(Q73694633)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773822%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Regions essential for the interaction between Bcl-2 and SMN, the spinal muscular atrophy disease gene product (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773822%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

main subject

spinal muscular atrophy

1 reference

1 reference

Sato K

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773822%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Eguchi Y

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773822%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Kodama TS

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773822%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Tsujimoto Y

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773822%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

publication date

1 April 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773822%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

6 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773822%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773822%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773822%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

page(s)

374-383

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773822%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4400660

6 November 2019

exact match

0 references

cites work

Classification of spinal muscular atrophies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Identification and characterization of a spinal muscular atrophy-determining gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

A multicopy transcription-repair gene, BTF2p44, maps to the SMA region and demonstrates SMA associated deletions.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Identification of a candidate modifying gene for spinal muscular atrophy by comparative genomics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

The role of the SMN gene in proximal spinal muscular atrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Molecular analysis of candidate genes on chromosome 5q13 in autosomal recessive spinal muscular atrophy: evidence of homozygous deletions of the SMN gene in unaffected individuals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Deletions in the survival motor neuron gene on 5q13 in autosomal recessive spinal muscular atrophy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

A frame–shift deletion in the survival motor neuron gene in Spanish spinal muscular atrophy patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Molecular analysis of the SMN and NAIP genes in Spanish spinal muscular atrophy (SMA) families and correlation between number of copies of cBCD541 and SMA phenotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Gene deletions in spinal muscular atrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Frameshift mutation in the survival motor neuron gene in a severe case of SMA type I

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

An 11 base pair duplication in exon 6 of the SMN gene produces a type I spinal muscular atrophy (SMA) phenotype: further evidence for SMN as the primary SMA-determining gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Missense mutation clustering in the survival motor neuron gene: a role for a conserved tyrosine and glycine rich region of the protein in RNA metabolism?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Missense mutations in exon 6 of the survival motor neuron gene in patients with spinal muscular atrophy (SMA).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

SMN(T) and NAIP mutations in Canadian families with spinal muscular atrophy (SMA): genotype/phenotype correlations with disease severity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Spinal muscular atrophy--clinical and genetic correlations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Diagnosis of spinal muscular atrophy in an SMN non-deletion patient using a quantitative PCR screen and mutation analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Correlation between severity and SMN protein level in spinal muscular atrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Differential SMN2 expression associated with SMA severity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Genomic variation and gene conversion in spinal muscular atrophy: implications for disease process and clinical phenotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Correlation of SMNt and SMNc gene copy number with age of onset and survival in spinal muscular atrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Gene conversion at the SMN locus in autosomal recessive spinal muscular atrophy does not predict a mild phenotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Identification of proximal spinal muscular atrophy carriers and patients by analysis of SMNT and SMNC gene copy number

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

A novel nuclear structure containing the survival of motor neurons protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

A novel function for SMN, the spinal muscular atrophy disease gene product, in pre-mRNA splicing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

The domain encoded by exon 2 of the survival motor neuron protein mediates nucleic acid binding.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

The RNA-binding properties of SMN: deletion analysis of the zebrafish orthologue defines domains conserved in evolution

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Identification of survival motor neuron as a transcriptional activator-binding protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Role of Bcl-2 family proteins in apoptosis: apoptosomes or mitochondria?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Bcl-2 targets the protein kinase Raf-1 to mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Bcl-2 phosphorylation required for anti-apoptosis function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Cytochrome c: can't live with it--can't live without it.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Interaction between the C. elegans cell-death regulators CED-9 and CED-4.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Interaction and regulation of subcellular localization of CED-4 by CED-9

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Developmental patterns of BCL-2 and BCL-X polypeptide expression in the human spinal cord.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Crystal structure of rat Bcl-xL. Implications for the function of the Bcl-2 protein family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

The protein bcl-2 alpha does not require membrane attachment, but two conserved domains to suppress apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Structure-function analysis of Bcl-2 protein. Identification of conserved domains important for homodimerization with Bcl-2 and heterodimerization with Bax.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

A peptide sequence from Bax that converts Bcl-2 into an activator of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Evidence for alpha-helical conformation of an essential N-terminal region in the human Bcl2 protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Analysis of mutations in the tudor domain of the survival motor neuron protein SMN

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

SMN oligomerization defect correlates with spinal muscular atrophy severity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Intragenic telSMN mutations: frequency, distribution, evidence of a founder effect, and modification of the spinal muscular atrophy phenotype by cenSMN copy number.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Quantitative analysis of survival motor neuron copies: identification of subtle SMN1 mutations in patients with spinal muscular atrophy, genotype-phenotype correlation, and implications for genetic counseling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Epitope tagging and protein surveillance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Efficient selection for high-expression transfectants with a novel eukaryotic vector

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400660

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4400660

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10773822%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference