(Q73466818)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12781336%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

title

Human MDR1 polymorphism: G2677T/A and C3435T have no effect on MDR1 transport activities (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12781336%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

author name string

Naomi Morita

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12781336%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Toshio Yasumori

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12781336%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Kazuo Nakayama

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12781336%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

language of work or name

English

0 references

publication date

1 June 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12781336%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

published in

Biochemical Pharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12781336%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

volume

65

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12781336%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12781336%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

page(s)

1843-1852

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12781336%20AND%20SRC:MED&resulttype=core&format=json

Pharmacogenomics: the inherited basis for interindividual differences in drug response

4 November 2019

cites work

1 reference

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Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data.

7 January 2021

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Role of transport proteins in drug absorption, distribution and excretion

7 January 2021

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Mutations in the canilicular multispecific organic anion transporter (cMOAT) gene, a novel ABC transporter, in patients with hyperbilirubinemia II/Dubin-Johnson syndrome

7 January 2021

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ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells

7 January 2021

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Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

7 January 2021

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Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

7 January 2021

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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

7 January 2021

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Pharmacokinetic role of P-glycoprotein in oral bioavailability and intestinal secretion of grepafloxacin in vivo

7 January 2021

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Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine

7 January 2021

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Pharmacokinetic and prognostic significance of intestinal MDR1 expression in recipients of living-donor liver transplantation

7 January 2021

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Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

7 January 2021

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Identification of functionally variant MDR1 alleles among European Americans and African Americans

7 January 2021

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MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects

7 January 2021

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MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity

7 January 2021

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Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.

7 January 2021

1 reference

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P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance.

7 January 2021

1 reference

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Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system.

7 January 2021

1 reference

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Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein.

7 January 2021

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Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations

7 January 2021

1 reference

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Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients

7 January 2021

1 reference

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Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene

7 January 2021

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Recombinase-mediated gene activation and site-specific integration in mammalian cells

7 January 2021

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Site-specific integration of targeted DNA into animal cell genomes

7 January 2021

1 reference

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Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects.

7 January 2021

1 reference

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MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine

7 January 2021

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Relationship between expression level of P-glycoprotein and daunorubicin transport in LLC-PK1 cells transfected with human MDR1 gene

7 January 2021

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Endogenous drug transporters in in vitro and in vivo models for the prediction of drug disposition in man.

7 January 2021

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Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

7 January 2021

1 reference

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A basolateral sorting signal is encoded in the alpha-subunit of Na-K-ATPase

7 January 2021

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Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans

7 January 2021

1 reference

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Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function

7 January 2021

1 reference

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Impaired protein maturation of the conjugate export pump multidrug resistance protein 2 as a consequence of a deletion mutation in Dubin-Johnson syndrome

7 January 2021

1 reference

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Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

7 January 2021

1 reference

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Saint John's wort: an in vitro analysis of P-glycoprotein induction due to extended exposure

7 January 2021

1 reference

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10.1016/S0006-2952(03)00178-3

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12781336%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference