(Q73355703)

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Relationships between exposure, cell loss and proliferation, and manifestation of Hprt mutant T cells following treatment of preweanling, weanling, and adult male mice with N-ethyl-N-nitrosourea

scientific article published on 01 December 1999

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3 November 2019

Relationships between exposure, cell loss and proliferation, and manifestation of Hprt mutant T cells following treatment of preweanling, weanling, and adult male mice with N-ethyl-N-nitrosourea (English)

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3 November 2019

Vernon E Walker

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V E Walker

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3 November 2019

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I M Jones

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3 November 2019

T L Crippen

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Q Meng

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M J Bauer

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A A Reilly

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A D Tates

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J Nakamura

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P B Upton

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T R Skopek

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1 December 1999

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3 November 2019

Mutation Research

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3 November 2019

A study of the frequency of sister-chromatid exchange and of thioguanine-resistant cells in mouse spleen lymphocytes after in vivo exposure to ethylnitrosourea.

1 reference

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7 January 2021

A method to quantify spontaneous and in vivo induced thioguanine-resistant mouse lymphocytes

1 reference

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7 January 2021

Factors that affect the frequency of thioguanine-resistant lymphocytes in mice following exposure to ethylnitrosourea

1 reference

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7 January 2021

Cloned mouse lymphocytes permit analysis of somatic mutations that occur in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900180-3

7 January 2021

Measurement of in vivo mutant frequency in lymphocytes in the mouse

1 reference

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7 January 2021

Induction of 6-thioguanine-resistant lymphocytes in Fischer 344 rats following in vivo exposure to N-ethyl-N-nitrosourea and cyclophosphamide.

1 reference

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7 January 2021

The effect of time after treatment, treatment schedule and animal age on the frequency of 6-thioguanine-resistant T-lymphocytes induced in Fischer 344 rats by N-ethyl-N-nitrosourea.

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900180-3

7 January 2021

Use of a T-lymphocyte clonal assay for determining HPRT mutant frequencies in individual rats

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900180-3

7 January 2021

Development of a cloning assay with high cloning efficiency to detect induction of 6-thioguanine-resistant lymphocytes in spleen of adult mice following in vivo inhalation exposure to 1,3-butadiene

1 reference

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7 January 2021

Enumeration of 6-thioguanine-resistant T-lymphocytes in the peripheral blood of nonhuman primates (cynomolgus monkeys).

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900180-3

7 January 2021

T-cell cloning to detect the mutant 6-thioguanine-resistant lymphocytes present in human peripheral blood

1 reference

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7 January 2021

Measurement of in vivo mutations in human lymphocytes

1 reference

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7 January 2021

Thymus cell migration. Quantitative aspects of cellular traffic from the thymus to the periphery in mice

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7 January 2021

Mutant manifestation: the time factor in somatic mutagenesis

1 reference

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7 January 2021

Mutagenicity of 1,3-butadiene at the Hprt locus of T-lymphocytes following inhalation exposures of female mice and rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900180-3

7 January 2021

Comparison of the mutagenic potency of 1,3-butadiene at the hprt locus of T-lymphocytes following inhalation exposure of female B6C3F1 mice and F344 rats

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900180-3

7 January 2021

Mutational spectrum at the Hprt locus in splenic T cells of B6C3F1 mice exposed to N-ethyl-N-nitrosourea

1 reference

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7 January 2021

Mutagenicity of butadiene and its epoxide metabolites: II. Mutational spectra of butadiene, 1,2-epoxybutene and diepoxybutane at the hprt locus in splenic T cells from exposed B6C3F1 mice.

1 reference

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7 January 2021

In vivo mutagenicity of ethylene oxide at the hprt locus in T-lymphocytes of B6C3F1 lacI transgenic mice following inhalation exposure.

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900180-3

7 January 2021

Comparison of induction of hprt mutations by 1,3-butadiene and/or its metabolites 1,2-epoxybutene and 1,2,3,4-diepoxybutane in lymphocytes from spleen of adult male mice and rats in vivo

1 reference

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7 January 2021

Ascorbic acid (vitamin C) modulates the mutagenic effects produced by an alkylating agent in vivo.

1 reference

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7 January 2021

Induction of hprt gene mutations in splenic T-lymphocytes from the rat exposed in vivo to DNA methylating agents is correlated with formation of O6-methylguanine in bone marrow and not in the spleen

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900180-3

7 January 2021

Use of T-cell receptor gene probes to quantify the in vivo hprt mutations in human T-lymphocytes

1 reference

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7 January 2021

Genetic instability in human T-lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900180-3

7 January 2021

Age dependent selection against HPRT deficient T lymphocytes in the HPRT+/- heterozygous mouse.

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900180-3

7 January 2021

Mutagenicity of the racemic mixtures of butadiene monoepoxide and butadiene diepoxide at the Hprt locus of T-lymphocytes following inhalation exposures of female mice and rats

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900180-3

7 January 2021

Toxicology and epidemiology of 1,3-butadiene

1 reference

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7 January 2021

Identifiers

10.1016/S0027-5107(99)00180-3

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Europe PubMed Central

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3 November 2019

1 reference

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3 November 2019

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