(Q73574729)

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Brain uptake and receptor binding of two [11C]labelled selective high affinity NK1-antagonists, GR203040 and GR205171--PET studies in rhesus monkey

scientific article published on 01 February 2000

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5 November 2019

Brain uptake and receptor binding of two [11C]labelled selective high affinity NK1-antagonists, GR203040 and GR205171--PET studies in rhesus monkey (English)

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5 November 2019

Bengt Långström

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B Långström

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5 November 2019

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M Bergström

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5 November 2019

K J Fasth

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5 November 2019

G Kilpatrick

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5 November 2019

P Ward

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5 November 2019

K M Cable

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5 November 2019

M D Wipperman

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5 November 2019

D R Sutherland

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5 November 2019

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1 February 2000

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5 November 2019

Neuropharmacology

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5 November 2019

39

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5 November 2019

4

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5 November 2019

664-670

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5 November 2019

The pharmacology of GR203040, a novel, potent and selective non-peptide tachykinin NK1 receptor antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900182-3

7 January 2021

Measurement of human cerebral monoamine oxidase type B (MAO-B) activity with positron emission tomography (PET): a dose ranging study with the reversible inhibitor Ro 19-6327

1 reference

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7 January 2021

MAO-A inhibition in brain after dosing with esuprone, moclobemide and placebo in healthy volunteers: in vivo studies with positron emission tomography

1 reference

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7 January 2021

Synthesis of a nonpeptide carbon-11 labeled substance P antagonist for PET studies

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900182-3

7 January 2021

Phylogeny of tachykinin receptor localization in the vertebrate central nervous system: apparent absence of neurokinin-2 and neurokinin-3 binding sites in the human brain

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900182-3

7 January 2021

Monoamine oxidase B (MAO B) inhibitor therapy in Parkinson's disease: the degree and reversibility of human brain MAO B inhibition by Ro 19 6327.

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900182-3

7 January 2021

The broad-spectrum anti-emetic activity of the novel non-peptide tachykinin NK1 receptor antagonist GR203040

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900182-3

7 January 2021

GR205171: a novel antagonist with high affinity for the tachykinin NK1 receptor, and potent broad-spectrum anti-emetic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900182-3

7 January 2021

Performance characteristics of an eight-ring whole body PET scanner

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900182-3

7 January 2021

Distinct mechanism for antidepressant activity by blockade of central substance P receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900182-3

7 January 2021

Synthesis of a 11C-labeled NK1 receptor ligand for PET studies

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900182-3

7 January 2021

Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900182-3

7 January 2021

Discovery of an orally bioavailable NK1 receptor antagonist, (2S,3S)-(2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine (GR203040), with potent antiemetic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0028-3908%2899%2900182-3

7 January 2021

Identifiers

10.1016/S0028-3908(99)00182-3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10728887%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10728887%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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