(Q73409121)

English

Mitomycin C linked to DNA minor groove binding agents: synthesis, reductive activation, DNA binding and cross-linking properties and in vitro antitumor activity

scientific article published on 01 December 1999

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10658576%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Mitomycin C linked to DNA minor groove binding agents: synthesis, reductive activation, DNA binding and cross-linking properties and in vitro antitumor activity (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10658576%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10658576%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

author name string

T A Das

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10658576%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

M Tomasz

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10658576%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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1 December 1999

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Europe PubMed Central

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3 November 2019

number of pages

14

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Bioorganic & Medicinal Chemistry

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Europe PubMed Central

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3 November 2019

7

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Europe PubMed Central

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3 November 2019

12

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10658576%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

2713-2726

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10658576%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

The mitomycin bioreductive antitumor agents: cross-linking and alkylation of DNA as the molecular basis of their activity

1 reference

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7 January 2021

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Mitomycin-C as a prototype bioreductive alkylating agent: in vitro studies of metabolism and cytotoxicity

1 reference

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7 January 2021

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Mitomycin C as an adjunct to postoperative radiation therapy in squamous cell carcinoma of the head and neck: Results from two randomized clinical trials

1 reference

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7 January 2021

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Mitomycin C-DNA adducts generated by DT-diaphorase. Revised mechanism of the enzymatic reductive activation of mitomycin C

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Bioreductive activation of mitomycin C by DT-diaphorase

1 reference

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7 January 2021

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Binding of 2,7-diaminomitosene to DNA: model for the precovalent recognition of DNA by activated mitomycin C

1 reference

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7 January 2021

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Noncovalent binding of a mitomycin C metabolite, 2,7-diaminomitosene, to duplex DNA

1 reference

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7 January 2021

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Metabolic activation of mitomycin C by liver microsomes and nuclei

1 reference

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7 January 2021

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Nonintercalating DNA-binding ligands: specificity of the interaction and their use as tools in biophysical, biochemical and biological investigations of the genetic material

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900223-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Sequence-Specific DNA Minor Groove Binders. Design and Synthesis of Netropsin and Distamycin Analogues

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

DNA sequence-specific adenine alkylation by the novel antitumor drug tallimustine (FCE 24517), a benzoyl nitrogen mustard derivative of distamycin

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Development of new mitomycin C and porfiromycin analogs

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Optical absorbance and fluorescence techniques for measuring DNA-drug interactions

1 reference

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7 January 2021

based on heuristic

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Structure-activity relationship of a series of C-terminus modified aminoalkyl, diaminoalkyl- and anilino-containing analogues of the benzoic acid mustard distamycin derivative tallimustine: synthesis, DNA binding and cytotoxicity studies

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

An agarose gel method for the determination of DNA interstrand crosslinking applicable to the measurement of the rate of total and "second-arm" crosslink reactions

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900223-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis, DNA-binding properties, and antitumor activity of novel distamycin derivatives.

1 reference

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7 January 2021

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Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900223-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Sequence specificity of alkylation for a series of nitrogen mustard-containing analogues of distamycin of increasing binding site size: evidence for increased cytotoxicity with enhanced sequence specificity.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900223-0

7 January 2021

based on heuristic

inferred from DOI database lookup

Reductive activation of mitomycin C

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900223-0

7 January 2021

based on heuristic

inferred from DOI database lookup

An NMR study of [d(CGCGAATTCGCG)]2 containing an interstrand cross-link derived from a distamycin-pyrrole conjugate

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis and evaluation of nitro 5-deazaflavin-pyrrolecarboxamide(s) hybrid molecules as novel DNA targeted bioreductive antitumor agents.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0896%2899%2900223-0

7 January 2021

based on heuristic

inferred from DOI database lookup

In vitro cytotoxicity of GC sequence directed alkylating agents related to distamycin

1 reference

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7 January 2021

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inferred from DOI database lookup

Identifiers

10.1016/S0968-0896(99)00223-0

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10658576%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10658576%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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