(Q73626538)

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Molecular and structural basis of the specificity of a neutralizing acetylcholine receptor-mimicking antibody, using combined mutational and molecular modeling analyses

scientific article published on 01 July 2000

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scholarly article

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5 November 2019

Molecular and structural basis of the specificity of a neutralizing acetylcholine receptor-mimicking antibody, using combined mutational and molecular modeling analyses (English)

1 reference

Europe PubMed Central

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5 November 2019

Karine Merienne

2

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5 November 2019

author name string

Germain N

1

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5 November 2019

Zinn-Justin S

3

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5 November 2019

Boulain JC

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5 November 2019

Ducancel F

5

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5 November 2019

Ménez A

6

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1 July 2000

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5 November 2019

Journal of Biological Chemistry

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5 November 2019

275

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5 November 2019

21578-21586

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5 November 2019

28

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5 November 2019

A monoclonal antibody which recognized the functional site of snake neurotoxins and which neutralizes all short-chain variants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Mimicry between receptors and antibodies. Identification of snake toxin determinants recognized by the acetylcholine receptor and an acetylcholine receptor-mimicking monoclonal antibody

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Three-Dimensional Structure of Immunoglobulins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Antibody-antigen complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Structural model of the anti-snake-toxin antibody, M alpha 2,3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

The functional architecture of an acetylcholine receptor-mimicking antibody.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Three-dimensional solution structure of a curaremimetic toxin from Naja nigricollis venom: a proton NMR and molecular modeling study

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Structural modeling of the complex between an acetylcholine receptor-mimicking antibody and its snake toxin antigen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus)

1 reference

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21 January 2018

Estimating the contribution of engineered surface electrostatic interactions to protein stability by using double-mutant cycles

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Energetics of protein-protein interactions: analysis of the barnase-barstar interface by single mutations and double mutant cycles.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Revealing the architecture of a K+ channel pore through mutant cycles with a peptide inhibitor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Spatial localization of the K+ channel selectivity filter by mutant cycle-based structure analysis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

High-level production and isotope labeling of snake neurotoxins, disulfide-rich proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Neutralizing monoclonal antibody specific for Naja nigricollis toxin .alpha.: preparation, characterization and localization of the antigenic binding site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Protein-protein recognition analyzed by docking simulation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Computer analysis of protein-protein interaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Protein-protein interfaces: architectures and interactions in protein-protein interfaces and in protein cores. Their similarities and differences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Critical interactions in binding antibody NC41 to influenza N9 neuraminidase: amino acid contacts on the antibody heavy chain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Mapping of two "neutralizing" epitopes of a snake curaremimetic toxin by proton nuclear magnetic resonance spectroscopy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

On the attribution of binding energy in antigen-antibody complexes McPC 603, D1.3, and HyHEL-5.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Structure of an antibody-lysozyme complex unexpected effect of conservative mutation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Analysis of binding interactions in an idiotope-antiidiotope protein-protein complex by double mutant cycles

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Identification of pairwise interactions in the alpha-neurotoxin-nicotinic acetylcholine receptor complex through double mutant cycles

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

A mutational analysis of binding interactions in an antigen-antibody protein-protein complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Analysis of protein–protein interactions by mutagenesis: direct versus indirect effects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Effects of substitutions in the binding surface of an antibody on antigen affinity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

The atomic structure of protein-protein recognition sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Interactions of protein antigens with antibodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Comparison of a structural and a functional epitope

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Meeting review: the Second meeting on the Critical Assessment of Techniques for Protein Structure Prediction (CASP2), Asilomar, California, December 13-16, 1996.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

A mechanism for ion selectivity in potassium channels: computational studies of cation-pi interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp

1 reference

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21 January 2018

From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor

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21 January 2018

Monoclonal anti-idiotypic antibody mimics the CD4 receptor and binds human immunodeficiency virus

1 reference

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21 January 2018

Rational design of receptor-specific variants of human growth hormone

1 reference

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21 January 2018

Antibody and HIV-1 gp120 recognition of CD4 undermines the concept of mimicry between antibodies and receptors

1 reference

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21 January 2018

Improved secondary structure predictions for a nicotinic receptor subunit: incorporation of solvent accessibility and experimental data into a two-dimensional representation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Nonidentity of the alpha-neurotoxin binding sites on the nicotinic acetylcholine receptor revealed by modification in alpha-neurotoxin and receptor structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001794200

21 January 2018

Subunit interface selectivity of the alpha-neurotoxins for the nicotinic acetylcholine receptor

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M001794200

1 reference

Europe PubMed Central

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5 November 2019

1 reference

Europe PubMed Central

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5 November 2019

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