(Q73272071)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10597902%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

In vitro inhibition of human liver drug metabolizing enzymes by second generation antihistamines (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10597902%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

author name string

J M Nicolas

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10597902%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

R Whomsley

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10597902%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

P Collart

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10597902%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

J Roba

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10597902%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

publication date

1 November 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10597902%20AND%20SRC:MED&resulttype=core&format=json

Chemico-biological Interactions

2 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10597902%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

volume

123

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10597902%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10597902%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

page(s)

63-79

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10597902%20AND%20SRC:MED&resulttype=core&format=json

Identification of human liver cytochrome P450 enzymes that metabolize the nonsedating antihistamine loratadine. Formation of descarboethoxyloratadine by CYP3A4 and CYP2D6.

2 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Pharmacokinetic-pharmacodynamic relationships of H1-antihistamines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

A study of the interaction between dirithromycin and astemizole in healthy adults

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Inhibition of terfenadine metabolism in vitro by azole antifungal agents and by selective serotonin reuptake inhibitor antidepressants: relation to pharmacokinetic interactions in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Applications of primary human hepatocytes in the evaluation of pharmacokinetic drug-drug interactions: evaluation of model drugs terfenadine and rifampin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Cytochrome P-450 monooxygenase activities in human and rat liver microsomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Measurement of protein using bicinchoninic acid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Determination of tolbutamide hydroxylation in rat liver microsomes by high-performance liquid chromatography: effect of psychoactive drugs on in vitro activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4'-hydroxylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Inhibition of human cytochrome P450 2D6 (CYP2D6) by methadone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

43 Measurement of steroid hydroxylation reactions by high-performance liquid chromatography as indicator of P450 identity and function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Sulphation and glucuronidation of paracetamol in human liver: assay conditions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Sulphation and glucuronidation of ethinyloestradiol in human liver in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

4-Nitrophenol UDPglucuronyltransferase (rat liver)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Cooperativity in oxidations catalyzed by cytochrome P450 3A4.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site-directed mutagenesis experiments in the CYP2C subfamily

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

The histamine H1-receptor antagonist binding site. A stereoselective pharmacophoric model based upon (semi-)rigid H1-antagonists and including a known interaction site on the receptor.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Evidence that aspartic acid 301 is a critical substrate-contact residue in the active site of cytochrome P450 2D6.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Speculations on the substrate structure-activity relationship (SSAR) of cytochrome P450 enzymes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Inhibition of human and rabbit liver steroid and xenobiotic UDP-glucuronosyltransferases by tertiary amine drugs--implications for adverse drug reactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Effect of zileuton on theophylline pharmacokinetics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Pharmacokinetic Optimisation of Histamine H1-Receptor Antagonist Therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Mizolastine: a review of its use in allergic rhinitis and chronic idiopathic urticaria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Astemizole. A review of its pharmacodynamic properties and therapeutic efficacy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Loratadine. A preliminary review of its pharmacodynamic properties and therapeutic efficacy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Terfenadine. An updated review of its pharmacological properties and therapeutic efficacy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

Drug interactions and the cytochrome P450 system. The role of cytochrome P450 2C19.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900131-3

10.1016/S0009-2797(99)00131-3

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10597902%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference