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Viral infection results in massive CD8+ T cell expansion and mortality in vaccinated perforin-deficient mice
scientific article published on 01 April 2003
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12705850
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705850%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
title
Viral infection results in massive CD8+ T cell expansion and mortality in vaccinated perforin-deficient mice
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12705850
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705850%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
author
John T. Harty
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12705850
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705850%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
author name string
Vladimir P Badovinac
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12705850
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705850%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
Sara E Hamilton
series ordinal
2
1 reference
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Europe PubMed Central
PubMed publication ID
12705850
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705850%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
publication date
1 April 2003
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12705850
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705850%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
published in
Immunity
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12705850
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705850%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
volume
18
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12705850
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705850%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
issue
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12705850
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705850%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
page(s)
463-474
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12705850
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705850%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
cites work
Phenotypic analysis of antigen-specific T lymphocytes
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7 January 2021
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Intracellular staining for TNF and IFN-gamma detects different frequencies of antigen-specific CD8(+) T cells
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Crossref
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7 January 2021
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Cutting edge: OFF cycling of TNF production by antigen-specific CD8+ T cells is antigen independent
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7 January 2021
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Regulation of antigen-specific CD8+ T cell homeostasis by perforin and interferon-gamma.
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7 January 2021
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Programmed contraction of CD8(+) T cells after infection.
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Aplastic anemia rescued by exhaustion of cytokine-secreting CD8+ T cells in persistent infection with lymphocytic choriomeningitis virus
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Expression and phosphorylation of the Listeria monocytogenes ActA protein in mammalian cells
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Massive expansion of antigen-specific CD8+ T cells during an acute virus infection
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Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes.
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Differential sensitivity of naive and memory CD8+ T cells to apoptosis in vivo.
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Influence of effector molecules on the CD8(+) T cell response to infection
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CD8+ T Cell Effector Mechanisms in Resistance to Infection
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Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory
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Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells
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Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
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Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo
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7 January 2021
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Homeostatic regulation of CD8+ T cells by perforin
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7 January 2021
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Activated and memory CD8+ T cells can be distinguished by their cytokine profiles and phenotypic markers.
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Rapid on/off cycling of cytokine production by virus-specific CD8+ T cells
1 reference
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Crossref
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7 January 2021
based on heuristic
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Differences in affinity of binding of lymphocytic choriomeningitis virus strains to the cellular receptor alpha-dystroglycan correlate with viral tropism and disease kinetics
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900079-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Perforin gene defects in familial hemophagocytic lymphohistiocytosis.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900079-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Functional significance of the perforin/granzyme cell death pathway
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900079-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
CD8(+)-T-cell response to secreted and nonsecreted antigens delivered by recombinant Listeria monocytogenes during secondary infection
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900079-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900079-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Immune function in mice lacking the perforin gene
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900079-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: antilisterial activity of CD8+ T cells derived from TNF-deficient and TNF/perforin double-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900079-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Viral immune evasion due to persistence of activated T cells without effector function
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900079-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1074-7613(03)00079-7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12705850
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705850%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
PubMed publication ID
12705850
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12705850
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12705850%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
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