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The hammerhead ribozyme
scientific article published on 01 January 1999
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scholarly article
1 reference
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Europe PubMed Central
PubMed ID
11169382
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11169382%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
title
The hammerhead ribozyme
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11169382
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11169382%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
author name string
Eckstein F
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11169382
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11169382%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
Bramlage B
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11169382
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11169382%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
publication date
1 January 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
11169382
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11169382%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
published in
Biopolymers
1 reference
stated in
Europe PubMed Central
PubMed ID
11169382
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11169382%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
volume
52
1 reference
stated in
Europe PubMed Central
PubMed ID
11169382
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11169382%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed ID
11169382
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11169382%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
page(s)
147-154
1 reference
stated in
Europe PubMed Central
PubMed ID
11169382
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11169382%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
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Nucleic acid enzymes
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21 January 2018
The complete atomic structure of the large ribosomal subunit at 2.4 A resolution
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21 January 2018
One sequence, two ribozymes: implications for the emergence of new ribozyme folds
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21 January 2018
Small catalytic RNAs
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21 January 2018
A small catalytic oligoribonucleotide
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21 January 2018
Simple RNA enzymes with new and highly specific endoribonuclease activities
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21 January 2018
Designing ribozymes for the inhibition of gene expression
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21 January 2018
Ribozymes, genomics and therapeutics
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21 January 2018
Three-dimensional structure of a hammerhead ribozyme
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21 January 2018
The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage
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21 January 2018
Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme
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21 January 2018
The structural basis of hammerhead ribozyme self-cleavage
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21 January 2018
The structure, function and application of the hammerhead ribozyme
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21 January 2018
Crystallographic structures of the hammerhead ribozyme: relationship to ribozyme folding and catalysis
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21 January 2018
Structure, folding and catalysis of the small nucleolytic ribozymes
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retrieved
21 January 2018
Ion-induced folding of the hammerhead ribozyme: a fluorescence resonance energy transfer study
1 reference
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21 January 2018
RNA folding and misfolding of the hammerhead ribozyme.
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21 January 2018
Mg(2+)-dependent conformational changes in the hammerhead ribozyme
1 reference
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21 January 2018
Mechanisms of Ribozyme-Mediated RNA Cleavage
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21 January 2018
The Hydrolysis of RNA: From Theoretical Calculations to the Hammerhead Ribozyme-Mediated Cleavage of RNA
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retrieved
21 January 2018
Identification of the hammerhead ribozyme metal ion binding site responsible for rescue of the deleterious effect of a cleavage site phosphorothioate
1 reference
stated in
Crossref
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retrieved
21 January 2018
Does a single metal ion bridge the A-9 and scissile phosphate groups in the catalytically active hammerhead ribozyme structure?
1 reference
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Crossref
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retrieved
21 January 2018
A further investigation and reappraisal of the thio effect in the cleavage reaction catalyzed by a hammerhead ribozyme
1 reference
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retrieved
21 January 2018
Evidence for a hydroxide ion bridging two magnesium ions at the active site of the hammerhead ribozyme
1 reference
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retrieved
21 January 2018
The hammerhead, hairpin and VS ribozymes are catalytically proficient in monovalent cations alone
1 reference
stated in
Crossref
reference URL
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retrieved
21 January 2018
Crystallization and structure determination of a hepatitis delta virus ribozyme: use of the RNA-binding protein U1A as a crystallization module
1 reference
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21 January 2018
Imidazole rescue of a cytosine mutation in a self-cleaving ribozyme
1 reference
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Crossref
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21 January 2018
General acid-base catalysis in the mechanism of a hepatitis delta virus ribozyme
1 reference
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21 January 2018
The structural basis of ribosome activity in peptide bond synthesis
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21 January 2018
A single adenosine with a neutral pKa in the ribosomal peptidyl transferase center
1 reference
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Crossref
reference URL
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retrieved
21 January 2018
Metal ions in ribozyme folding and catalysis
1 reference
stated in
Crossref
reference URL
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retrieved
21 January 2018
Extending the cleavage rules for the hammerhead ribozyme: mutating adenosine15.1 to inosine15.1 changes the cleavage site specificity from N16.2U16.1H17 to N16.2C16.1H17.
1 reference
stated in
Crossref
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21 January 2018
AUA-cleaving hammerhead ribozymes: attempted selection for improved cleavage
1 reference
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21 January 2018
Isolation of hammerhead ribozymes with altered core sequences by in vitro selection
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Crossref
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21 January 2018
Attempts to obtain more efficient GAC-cleaving hammerhead ribozymes by in vitro selection
1 reference
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Crossref
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21 January 2018
In vitro selection of a purine nucleotide-specific hammerheadlike ribozyme
1 reference
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Crossref
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retrieved
21 January 2018
In vitro evolution of the hammerhead ribozyme to a purine-specific ribozyme using mutagenic PCR with two nucleotide analogues
1 reference
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Crossref
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21 January 2018
Kinetic Characterization of Ribonuclease-Resistant 2′-Modified Hammerhead Ribozymes
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21 January 2018
A nuclease-resistant protein kinase C alpha ribozyme blocks glioma cell growth.
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21 January 2018
In vitro selection of a novel nuclease-resistant RNA phosphodiesterase
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21 January 2018
Synthesis and Properties of Diuridine Phosphate Analogues Containing Thio and Amino Modifications
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21 January 2018
Optimizing the cell efficacy of synthetic ribozymes. Site selection and chemical modifications of ribozymes targeting the proto-oncogene c-myb.
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21 January 2018
Oligonucleotide scanning of native mRNAs in extracts predicts intracellular ribozyme efficiency: ribozyme-mediated reduction of the murine DNA methyltransferase
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retrieved
21 January 2018
A theoretical approach to select effective antisense oligodeoxyribonucleotides at high statistical probability
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retrieved
21 January 2018
Predicting oligonucleotide affinity to nucleic acid targets
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21 January 2018
RNA accessibility prediction: a theoretical approach is consistent with experimental studies in cell extracts
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Crossref
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21 January 2018
Cleavage of highly structured viral RNA molecules by combinatorial libraries of hairpin ribozymes. The most effective ribozymes are not predicted by substrate selection rules
1 reference
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21 January 2018
Ribozymes and the anti-gene therapy: how a catalytic RNA can be used to inhibit gene function.
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21 January 2018
Intracellular expression and function of antisense catalytic RNAs
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retrieved
21 January 2018
Ribozyme and free alkylated base: a dual approach for sensitizing Mex+ cells to the alkylating antineoplastic drug
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21 January 2018
Dopamine D(2) receptor ribozyme inhibits quinpirole-induced stereotypy in rats
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21 January 2018
Bioactivity of anti-angiogenic ribozymes targeting Flt-1 and KDR mRNA.
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21 January 2018
Progress in antisense technology: the end of the beginning
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21 January 2018
Antisense therapeutics: is it as simple as complementary base recognition?
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21 January 2018
Specific hammerhead ribozyme-mediated cleavage of mutant N-ras mRNA in vitro and ex vivo. Oligoribonucleotides as therapeutic agents
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21 January 2018
Inhibition of luciferase expression by synthetic hammerhead ribozymes and their cellular uptake
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21 January 2018
Transient transfection of a synthetic hammerhead ribozyme targeted against human MGMT gene to cells in culture potentiates the genotoxicity of the alkylation damage induced by mitozolomide
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21 January 2018
Inhibition of hepatitis C virus (HCV)-RNA-dependent translation and replication of a chimeric HCV poliovirus using synthetic stabilized ribozymes
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21 January 2018
The kinetic mechanism of the hairpin ribozyme in vivo: influence of RNA helix stability on intracellular cleavage kinetics
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21 January 2018
Identification and partial purification of human double strand RNase activity. A novel terminating mechanism for oligoribonucleotide antisense drugs
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21 January 2018
mRNA localization signals can enhance the intracellular effectiveness of hammerhead ribozymes
1 reference
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retrieved
21 January 2018
A small nucleolar RNA:ribozyme hybrid cleaves a nucleolar RNA target in vivo with near-perfect efficiency
1 reference
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Crossref
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retrieved
21 January 2018
Ribozyme-mediated inhibition of HIV 1 suggests nucleolar trafficking of HIV-1 RNA.
1 reference
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retrieved
21 January 2018
Identifiers
DOI
10.1002/1097-0282(1999)52:3<147::AID-BIP40>3.0.CO;2-I
0 references
PubMed ID
11169382
1 reference
stated in
Europe PubMed Central
PubMed ID
11169382
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11169382%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
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