(Q73435439)

English

Escherichia coli cytosine deaminase: the kinetics and thermodynamics for binding of cytosine to the apoenzyme and the Zn(2+) holoenzyme are similar

scientific article published on 01 February 2000

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10669789%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Escherichia coli cytosine deaminase: the kinetics and thermodynamics for binding of cytosine to the apoenzyme and the Zn(2+) holoenzyme are similar (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10669789%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Escherichia coli

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inferred from title

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author name string

D J Porter

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10669789%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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publication date

1 February 2000

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Europe PubMed Central

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3 November 2019

Biochimica et Biophysica Acta

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10669789%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1476

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10669789%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10669789%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

239-252

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10669789%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system

1 reference

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Phase I study of direct administration of a replication deficient adenovirus vector containing the E. coli cytosine deaminase gene to metastatic colon carcinoma of the liver in association with the oral administration of the pro-drug 5-fluorocytosine

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Site-directed mutagenesis of active site glutamate-217 in mouse adenosine deaminase

1 reference

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Mutations affecting transition-state stabilization by residues coordinating zinc at the active site of cytidine deaminase.

1 reference

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A kinetic analysis of the oligonucleotide-modulated ATPase activity of the helicase domain of the NS3 protein from hepatitis C virus. The first cycle of interaction of ATP with the enzyme is unique

1 reference

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Atomic structure of adenosine deaminase complexed with a transition-state analog: understanding catalysis and immunodeficiency mutations

1 reference

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A pre-transition-state mimic of an enzyme: X-ray structure of adenosine deaminase with bound 1-deazaadenosine and zinc-activated water

1 reference

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The rate of formation of transition-state analogs in the active site of adenosine deaminase is encounter-controlled: implications for the mechanism

1 reference

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Cloning and nucleotide sequence of the Escherichia coli cytidine deaminase (ccd) gene

1 reference

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inferred from DOI database lookup

Cytidine deaminase. The 2.3 A crystal structure of an enzyme: transition-state analog complex

1 reference

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7 January 2021

based on heuristic

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Cytidine deaminase complexed to 3-deazacytidine: a "valence buffer" in zinc enzyme catalysis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of AMP deaminase by zinc ions

1 reference

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7 January 2021

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An evolutionary treasure: unification of a broad set of amidohydrolases related to urease

1 reference

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7 January 2021

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inferred from DOI database lookup

AtzC is a new member of the amidohydrolase protein superfamily and is homologous to other atrazine-metabolizing enzymes.

1 reference

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7 January 2021

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inferred from DOI database lookup

Role of glutamate-104 in generating a transition state analogue inhibitor at the active site of cytidine deaminase

1 reference

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7 January 2021

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Transition-state stabilization by adenosine deaminase: 1,6-addition of water to purine ribonucleoside, the enzyme's affinity for 6-hydroxy-1,6-dihydropurine ribonucleoside, and the effective concentration of substrate water at the active site

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Crystallographic observation of a trapped tetrahedral intermediate in a metalloenzyme

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7 January 2021

based on heuristic

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Enzyme-substrate complexes of adenosine and cytidine deaminases: absence of accumulation of water adducts

1 reference

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based on heuristic

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The protonated form of 1-N6-etheno-[erythro-9-(2-hydroxy-3-nonyl)] adenine is identified at the active site of adenosine deaminase

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0167-4838(99)00246-0

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10669789%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10669789%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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