(Q73689621)

English

Pharmacokinetic-pharmacodynamic correlation of lamotrigine, flunarizine, loreclezole, CGP40116 and CGP39551 in the cortical stimulation model

scientific article published on 01 June 2000

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10771257%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Pharmacokinetic-pharmacodynamic correlation of lamotrigine, flunarizine, loreclezole, CGP40116 and CGP39551 in the cortical stimulation model (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10771257%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

pharmacodynamics

1 reference

based on heuristic

inferred from title

Meindert Danhof

5

object named as

M Danhof

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10771257%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

author name string

O E Della Paschoa

1

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10771257%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

A Hoogerkamp

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10771257%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

P M Edelbroek

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10771257%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

R A Voskuyl

4

1 reference

Europe PubMed Central

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6 November 2019

publication date

1 June 2000

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10771257%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Epilepsy Research

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10771257%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

40

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Europe PubMed Central

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6 November 2019

1

1 reference

Europe PubMed Central

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6 November 2019

41-52

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10771257%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

In vivo studies on the mechanism of action of the broad spectrum anticonvulsant loreclezole

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

In vitro studies on the broad spectrum anticonvulsant loreclezole in the hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

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inferred from DOI database lookup

New antiepileptic drugs

1 reference

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7 January 2021

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Comparative pharmacokinetics of the newer antiepileptic drugs

1 reference

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7 January 2021

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Relevance of the application of pharmacokinetic-pharmacodynamic modelling concepts in drug development. The "wooden shoe' paradigm

1 reference

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7 January 2021

based on heuristic

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Anticonvulsant Activity of Two Orally Active Competitive N-Methyl-D-Aspartate Antagonists, CGP 37849 and CGP 39551, Against Sound-Induced Seizures in DBA/2 Mice and Photically Induced Myoclonus in Papio papio

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

An in vitro investigation of the action of lamotrigine on neuronal voltage-activated sodium channels

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Weak anticonvulsant activity of CGP 37849 and CGP 39551 against kindled seizures following systemic administration

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Competitive NMDA receptor antagonists raise electrically kindled generalized seizure thresholds

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The anticonvulsant effect of the broad spectrum anticonvulsant loreclezole may be mediated in part by serotonin in rats: a microdialysis study

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacokinetic-pharmacodynamic modelling in pre-clinical investigations: principles and perspectives

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Lack of effect of flumazenil and CGS 8216 on the anxiolytic-like properties of loreclezole

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparative efficiencies of randomized concentration- and dose-controlled clinical trials.

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

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Functional properties of recombinant GABA(A) receptors composed of single or multiple beta subunit subtypes

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

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Anticonvulsant pharmacodynamics and disposition of triazolam in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Rising dose study of safety and tolerance of flunarizine

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The diversity of GABAA receptors. Pharmacological and electrophysiological properties of GABAA channel subtypes

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Flunarizine A Review of Its Pharmacodynamic and Pharmacokinetic Properties and Therapeutic Use

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Flunarizine of limited value in children with intractable epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Actions of Ca2+ antagonists on two types of Ca2+ channels in rat aorta smooth muscle cells in primary culture.

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The new generation of antiepileptic drugs: advantages and disadvantages

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Design of an individualized fixed-dose clinical trial to test the antiepileptic efficacy of a plasma flunarizine concentration

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Dose-related and treatment-dependent quantitative EEG effects of antiepileptic compounds in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Double-blind, placebo controlled, crossover study of lamotrigine in treatment resistant partial seizures

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The competitive NMDA receptor antagonists CGP 37849 and CGP 39551 are potent, orally-active anticonvulsants in rodents

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Increasing plasma concentration tolerability study of flunarizine in comedicated epileptic patients

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Determination of the threshold for convulsions by direct cortical stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Properties of the convulsive threshold determined by direct cortical stimulation in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Anticonvulsant effect of polyunsaturated fatty acids in rats, using the cortical stimulation model

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The modulatory action of loreclezole at the gamma-aminobutyric acid type A receptor is determined by a single amino acid in the beta 2 and beta 3 subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of the glycine/NMDA receptor partial agonist, D-cycloserine, on seizure threshold and some pharmacodynamic effects of MK-801 in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of various antiepileptic drugs on plasma levels of lamotrigine, a novel antiepileptic, in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2800%2900102-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0920-1211(00)00102-9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10771257%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10771257%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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