(Q73253189)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9113088%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Mechanisms of acquired resistance to modulation of 5-fluorouracil by leucovorin in HCT-8 human ileocecal carcinoma cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9113088%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

K Lu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9113088%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

J J McGuire

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9113088%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

H K Slocum

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9113088%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Y M Rustum

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9113088%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

language of work or name

English

0 references

publication date

1 March 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9113088%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

published in

Biochemical Pharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9113088%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

volume

53

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9113088%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9113088%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

page(s)

689-696

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9113088%20AND%20SRC:MED&resulttype=core&format=json

Structures of reversible and irreversible complexes of thymidylate synthetase and fluorinated pyrimidine nucleotides.

2 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

A randomized trial of fluorouracil and folinic acid in patients with metastatic colorectal carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

The modulation of fluorouracil with leucovorin in metastatic colorectal carcinoma: a prospective randomized phase III trial. Gastrointestinal Tumor Study Group

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

Prospective randomized comparison of fluorouracil versus fluorouracil and high-dose continuous infusion leucovorin calcium for the treatment of advanced measurable colorectal cancer in patients previously unexposed to chemotherapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

Biochemical factors affecting the tightness of 5-fluorodeoxyuridylate binding to human thymidylate synthetase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

Effect of polyglutamylation of 5,10-methylenetetrahydrofolate on the binding of 5-fluoro-2'-deoxyuridylate to thymidylate synthase purified from a human colon adenocarcinoma xenograft

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

Interactions of pig liver serine hydroxymethyltransferase with methyltetrahydropteroylpolyglutamate inhibitors and with tetrahydropteroylpolyglutamate substrates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

New colorimetric cytotoxicity assay for anticancer-drug screening

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

Tissue folate polyglutamate chain length determination by electrophoresis as thymidylate synthase-fluorodeoxyuridylate ternary complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

Rapid determination of thymidylate synthase activity and its inhibition in intact L1210 leukemia cells in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

Mechanisms of resistance to N-[5-[N-(3, 4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N-methylamino]-2-thenoyl]-L-glutamic acid (ZD1694), a folate-based thymidylate synthase inhibitor, in the HCT-8 human ileocecal adenocarcinoma cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

Effect of 5,10-methylenetetrahydrofolate on the dissociation of 5-fluoro-2'-deoxyuridylate from thymidylate synthetase: evidence for an ordered mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

Tissue folylpolyglutamate chain-length characterization by electrophoresis as thymidylate synthetase-fluorodeoxyuridylate ternary complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

The effect of dose and interval between 5-fluorouracil and leucovorin on the formation of thymidylate synthase ternary complex in human cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

In vitro enhancement of fluoropyrimidine-induced cytotoxicity by leucovorin in colorectal and gastric carcinoma cell lines but not in non-small-cell lung carcinoma cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

Wide range for optimal concentration of folinic acid in fluorouracil modulation--experimental data on human tumour cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

Lack of effectiveness of combined 5-fluorouracil and leucovorin in patients with 5-fluorouracil-resistant advanced colorectal cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

Reversal of resistance to doxifluridine and fluorouracil in metastatic colorectal cancer: the role of high-dose folinic acid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

Aberrant cell cycle inhibition pattern in human colon carcinoma cell lines after exposure to 5-fluorouracil

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2896%2900900-8

10.1016/S0006-2952(96)00900-8

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9113088%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference