2 November 2019

Lori Everitt

2

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2 November 2019

Andrew H Kaplan

4

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2 November 2019

publication date

1 March 2003

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2 November 2019

307

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2 November 2019

2

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2 November 2019

204-212

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2 November 2019

Inhibition of HIV protease activity by heterodimer formation

1 reference

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7 January 2021

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Synthetic "interface" peptides alter dimeric assembly of the HIV 1 and 2 proteases

1 reference

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7 January 2021

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beta-Galactosidase containing a human immunodeficiency virus protease cleavage site is cleaved and inactivated by human immunodeficiency virus protease

1 reference

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The use of native T7 DNA polymerase for site-directed mutagenesis

1 reference

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7 January 2021

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Crystal structure of a tethered dimer of HIV-1 proteinase complexed with an inhibitor

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

X-ray structure of a tethered dimer for HIV-1 protease

1 reference

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7 January 2021

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Stability and activity of human immunodeficiency virus protease: comparison of the natural dimer with a homologous, single-chain tethered dimer

1 reference

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7 January 2021

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Proteolytic processing mechanisms of a miniprecursor of the aspartic protease of human immunodeficiency virus type 1.

1 reference

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The tac promoter: a functional hybrid derived from the trp and lac promoters

1 reference

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7 January 2021

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Design, activity, and 2.8 A crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease

1 reference

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7 January 2021

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Structure of equine infectious anemia virus proteinase complexed with an inhibitor

1 reference

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7 January 2021

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Characterization of ribosomal frameshifting in HIV-1 gag-pol expression

1 reference

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7 January 2021

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Structure at 2.5-A resolution of chemically synthesized human immunodeficiency virus type 1 protease complexed with a hydroxyethylene-based inhibitor

1 reference

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7 January 2021

based on heuristic

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Human immunodeficiency virus proteinase dimer as component of the viral polyprotein prevents particle assembly and viral infectivity

1 reference

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7 January 2021

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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7 January 2021

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Complete mutagenesis of the HIV-1 protease

1 reference

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7 January 2021

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inferred from DOI database lookup

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7 January 2021

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Kinetics and mechanism of autoprocessing of human immunodeficiency virus type 1 protease from an analog of the Gag-Pol polyprotein

1 reference

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7 January 2021

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Engineering human immunodeficiency virus 1 protease heterodimers as macromolecular inhibitors of viral maturation

1 reference

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7 January 2021

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The HIV-1 protease as enzyme and substrate: mutagenesis of autolysis sites and generation of a stable mutant with retained kinetic properties.

1 reference

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7 January 2021

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Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1

1 reference

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7 January 2021

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Unfolding kinetics of tryptophan side chains in the dimerization and hinge regions of HIV-I protease tethered dimer by real time NMR spectroscopy.

1 reference

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7 January 2021

based on heuristic

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Activities of precursor and tethered dimer forms of HIV proteinase

1 reference

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7 January 2021

based on heuristic

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Complete nucleotide sequences of functional clones of the AIDS virus

1 reference

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7 January 2021

based on heuristic

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Structure of the protease from simian immunodeficiency virus: complex with an irreversible nonpeptide inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2802%2900080-6

7 January 2021

based on heuristic

inferred from DOI database lookup

The inhibition of HIV-1 protease by interface peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0042-6822%2802%2900080-6

7 January 2021

based on heuristic

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The structural stability of the HIV-1 protease

1 reference

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7 January 2021

based on heuristic

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Activity of tethered human immunodeficiency virus 1 protease containing mutations in the flap region of one subunit

1 reference

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7 January 2021

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Database of three-dimensional structures of HIV proteinases

1 reference

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7 January 2021

based on heuristic

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Structural alignment of retroviral protease sequences

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7 January 2021

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Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease

1 reference

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7 January 2021

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Partial inhibition of the human immunodeficiency virus type 1 protease results in aberrant virus assembly and the formation of noninfectious particles.

1 reference

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inferred from DOI database lookup

Identifiers

10.1016/S0042-6822(02)00080-6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12667791%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12667791%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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