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Oncogenic insertional mutations in the P-loop of Ras are overactive in MAP kinase signaling
scientific article published on 01 November 2000
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Europe PubMed Central
PubMed publication ID
11103938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
title
Oncogenic insertional mutations in the P-loop of Ras are overactive in MAP kinase signaling
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11103938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
author name string
Klockow B
series ordinal
1
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Europe PubMed Central
PubMed publication ID
11103938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
Ahmadian MR
series ordinal
2
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Europe PubMed Central
PubMed publication ID
11103938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103938%20AND%20SRC:MED&resulttype=core&format=json
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2 November 2019
Block C
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3
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Europe PubMed Central
PubMed publication ID
11103938
reference URL
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2 November 2019
Wittinghofer A
series ordinal
4
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Europe PubMed Central
PubMed publication ID
11103938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103938%20AND%20SRC:MED&resulttype=core&format=json
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2 November 2019
language of work or name
English
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publication date
1 November 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11103938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11103938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
volume
19
1 reference
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Europe PubMed Central
PubMed publication ID
11103938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
issue
47
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11103938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
page(s)
5367-5376
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11103938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
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Activation of Ha-ras p21 by substitution, deletion, and insertion mutations
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7 January 2021
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The RafC1 cysteine-rich domain contains multiple distinct regulatory epitopes which control Ras-dependent Raf activation
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7 January 2021
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Dominant inhibitory mutations in the Mg(2+)-binding site of RasH prevent its activation by GTP
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Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras
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7 January 2021
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Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: the C-terminal domain of GAP is not sufficient for full activity
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Mutational activation of oncogenes in animal model systems of carcinogenesis
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7 January 2021
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Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase
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Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor
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Kinetics of interaction of nucleotides with nucleotide-free H-ras p21
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Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.
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GTP-dependent association of Raf-1 with Ha-Ras: identification of Raf as a target downstream of Ras in mammalian cells.
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Interactions between Ras proteins and their effectors
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7 January 2021
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Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins
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Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase
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The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue
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Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation
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Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis
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Substrate and Product Structural Requirements for Binding of Nucleotides to H-ras p21: The Mechanism of Discrimination between Guanosine and Adenosine Nucleotides
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7 January 2021
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1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Molecular cloning of two types of GAP complementary DNA from human placenta
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7 January 2021
based on heuristic
inferred from DOI database lookup
Complex formation between RAS and RAF and other protein kinases
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Mammalian Ras interacts directly with the serine/threonine kinase Raf
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203909
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7 January 2021
based on heuristic
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Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203909
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7 January 2021
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inferred from DOI database lookup
Multiple Ras functions can contribute to mammalian cell transformation
1 reference
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7 January 2021
based on heuristic
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A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ligand binding is the principal determinant of stability for the p21(H)-ras protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203909
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7 January 2021
based on heuristic
inferred from DOI database lookup
Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203909
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1203909
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11103938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
Dimensions Publication ID
1050523916
0 references
PubMed publication ID
11103938
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11103938
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11103938%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
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